{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:58Z","timestamp":1791928918864,"version":"4.3.4"},"reference-count":74,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"10","license":[{"start":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T00:00:00Z","timestamp":1787097600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2026,8,19]]},"DOI":"10.1167\/iovs.67.10.47","type":"journal-article","created":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T13:30:36Z","timestamp":1787146236000},"page":"47","source":"Crossref","is-referenced-by-count":2,"title":["In Vivo Human Cone Photoreceptor Inner Segment Diameter Database Using Adaptive Optics Retinal Imaging"],"prefix":"10.1167","volume":"67","author":[{"given":"Nancy","family":"Aguilera","sequence":"first","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siddhanth","family":"Iyer","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria J.","family":"Cruz","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Li","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Megan","family":"Wall","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC, Rockville, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marisa","family":"Kallem","sequence":"additional","affiliation":[{"name":"The Emmes Company, LLC, Rockville, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrei","family":"Volkov","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian P.","family":"Brooks","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wadih M.","family":"Zein","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laryssa A.","family":"Huryn","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Liu","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnny","family":"Tam","sequence":"additional","affiliation":[{"name":"National Eye Institute, National Institutes of Health, Bethesda, Maryland, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"2884","DOI":"10.1364\/JOSAA.14.002884","article-title":"Supernormal vision and high-resolution retinal imaging through adaptive optics","volume":"14","author":"Liang","year":"1997","journal-title":"J Opt Soc Am A Opt Image Sci Vis"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"387","DOI":"10.1364\/BOE.472274","article-title":"Twenty-five years of clinical applications using adaptive optics ophthalmoscopy","volume":"14","author":"Morgan","year":"2022","journal-title":"Biomed Opt Express"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"405","DOI":"10.1364\/OE.10.000405","article-title":"Adaptive optics scanning laser ophthalmoscopy","volume":"10","author":"Roorda","year":"2002","journal-title":"Opt Express"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"1275308","DOI":"10.3389\/fmed.2023.1275308","article-title":"Sex-related difference in the retinal structure of young adults: a machine learning approach","volume":"10","author":"Farias","year":"2023","journal-title":"Front Med"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"213","DOI":"10.3109\/02713683.2014.952828","article-title":"Effects of sex and age on the normal retinal and choroidal structures on optical coherence tomography","volume":"40","author":"Ooto","year":"2015","journal-title":"Curr Eye Res"},{"issue":"6","key":"bib6","doi-asserted-by":"publisher","first-page":"BIO255","DOI":"10.1167\/iovs.17-21868","article-title":"Photoreceptor-based biomarkers in AOSLO retinal imaging","volume":"58","author":"Litts","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib7","doi-asserted-by":"publisher","first-page":"e0151380","DOI":"10.1371\/journal.pone.0151380","article-title":"Investigation of adaptive optics imaging biomarkers for detecting pathological changes of the cone mosaic in patients with type 1 diabetes mellitus","volume":"11","author":"Lombardo","year":"2016","journal-title":"PLoS One"},{"issue":"5","key":"bib8","first-page":"E692","article-title":"Subclinical capillary changes in non-proliferative diabetic retinopathy","volume":"89","author":"Tam","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib9","doi-asserted-by":"publisher","first-page":"6","DOI":"10.1167\/tvst.9.2.6","article-title":"Insights into systemic disease through retinal imaging-based oculomics","volume":"9","author":"Wagner","year":"2020","journal-title":"Trans Vis Sci Tech"},{"issue":"6","key":"bib10","doi-asserted-by":"publisher","first-page":"e124904","DOI":"10.1172\/jci.insight.124904","article-title":"Longitudinal