{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T22:01:59Z","timestamp":1791928919019,"version":"4.3.4"},"reference-count":36,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"8","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Invest. Ophthalmol. Vis. Sci."],"published-print":{"date-parts":[[2026,7,23]]},"DOI":"10.1167\/iovs.67.8.35","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T14:33:14Z","timestamp":1784039594000},"page":"35","source":"Crossref","is-referenced-by-count":0,"title":["Differences in Posterior Ocular Morphology Following Red Light Therapy Versus 0.01% Atropine for Myopia Control: A Randomized Controlled Trial Analysis"],"prefix":"10.1167","volume":"67","author":[{"given":"Ziwei","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Song","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingge","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Shenzhen Nanshan People's Hospital, Shenzhen, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yueye","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoyu","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanjun","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinying","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Peking University Shenzhen Hospital, Shenzhen, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingguang","family":"He","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Centre for Eye and Vision Research (CEVR), Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanxian","family":"Chen","sequence":"additional","affiliation":[{"name":"School of Optometry, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"},{"name":"Research Centre for SHARP Vision, The Hong Kong Polytechnic University, Hong Kong SAR, People's Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","first-page":"101577","article-title":"Myopia and high myopia trends in Chinese children and adolescents over 25 years: a nationwide study with projections to 2050","volume":"59","author":"Pan","year":"2025","journal-title":"Lancet Reg Health West Pac"},{"issue":"10","key":"bib2","doi-asserted-by":"publisher","first-page":"728","DOI":"10.2471\/BLT.12.104034","article-title":"Global cost of correcting vision impairment from uncorrected refractive error","volume":"90","author":"Fricke","year":"2012","journal-title":"Bull World Health Organ"},{"issue":"13","key":"bib3","doi-asserted-by":"publisher","first-page":"5455","DOI":"10.1167\/iovs.18-24754","article-title":"Time-course change in eye shape and development of staphyloma in highly myopic eyes","volume":"59","author":"Wakazono","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib4","doi-asserted-by":"publisher","first-page":"28","DOI":"10.1167\/iovs.63.9.28","article-title":"Quantification and predictors of OCT-based macular curvature and dome-shaped configuration: results from the UK Biobank","volume":"63","author":"M\u00fcller","year":"2022","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib5","doi-asserted-by":"publisher","first-page":"4594","DOI":"10.1038\/s41598-018-22759-y","article-title":"Prevalence of posterior staphyloma and factors associated with its shape in the Japanese population","volume":"8","author":"Numa","year":"2018","journal-title":"Sci Rep"},{"issue":"7","key":"bib6","doi-asserted-by":"publisher","first-page":"1909","DOI":"10.1007\/s40123-024-00956-5","article-title":"Assessment of OCT-based macular curvature and its relationship with macular microvasculature in children with anisomyopia","volume":"13","author":"Wu","year":"2024","journal-title":"Ophthalmol Ther"},{"issue":"2","key":"bib7","doi-asserted-by":"publisher","first-page":"e167","DOI":"10.1111\/aos.15234","article-title":"Clinical characteristics and risk factors of myopic retinoschisis in an elderly high myopia population","volume":"101","author":"Li","year":"2023","journal-title":"Acta Ophthalmol (Copenh)"},{"issue":"5","key":"bib8","doi-asserted-by":"publisher","first-page":"923","DOI":"10.1038\/s41433-023-02804-5","article-title":"Association of macular outward scleral height with axial length, macular choroidal thickness and morphologic characteristics of the optic disc in Chinese adults","volume":"38","author":"Li","year":"2024","journal-title":"Eye"},{"issue":"6","key":"bib9","doi-asserted-by":"publisher","first-page":"1599","DOI":"10.3390\/jcm11061599","article-title":"Association between different grades of myopic tractional maculopathy and OCT-based macular scleral