{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T00:40:07Z","timestamp":1781656807130,"version":"3.54.5"},"reference-count":23,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"4","license":[{"start":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T00:00:00Z","timestamp":1619654400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2021,4,29]]},"DOI":"10.1167\/tvst.10.4.33","type":"journal-article","created":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T16:31:38Z","timestamp":1619713898000},"page":"33","source":"Crossref","is-referenced-by-count":10,"title":["The Influence of Cataract on Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO)"],"prefix":"10.1167","volume":"10","author":[{"given":"Joel-Benjamin","family":"Lincke","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chantal","family":"Dysli","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Damian","family":"Jaggi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahel","family":"Fink","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebastian","family":"Wolf","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin S.","family":"Zinkernagel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"4-6","key":"bib1","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1023\/A:1014475219117","article-title":"Basic investigations for 2-dimensional time-resolved fluorescence measurements at the fundus","volume":"23","author":"Schweitzer","year":"2001","journal-title":"Int Ophthalmol"},{"issue":"6","key":"bib2","doi-asserted-by":"publisher","first-page":"1214","DOI":"10.1117\/1.1806833","article-title":"In vivo measurement of time-resolved autofluorescence at the human fundus","volume":"9","author":"Schweitzer","year":"2004","journal-title":"J Biomed Opt"},{"issue":"5","key":"bib3","doi-asserted-by":"publisher","first-page":"410","DOI":"10.1002\/(ISSN)1097-0029","article-title":"Towards metabolic mapping of the human retina","volume":"70","author":"Schweitzer","year":"2007","journal-title":"Microsc Res Tech"},{"issue":"4","key":"bib4","doi-asserted-by":"publisher","first-page":"2106","DOI":"10.1167\/iovs.13-13627","article-title":"Quantitative analysis of fluorescence lifetime measurements of the macula using the fluorescence lifetime imaging ophthalmoscope in healthy subjects","volume":"55","author":"Dysli","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"bib5","doi-asserted-by":"publisher","first-page":"3329","DOI":"10.1167\/iovs.14-16203","article-title":"Fluorescence lifetime imaging in retinal artery occlusion","volume":"56","author":"Dysli","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib6","doi-asserted-by":"publisher","first-page":"195","DOI":"10.1159\/000503567","article-title":"Fluorescence lifetime patterns of retinal pigment epithelium atrophy in patients with stargardt disease and age-related macular degeneration","volume":"243","author":"Solberg","year":"2020","journal-title":"Ophthalmologica"},{"issue":"6","key":"bib7","doi-asserted-by":"publisher","first-page":"2165","DOI":"10.1167\/iovs.18-26079","article-title":"Fluorescence lifetimes in patients with hydroxychloroquine retinopathy","volume":"60","author":"Solberg","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"bib8","doi-asserted-by":"publisher","first-page":"879","DOI":"10.1097\/IAE.0000000000002519","article-title":"Retinal flecks in Stargardt disease reveal characteristic fluorescence lifetime transition over time","volume":"39","author":"Solberg","year":"2019","journal-title":"Retina"},{"issue":"3","key":"bib9","doi-asserted-by":"publisher","first-page":"832","DOI":"10.1167\/iovs.15-18033","article-title":"Fluorescence lifetime imaging in Stargardt disease: potential marker for disease progression","volume":"57","author":"Dysli","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"bib10","doi-asserted-by":"publisher","first-page":"61106","DOI":"10.1117\/1.JBO.20.6.061106","article-title":"Fluorescence lifetime imaging ophthalmoscopy in type 2 diabetic patients who have no signs of diabetic retinopathy","volume":"20","author":"Schweitzer","year":"2015","journal-title":"J Biomed Opt"},{"issue":"8","key":"bib11","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1038\/s41433-019-0406-2","article-title":"A pilot study of fluorescence lifetime imaging ophthalmoscopy in preclinical Alzheimer's disease","volume":"33","author":"Sadda","year":"2019","journal-title":"Eye"},{"issue":"10","key":"bib12","doi-asserted-by":"publisher","first-page":"1929","DOI":"10.1097\/IAE.0000000000002718","article-title":"Fluorescence lifetime imaging ophthalmoscopy findings after surgical reattachment of macula-off rhegmatogenous retinal detachment","volume":"40","author":"Jaggi","year":"2020","journal-title":"Retina"},{"issue":"12","key":"bib13","doi-asserted-by":"publisher","first-page":"e0209194","DOI":"10.1371\/journal.pone.0209194","article-title":"Impact of mydriasis in fluorescence lifetime imaging ophthalmoscopy","volume":"13","author":"Sadda","year":"2018","journal-title":"PLoS One"},{"issue":"5 suppl","key":"bib14","first-page":"741","article-title":"Early Treatment Diabetic Retinopathy Study design and baseline patient characteristics: ETDRS report number 7","volume":"98","year":"1991","journal-title":"Ophthalmology"},{"issue":"3","key":"bib15","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1167\/tvst.8.3.15","article-title":"Repeatability of fluorescence lifetime imaging ophthalmoscopy in normal subjects with mydriasis","volume":"8","author":"Kwon","year":"2019","journal-title":"Transl Vis Sci Technol"},{"issue":"6","key":"bib16","doi-asserted-by":"publisher","first-page":"831","DOI":"10.1001\/archopht.1993.01090060119035","article-title":"The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group","volume":"111","author":"Chylack","year":"1993","journal-title":"Arch Ophthalmol"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"190","DOI":"10.1016\/j.exer.2013.08.014","article-title":"Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance","volume":"116","author":"Dennison","year":"2013","journal-title":"Exp Eye Res"},{"issue":"9","key":"bib18","doi-asserted-by":"publisher","first-page":"3616","DOI":"10.1167\/iovs.17-21818","article-title":"Correlations between macular, skin, and serum carotenoids","volume":"58","author":"Conrady","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"bib19","doi-asserted-by":"publisher","first-page":"4076","DOI":"10.1167\/iovs.12-9471","article-title":"Spectral transmission of the human crystalline lens in adult and elderly persons: color and total transmission of visible light","volume":"53","author":"Artigas","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"bib20","doi-asserted-by":"publisher","first-page":"e0131640","DOI":"10.1371\/journal.pone.0131640","article-title":"FLIMX: a software package to determine and analyze the fluorescence lifetime in time-resolved fluorescence data from the human eye","volume":"10","author":"Klemm","year":"2015","journal-title":"PLoS One"},{"issue":"9","key":"bib21","doi-asserted-by":"publisher","first-page":"263","DOI":"10.1515\/BMT.2005.038","article-title":"Limits of the confocal laser-scanning technique in measurements of time-resolved autofluorescence of the ocular fundus","volume":"50","author":"Schweitzer","year":"2005","journal-title":"Biomed Tech (Berl)"},{"issue":"9","key":"bib22","doi-asserted-by":"publisher","first-page":"3198","DOI":"10.1364\/BOE.7.003198","article-title":"Combination of confocal principle and aperture stop separation improves suppression of crystalline lens fluorescence in an eye model","volume":"7","author":"Klemm","year":"2016","journal-title":"Biomed Opt Express"},{"issue":"8","key":"bib23","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1167\/tvst.9.8.13","article-title":"Influence of lens fluorescence on fluorescence lifetime imaging ophthalmoscopy (FLIO) fundus imaging and strategies for its compensation","volume":"9","author":"Brauer","year":"2020","journal-title":"Transl Vis Sci Technol"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2772542","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,29]],"date-time":"2021-04-29T16:31:41Z","timestamp":1619713901000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2772542"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4,29]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2021,4,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.10.4.33","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2021,4,29]]}}}