adaptive optics fluorescence microscopy reveals cellular mosaicism in patients","volume":"4","author":"Jung","year":"2019","journal-title":"JCI insight"},{"issue":"1","key":"bib11","doi-asserted-by":"publisher","first-page":"105755","DOI":"10.1016\/j.isci.2022.105755","article-title":"Visualization of erythrocyte stasis in the living human eye in health and disease","volume":"26","author":"Li","year":"2023","journal-title":"Iscience"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"9257","DOI":"10.1167\/iovs.11-8481","article-title":"Disruption of the retinal parafoveal capillary network in type 2 diabetes before the onset of diabetic retinopathy","volume":"52","author":"Tam","year":"2011","journal-title":"Invest ophthalmol Vis Sci"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"5543","DOI":"10.1364\/BOE.9.005543","article-title":"Light propagation and capture in cone photoreceptors","volume":"9","author":"Meadway","year":"2018","journal-title":"Biomed Opt Express"},{"issue":"5","key":"bib14","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1167\/2.5.4","article-title":"Optical fiber properties of individual human cones","volume":"2","author":"Roorda","year":"2002","journal-title":"J Vis"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"4244","DOI":"10.1167\/iovs.14-14542","article-title":"In vivo imaging of human cone photoreceptor inner segments","volume":"55","author":"Scoles","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"4431","DOI":"10.1167\/iovs.15-16547","article-title":"Normal perceptual sensitivity arising from weakly reflective cone photoreceptors","volume":"56","author":"Bruce","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib17","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1007\/978-3-030-27378-1_22","article-title":"Dysflective cones","author":"Duncan","year":"2019","journal-title":"Retinal Degenerative Diseases: Mechanisms and Experimental Therapy"},{"issue":"3","key":"bib18","doi-asserted-by":"publisher","first-page":"40","DOI":"10.1167\/iovs.61.3.40","article-title":"Photoreceptor structure in GNAT2-associated achromatopsia","volume":"61","author":"Georgiou","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"629214","DOI":"10.3389\/fnagi.2021.629214","article-title":"Persistent dark cones in oligocone trichromacy revealed by multimodal adaptive optics ophthalmoscopy","volume":"13","author":"Li","year":"2021","journal-title":"Front Aging Neurosci"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"3081","DOI":"10.1364\/BOE.8.003081","article-title":"Unsupervised identification of cone photoreceptors in non-confocal adaptive optics scanning light ophthalmoscope images","volume":"8","author":"Bergeles","year":"2017","journal-title":"Biomed Opt Express"},{"issue":"5","key":"bib21","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1167\/tvst.8.5.26","article-title":"Fully automated estimation of spacing and density for retinal mosaics","volume":"8","author":"Cooper","year":"2019","journal-title":"Trans Vis Sci Tech"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"2036","DOI":"10.1364\/BOE.7.002036","article-title":"Automatic detection of cone photoreceptors in split detector adaptive optics scanning light ophthalmoscope images","volume":"7","author":"Cunefare","year":"2016","journal-title":"Biomed Opt Express"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"3815","DOI":"10.1364\/BOE.10.003815","article-title":"RAC-CNN: multimodal deep learning based automatic detection and classification of rod and cone photoreceptors in adaptive optics scanning light ophthalmoscope images","volume":"10","author":"Cunefare","year":"2019","journal-title":"Biomed Opt Express"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"4477","DOI":"10.1167\/iovs.16-21003","article-title":"Automated photoreceptor cell identification on nonconfocal adaptive optics images using multiscale circular voting","volume":"58","author":"Liu","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"4639","DOI":"10.1167\/iovs.18-24734","article-title":"Cone photoreceptor cell segmentation and diameter measurement on adaptive optics images using circularly constrained active contour model","volume":"59","author":"Liu","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"2820","DOI":"10.1109\/TMI.2021.3055483","article-title":"Active cell appearance model induced generative adversarial networks for annotation-efficient cell segmentation and identification