{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,12]],"date-time":"2025-11-12T14:12:57Z","timestamp":1762956777754},"reference-count":34,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"14","license":[{"start":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T00:00:00Z","timestamp":1639440000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2021,12,14]]},"DOI":"10.1167\/tvst.10.14.12","type":"journal-article","created":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T17:04:26Z","timestamp":1639501466000},"page":"12","source":"Crossref","is-referenced-by-count":6,"title":["Anti-NOGO Antibody Neuroprotection in a Rat Model of NAION"],"prefix":"10.1167","volume":"10","author":[{"given":"Mary A.","family":"Johnson","sequence":"first","affiliation":[{"name":"Department of Ophthalmology & Visual Science, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zara","family":"Mehrabian","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology & Visual Science, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology & Visual Science, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joy","family":"Ghosh","sequence":"additional","affiliation":[{"name":"Eventide Asset Management, LLC, Boston, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitchell G.","family":"Brigell","sequence":"additional","affiliation":[{"name":"Aerpio Corporation, Belmont, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven L.","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology & Visual Science, University of Maryland School of Medicine, Baltimore, MD, USA"},{"name":"Department of Anatomy and Pathology, University of Maryland School of Medicine, Baltimore, MD, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"2031","DOI":"10.1016\/S0161-6420(03)00804-2","article-title":"The morphology of an infarct in nonarteritic anterior ischemic optic neuropathy","volume":"110","author":"Tesser","year":"2003","journal-title":"Ophthalmology"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0002-9394(14)70999-7","article-title":"Incidence of nonarteritic anterior ischemic optic neuropathy","volume":"123","author":"Hattenhauer","year":"1997","journal-title":"Am J Ophthalmol"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1097\/00041327-199403000-00011","article-title":"Incidence of nonarteritic and arteritic anterior ischemic optic neuropathy. Population-based study in the state of Missouri and Los Angeles County, California","volume":"14","author":"Johnson","year":"1994","journal-title":"J Neuroophthalmol"},{"key":"bib4","first-page":"1422","article-title":"Time course of oligodendrocyte death after rAION in Sprague-Dawley rats","volume":"54","author":"Mehrabyan","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"317","DOI":"10.1016\/S0002-9394(02)01639-2","article-title":"The fellow eye in NAION: report from the ischemic optic neuropathy decompression trial follow-up study","volume":"134","author":"Newman","year":"2002","journal-title":"Am J Ophthalmol"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"4153","DOI":"10.1167\/iovs.03-0274","article-title":"Functional and cellular responses in a novel rodent model of anterior ischemic optic neuropathy","volume":"44","author":"Bernstein","year":"2003","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"2985","DOI":"10.1167\/iovs.07-1651","article-title":"A primate model of nonarteritic anterior ischemic optic neuropathy","volume":"49","author":"Chen","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.preteyeres.2011.02.003","article-title":"Nonarteritic anterior ischemic optic neuropathy (NAION) and its experimental models","volume":"30","author":"Bernstein","year":"2011","journal-title":"Prog Retin Eye Res"},{"issue":"6","key":"bib9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1167\/tvst.8.6.47","article-title":"Topical trabodenoson is neuroprotective in a rodent model of anterior ischemic optic neuropathy (rNAION).","volume":"8","author":"Guo","year":"2019","journal-title":"Transl Vis Sci Technol."},{"issue":"12","key":"bib10","doi-asserted-by":"publisher","first-page":"e50021","DOI":"10.1371\/journal.pone.0050021","article-title":"PGJ(2) provides prolonged CNS stroke protection by reducing white matter edema","volume":"7","author":"Nicholson","year":"2012","journal-title":"PloS One"},{"issue":"1","key":"bib11","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.conb.2004.01.004","article-title":"NOGO and axon regeneration.","volume":"14","author":"Schwab","year":"2004","journal-title":"Curr Opin Neurobiol."},{"issue":"6768","key":"bib12","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1038\/35000219","article-title":"Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1","volume":"403","author":"Chen","year":"2000","journal-title":"Nature"},{"issue":"6818","key":"bib13","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1038\/35053072","article-title":"Identification of a receptor mediating Nogo-66 inhibition of axonal regeneration","volume":"409","author":"Fournier","year":"2001","journal-title":"Nature"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1016\/S0079-6123(02)37027-4","article-title":"Nogo and the Nogo-66 receptor","volume":"137","author":"Fournier","year":"2002","journal-title":"Prog Brain Res"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"706","DOI":"10.1002\/(ISSN)1531-8249","article-title":"Nogo-A antibody improves regeneration and locomotion of spinal cord-injured rats","volume":"58","author":"Liebscher","year":"2005","journal-title":"Ann Neurol"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"6825","DOI":"10.1523\/JNEUROSCI.6239-09.2010","article-title":"MAG and OMgp synergize with Nogo-A to restrict axonal growth and neurological recovery after spinal cord trauma","volume":"30","author":"Cafferty","year":"2010","journal-title":"J