deformation","volume":"11","author":"Feng","year":"2022","journal-title":"J Clin Med"},{"issue":"8","key":"bib10","doi-asserted-by":"publisher","first-page":"1041","DOI":"10.1111\/aos.17544","article-title":"Multimodal analysis of clinical characteristics associated with myopic retinoschisis","volume":"103","author":"Tian","year":"2025","journal-title":"Acta Ophthalmol (Copenh)"},{"issue":"4","key":"bib11","doi-asserted-by":"publisher","first-page":"470","DOI":"10.1136\/bjo-2024-325704","article-title":"Retinal curvature in Chinese children with myopia measured by ultra-widefield swept-source optical coherence tomography","volume":"109","author":"Wu","year":"2025","journal-title":"Br J Ophthalmol"},{"issue":"4","key":"bib12","doi-asserted-by":"publisher","first-page":"1317","DOI":"10.3390\/jcm12041317","article-title":"Anatomic peculiarities associated with axial elongation of the myopic eye","volume":"12","author":"Jonas","year":"2023","journal-title":"J Clin Med"},{"issue":"3","key":"bib13","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1038\/eye.2012.289","article-title":"Scleral thickness in highly myopic eyes measured by enhanced depth imaging optical coherence tomography","volume":"27","author":"Hayashi","year":"2013","journal-title":"Eye"},{"issue":"10","key":"bib14","doi-asserted-by":"publisher","first-page":"41","DOI":"10.1167\/tvst.13.10.41","article-title":"Automated posterior scleral topography assessment for enhanced staphyloma visualization and quantification with improved maculopathy correlation","volume":"13","author":"Han","year":"2024","journal-title":"Transl Vis Sci Technol"},{"issue":"105","key":"bib15","first-page":"5","article-title":"High myopia and its risks","volume":"32","author":"Williams","year":"2019","journal-title":"Community Eye Health"},{"issue":"10","key":"bib16","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1167\/tvst.11.10.33","article-title":"Efficacy comparison of repeated low-level red light and low-dose atropine for myopia control: a randomized controlled trial","volume":"11","author":"Chen","year":"2022","journal-title":"Transl Vis Sci Technol"},{"issue":"4","key":"bib17","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1167\/tvst.14.4.22","article-title":"Effect of repeated low-level red light versus 0.01% topical atropine on myopia progression: a randomized crossover-controlled trial","volume":"14","author":"Pang","year":"2025","journal-title":"Transl Vis Sci Technol"},{"issue":"7","key":"bib18","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1167\/tvst.11.7.24","article-title":"3D reconstruction of a unitary posterior eye by converging optically corrected optical coherence and magnetic resonance tomography images via 3D CAD","volume":"11","author":"Hwang","year":"2022","journal-title":"Transl Vis Sci Technol"},{"issue":"9","key":"bib19","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1167\/iovs.66.9.37","article-title":"Longitudinal study of changes in retinal curvature and its relationship with myopia shift in Chinese children","volume":"66","author":"Wu","year":"2025","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib20","doi-asserted-by":"publisher","first-page":"286","DOI":"10.1016\/j.ophtha.2022.10.002","article-title":"Longitudinal changes and predictive value of choroidal thickness for myopia control after repeated low-level red-light therapy","volume":"130","author":"Xiong","year":"2023","journal-title":"Ophthalmology"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"104651","DOI":"10.1016\/j.pdpdt.2025.104651","article-title":"Effects on choroid after repeated low-level red-light therapy in preclinical and clinical myopic children: a randomized controlled trial","volume":"54","author":"Wei","year":"2025","journal-title":"Photodiagnosis Photodyn Ther"},{"issue":"10","key":"bib22","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1167\/tvst.13.10.29","article-title":"The effect of repeated low-level red-light therapy on myopia control and choroid","volume":"13","author":"Liu","year":"2024","journal-title":"Transl Vis Sci Technol"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"215","DOI":"10.2147\/OPTH.S441962","article-title":"Photobiomodulation using light-emitting diode (LED) for treatment of retinal diseases","volume":"18","author":"Siqueira","year":"2024","journal-title":"Clin Ophthalmol"},{"issue":"3","key":"bib24","doi-asserted-by":"publisher","first-page":"348","DOI":"10.1109\/JSTQE.2016.2561201","article-title":"Proposed