on adaptive optics retinal images","volume":"40","author":"Liu","year":"2021","journal-title":"IEEE Trans Med Imaging"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"2428","DOI":"10.1167\/iovs.15-18246","article-title":"Assessing photoreceptor structure in retinitis pigmentosa and Usher syndrome","volume":"57","author":"Sun","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"45","DOI":"10.3928\/23258160-20161219-06","article-title":"Comparing parafoveal cone photoreceptor mosaic metrics in younger and older age groups using an adaptive optics retinal camera","volume":"48","author":"Jacob","year":"2017","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"key":"bib33","first-page":"3278","article-title":"Aging of the human photoreceptor mosaic: evidence for selective vulnerability of rods in central retina","volume":"34","author":"Curcio","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.exer.2012.12.011","article-title":"A study of factors affecting the human cone photoreceptor density measured by adaptive optics scanning laser ophthalmoscope","volume":"108","author":"Park","year":"2013","journal-title":"Exp Eye Res"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"7376","DOI":"10.1167\/iovs.11-7199","article-title":"Variation of cone photoreceptor packing density with retinal eccentricity and age","volume":"52","author":"Song","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib36","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.ajo.2009.09.025","article-title":"Retinal thickness analysis by race, gender, and age using Stratus OCT","volume":"149","author":"Kashani","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"357","DOI":"10.1016\/j.ophtha.2019.09.019","article-title":"Sex-specific differences in circumpapillary retinal nerve fiber layer thickness","volume":"127","author":"Li","year":"2020","journal-title":"Ophthalmology"},{"issue":"1","key":"bib38","doi-asserted-by":"publisher","first-page":"17013","DOI":"10.1038\/s41598-024-67671-w","article-title":"Sex differences in choroidal vessels using novel wide-field choroidal en-face images from optical coherence tomography","volume":"14","author":"Mihara","year":"2024","journal-title":"Sci Rep"},{"issue":"3","key":"bib39","doi-asserted-by":"publisher","first-page":"e0194169","DOI":"10.1371\/journal.pone.0194169","article-title":"Impacts of age and sex on retinal layer thicknesses measured by spectral domain optical coherence tomography with Spectralis","volume":"13","author":"Nieves-Moreno","year":"2018","journal-title":"PLoS One"},{"issue":"12","key":"bib40","doi-asserted-by":"publisher","first-page":"e0278925","DOI":"10.1371\/journal.pone.0278925","article-title":"Spatial characterization of the effect of age and sex on macular layer thicknesses and foveal pit morphology","volume":"17","author":"Romero-Bascones","year":"2022","journal-title":"PLoS One"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"262","DOI":"10.1111\/aos.13337","article-title":"Macular thickness in healthy eyes of adults (N= 4508) and relation to sex, age and refraction: the Troms\u00f8 Eye Study (2007\u20132008)","volume":"95","author":"von Hanno","year":"2017","journal-title":"Acta ophthalmol"},{"issue":"46","key":"bib42","doi-asserted-by":"publisher","first-page":"e5441","DOI":"10.1097\/MD.0000000000005441","article-title":"Effect of age and sex on retinal layer thickness and volume in normal eyes","volume":"95","author":"Won","year":"2016","journal-title":"Medicine"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"1757","DOI":"10.1364\/BOE.2.001757","article-title":"Reflective afocal broadband adaptive optics scanning ophthalmoscope","volume":"2","author":"Dubra","year":"2011","journal-title":"Biomed Opt Express"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1364\/OPTICA.414206","article-title":"In-vivo sub-diffraction adaptive optics imaging of photoreceptors in the human eye with annular pupil illumination and sub-Airy detection","volume":"8","author":"Lu","year":"2021","journal-title":"Optica"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"2527","DOI":"10.1364\/BOE.4.002527","article-title":"In vivo imaging of retinal pigment epithelium cells in age related macular degeneration","volume":"4","author":"Rossi","year":"2013","journal-title":"Biomed Opt Express"},{"issue":"2","key":"bib48","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1111\/j.1475-1313.1989.tb00851.x","article-title":"Proposals