Neurosci"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"186","DOI":"10.1161\/STROKEAHA.110.590083","article-title":"Delayed anti-nogo-a therapy improves function after chronic stroke in adult rats","volume":"42","author":"Tsai","year":"2011","journal-title":"Stroke"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"950","DOI":"10.1002\/(ISSN)1531-8249","article-title":"Recovery and brain reorganization after stroke in adult and aged rats","volume":"58","author":"Markus","year":"2005","journal-title":"Ann Neurol"},{"issue":"Pt 3","key":"bib19","doi-asserted-by":"crossref","first-page":"739","DOI":"10.1093\/brain\/awt336","article-title":"Rewiring of the corticospinal tract in the adult rat after unilateral stroke and anti-Nogo-A therapy","volume":"137","author":"Lindau","year":"2014","journal-title":"Brain"},{"issue":"5","key":"bib20","doi-asserted-by":"publisher","first-page":"e0196565","DOI":"10.1371\/journal.pone.0196565","article-title":"Nogo receptor 1 is expressed by nearly all retinal ganglion cells","volume":"13","author":"Solomon","year":"2018","journal-title":"PloS One"},{"key":"bib21","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.1167\/iovs.14-15472","article-title":"Intravitreal delivery of human NgR-Fc decoy protein regenerates axons after optic nerve crush and protects ganglion cells in glaucoma models","volume":"56","author":"Wang","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib22","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1007\/s00429-014-0909-3","article-title":"Nogo-A deletion increases the plasticity of the optokinetic response and changes retinal projection organization in the adult mouse visual system","volume":"221","author":"Guzik-Kornacka","year":"2016","journal-title":"Brain Struct Funct"},{"key":"bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s10633-014-9473-7","article-title":"ISCEV Standard for full-field clinical electroretinography (2015 update)","volume":"130","author":"McCulloch","year":"2015","journal-title":"Doc Ophthalmol"},{"issue":"8","key":"bib24","doi-asserted-by":"crossref","first-page":"e0148855","DOI":"10.1371\/journal.pone.0148855","article-title":"SUR1-associated mechanisms are not involved in ischemic optic neuropathy 1 day post-injury","volume":"11","author":"Nicholson","year":"2016","journal-title":"PloS One"},{"issue":"8","key":"bib25","doi-asserted-by":"crossref","first-page":"3671","DOI":"10.1167\/iovs.07-0504","article-title":"Rodent anterior ischemic optic neuropathy (rAION) induces regional retinal ganglion cell apoptosis with a unique temporal pattern","volume":"49","author":"Slater","year":"2008","journal-title":"Investigative Ophthalmology & Visual Science"},{"issue":"1","key":"bib26","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jneumeth.2007.12.008","article-title":"Efficient estimation of retinal ganglioon cell number: A stereological approach.","volume":"170","author":"Fileta","year":"2008","journal-title":"J Neurosci Methods."},{"issue":"52","key":"bib27","doi-asserted-by":"crossref","first-page":"E8453","DOI":"10.1073\/pnas.1615322113","article-title":"Nogo receptor blockade overcomes remyelination failure after white matter stroke and stimulates functional recovery in aged mice","volume":"113","author":"Sozmen","year":"2016","journal-title":"Proc Natl Acad Sci USA."},{"key":"bib28","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1038\/s41419-020-2302-x","article-title":"Nogo-A-targeting antibody promotes visual recovery and inhibits neuroinflammation after retinal injury","volume":"11","author":"Baya Mdzomba","year":"2020","journal-title":"Cell Death Dis"},{"key":"bib29","doi-asserted-by":"crossref","first-page":"14270","DOI":"10.1073\/pnas.1905309116","article-title":"Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke","volume":"116","author":"Rust","year":"2019","journal-title":"Proc Natl Acad Sci USA."},{"key":"bib30","doi-asserted-by":"crossref","DOI":"10.1007\/s10571-021-01124-0","article-title":"A novel role of NOGO Proteins: regulating macrophages in inflammatory disease.","author":"Zhang","year":"2021","journal-title":"Cell Mol Neurobiol."},{"key":"bib31","doi-asserted-by":"crossref","first-page":"e0243186","DOI":"10.1371\/journal.pone.0243186","article-title":"Biomarkers of lesion severity in a rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION)","volume":"16","author":"Guo","year":"2021","journal-title":"PloS One"},{"key":"bib32","doi-asserted-by":"crossref","first-page":"7402","DOI":"10.1167\/iovs.13-12055","article-title":"Sustained neuroprotection from a single intravitreal injection of PGJ2 in a rodent model of anterior ischemic optic neuropathy","volume":"54","author":"Touitou","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib33","doi-asserted-by":"crossref","first-page":"7047","DOI":"10.1167\/iovs.14-14063","article-title":"Sustained neuroprotection from a single intravitreal injection of PGJ2 in a nonhuman primate model of nonarteritic anterior ischemic optic neuropathy","volume":"55","author":"Miller","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib34","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1167\/iovs.15-17880","article-title":"Peripapillary retinal nerve fiber layer swelling predicts peripapillary atrophy in a primate model of nonarteritic anterior ischemic optic neuropathy","volume":"57","author":"Johnson","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2778157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,12,14]],"date-time":"2021-12-14T17:04:36Z","timestamp":1639501476000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2778157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,14]]},"references-count":34,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2021,12,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.10.14.12","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12,14]]}}}