mechanisms of photobiomodulation or low-level light therapy","volume":"22","author":"De Freitas","year":"2016","journal-title":"IEEE J Sel Top Quantum Electron"},{"issue":"10","key":"bib25","doi-asserted-by":"publisher","first-page":"1363","DOI":"10.7150\/ijms.85746","article-title":"Repeated low-level red-light therapy for controlling onset and progression of myopia - a review","volume":"20","author":"Zhu","year":"2023","journal-title":"Int J Med Sci"},{"issue":"9","key":"bib26","doi-asserted-by":"publisher","first-page":"502","DOI":"10.5483\/BMBRep.2023-0059","article-title":"Photobiomodulation therapy activates YAP and triggers proliferation and dedifferentiation of M\u00fcller glia in mammalian retina","volume":"56","author":"Kim","year":"2023","journal-title":"BMB Rep"},{"issue":"3","key":"bib27","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.aopr.2025.04.002","article-title":"From stress to sight: The role of mechanical forces in the retinal diseases","volume":"5","author":"Wu","year":"2025","journal-title":"Adv Ophthalmol Pract Res"},{"issue":"24","key":"bib28","doi-asserted-by":"publisher","first-page":"7498","DOI":"10.3390\/jcm11247498","article-title":"Axial length shortening and choroid thickening in myopic adults treated with repeated low-level red light","volume":"11","author":"Liu","year":"2022","journal-title":"J Clin Med"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"203","DOI":"10.1016\/j.ajo.2024.10.011","article-title":"Axial shortening effects of repeated low-level red-light therapy in children with high myopia: a multicenter randomized controlled trial","volume":"270","author":"Liu","year":"2025","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib30","doi-asserted-by":"publisher","first-page":"3321","DOI":"10.1038\/s41598-023-30500-7","article-title":"Photobiomodulation therapy retarded axial length growth in children with myopia: evidence from a 12-month randomized controlled trial evidence","volume":"13","author":"Zhou","year":"2023","journal-title":"Sci Rep"},{"issue":"2","key":"bib31","doi-asserted-by":"publisher","first-page":"1223","DOI":"10.1007\/s40123-023-00671-7","article-title":"Axial shortening in myopic children after repeated low-level red-light therapy: post hoc analysis of a randomized trial","volume":"12","author":"Wang","year":"2023","journal-title":"Ophthalmol Ther"},{"issue":"14","key":"bib32","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1167\/iovs.61.14.15","article-title":"Effects of atropine treatment on choroidal thickness in myopic children","volume":"61","author":"Ye","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.ajo.2021.12.014","article-title":"The association of choroidal thickening by atropine with treatment effects for myopia: two-year clinical trial of the Low-concentration Atropine for Myopia Progression (LAMP) Study","volume":"237","author":"Yam","year":"2022","journal-title":"Am J Ophthalmol"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"1440180","DOI":"10.3389\/fphar.2024.1440180","article-title":"Effects of atropine on choroidal thickness in myopic children: a meta-analysis","volume":"15","author":"Yang","year":"2024","journal-title":"Front Pharmacol"},{"issue":"5","key":"bib35","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1167\/iovs.65.5.25","article-title":"Retinal changes from hyperopia to myopia: not all diopters are created equal","volume":"65","author":"Yii","year":"2024","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib36","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1007\/s10384-024-01128-5","article-title":"Choroidal thickness in macular, nasal midperiphery, and temporal midperiphery regions and its relationship with axial length and refractive error","volume":"69","author":"Hiraoka","year":"2025","journal-title":"Jpn J Ophthalmol"}],"container-title":["Investigative Ophthalmology &amp; Visual Science"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.67.8.35","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:32:18Z","timestamp":1791927138000},"score":1,"resource":{"primary":{"URL":"http:\/\/iovs.arvojournals.org\/article.aspx?doi=10.1167\/iovs.67.8.35"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,23]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2026,7,1]]}},"URL":"https:\/\/doi.org\/10.1167\/iovs.67.8.35","relation":{},"ISSN":["1552-5783"],"issn-type":[{"value":"1552-5783","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7,23]]}}}