for new reduced and schematic eyes","volume":"9","author":"Bennett","year":"1989","journal-title":"Ophthalmic Physiol Opt"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"2992","DOI":"10.1167\/iovs.16-19072","article-title":"Evaluating descriptive metrics of the human cone mosaic","volume":"57","author":"Cooper","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1002\/cne.902920402","article-title":"Human photoreceptor topography","volume":"292","author":"Curcio","year":"1990","journal-title":"J Comp Neurol"},{"issue":"10","key":"bib51","doi-asserted-by":"publisher","first-page":"36","DOI":"10.1167\/iovs.64.10.36","article-title":"Cone photoreceptor morphology in choroideremia assessed using non-confocal split-detection adaptive optics scanning light ophthalmoscopy","volume":"64","author":"Xu","year":"2023","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"4934","DOI":"10.1167\/iovs.13-11913","article-title":"Effect of age on individual retinal layer thickness in normal eyes as measured with spectral-domain optical coherence tomography","volume":"54","author":"Demirkaya","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"2668","DOI":"10.1167\/iovs.07-1000","article-title":"Macular thickness assessment in healthy eyes based on ethnicity using Stratus OCT optical coherence tomography","volume":"49","author":"Kelty","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"3913","DOI":"10.1167\/iovs.09-4189","article-title":"Macular thickness variations with sex, age, and axial length in healthy subjects: a spectral domain\u2013optical coherence tomography study","volume":"51","author":"Song","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1167\/iovs.10-5886","article-title":"Race-and sex-related differences in retinal thickness and foveal pit morphology","volume":"52","author":"Wagner-Schuman","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib56","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1038\/sj.eye.6701466","article-title":"Relationship of gender, body mass index, and axial length with central retinal thickness using optical coherence tomography","volume":"19","author":"Wong","year":"2005","journal-title":"Eye"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"244","DOI":"10.3758\/BF03196159","article-title":"Richer color experience in observers with multiple photopigment opsin genes","volume":"8","author":"Jameson","year":"2001","journal-title":"Psychon Bull Rev"},{"key":"bib58","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1016\/0042-6989(93)90143-K","article-title":"A study of women heterozygous for colour deficiencies","volume":"33","author":"Jordan","year":"1993","journal-title":"Vision Res"},{"issue":"1","key":"bib59","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1186\/2042-6410-3-20","article-title":"Sex & vision I: Spatio-temporal resolution","volume":"3","author":"Abramov","year":"2012","journal-title":"Biol Sex Differ"},{"issue":"2","key":"bib60","doi-asserted-by":"publisher","first-page":"31","DOI":"10.3390\/biology8020031","article-title":"Mitochondrial dysfunction in the aging retina","volume":"8","author":"Eells","year":"2019","journal-title":"Biology"},{"key":"bib61","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1017\/S0952523802194028","article-title":"Photoreceptor inner segments in monkey and human retina: mitochondrial density, optics, and regional variation","volume":"19","author":"Hoang","year":"2002","journal-title":"Vis Neurosci"},{"issue":"1","key":"bib62","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1167\/iovs.61.1.1","article-title":"Aging of the human retina. Differential loss of neurons and retinal pigment epithelial cells","volume":"33","author":"Gao","year":"1992","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib63","doi-asserted-by":"publisher","first-page":"732287","DOI":"10.3389\/fnagi.2021.732287","article-title":"The relationship between perifoveal L-cone isolating visual acuity and cone photoreceptor spacing\u2014understanding the transition between healthy aging and early AMD","volume":"13","author":"Baraas","year":"2021","journal-title":"Front Aging Neurosci"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1111\/opo.12670","article-title":"Cones in ageing and harsh environments: the neural economy hypothesis","volume":"40","author":"Elsner","year":"2020","journal-title":"Ophthalmic Physiol Opt"},{"key":"bib65","first-page":"415","article-title":"Contrast sensitivity decline with ageing: a neural or optical phenomenon?","volume":"7","author":"Elliott","year":"1987","journal-title":"Ophthalmic Physiol Opt"},{"issue":"7","key":"bib66","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/08164622.2025.2483265","article-title":"Age-related changes in contrast sensitivity function under different illumination conditions","volume":"108","author":"Herrero-Gracia","year":"2025","journal-title":"Clin Exp Optom"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"3975","DOI":"10.1016\/S0042-6989(99)00092-9","article-title":"Aging and dark adaptation","volume":"39","author":"Jackson","year":"1999","journal-title":"Vision Res"},{"key":"bib68","doi-asserted-by":"publisher","first-page":"3283","DOI":"10.1167\/iovs.06-1422","article-title":"High-resolution imaging with adaptive optics in patients with inherited retinal degeneration","volume":"48","author":"Duncan","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib69","doi-asserted-by":"publisher","first-page":"3984","DOI":"10.1167\/iovs.16-19313","article-title":"Residual foveal cone structure in CNGB3-associated achromatopsia","volume":"57","author":"Langlo","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib70","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1093\/geronj\/5.3.216","article-title":"Age changes in pupil size","volume":"5","author":"Birren","year":"1950","journal-title":"J Gerontol"},{"issue":"8","key":"bib71","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1167\/tvst.9.8.41","article-title":"Imaging of age-related macular degeneration by adaptive optics scanning laser ophthalmoscopy in eyes with aged lenses or intraocular lenses","volume":"9","author":"Zhang","year":"2020","journal-title":"Transl Vis Sci Technol"},{"key":"bib72","doi-asserted-by":"publisher","first-page":"4679","DOI":"10.1167\/iovs.08-2135","article-title":"Individual variations in human cone photoreceptor packing density: variations with refractive error","volume":"49","author":"Chui","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib73","doi-asserted-by":"publisher","first-page":"104517","DOI":"10.1016\/j.pdpdt.2025.104517","article-title":"Cone mosaic in eyes with varied axial length using adaptive optics scanning laser ophthalmoscopy","volume":"52","author":"Zhou","year":"2025","journal-title":"Photodiagn Photodyn Ther"},{"key":"bib74","doi-asserted-by":"publisher","first-page":"1647","DOI":"10.1364\/BOE.3.001647","article-title":"Adaptive optics scanning ophthalmoscopy with annular pupils","volume":"3","author":"Sulai","year":"2012","journal-title":"Biomed Opt Express"},{"key":"bib24","first-page":"201","article-title":"Automated iterative label transfer improves segmentation of noisy cells in adaptive optics retinal images","volume-title":"Lecture Notes in Computer Science","author":"Liu","year":"2021"},{"key":"bib27","first-page":"153","article-title":"Accurate correspondence of cone photoreceptor neurons in the human eye using graph matching applied to longitudinal adaptive optics images","volume-title":"Lecture Notes in Computer Science","author":"Liu","year":"2017"},{"key":"bib29","first-page":"86","article-title":"Deriving visual cues from deep learning to achieve subpixel cell segmentation in adaptive optics retinal images","volume-title":"Lecture Notes in Computer Science","author":"Liu","year":"2019"},{"key":"bib30","first-page":"201","article-title":"Active appearance model induced generative adversarial network for controlled data augmentation","volume-title":"Lectures in Computer Science","author":"Liu","year":"2019"},{"key":"bib43","volume-title":"American National Standard for ophthalmics\u2013Light Hazard Protection for Ophthalmic Instruments Z80.36","year":"2021"},{"key":"bib47","first-page":"60","volume-title":"Registration of 2D images from fast scanning ophthalmic instruments","author":"Dubra","year":"2010"}],"container-title":["Investigative Ophthalmology & Visual Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.67.10.47","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:20Z","timestamp":1791927140000},"score":1,"resource":{"primary":{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.67.10.47"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,19]]},"references-count":74,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2026,8,3]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.67.10.47","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8,19]]}}}