{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T06:10:20Z","timestamp":1789711820463,"version":"4.0.1"},"reference-count":36,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"8","license":[{"start":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T00:00:00Z","timestamp":1626652800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2021,7,19]]},"DOI":"10.1167\/tvst.10.8.18","type":"journal-article","created":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T15:31:12Z","timestamp":1626708672000},"page":"18","source":"Crossref","is-referenced-by-count":8,"title":["Evaluation of Primary Pterygia on Basis of the Loss of Vertical Length of Plica Semilunaris"],"prefix":"10.1167","volume":"10","author":[{"given":"Minjeong","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yeoun Sook","family":"Chun","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoung Woo","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Chung-Ang University College of Medicine, Seoul, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1016\/j.exer.2015.01.010","article-title":"Fibroblast biology in pterygia","volume":"142","author":"Kim","year":"2016","journal-title":"Exp Eye Res"},{"key":"bib2","first-page":"1687","article-title":"Expression of cell proliferation and apoptosis biomarkers in pterygia and normal conjunctiva","volume":"17","author":"Liang","year":"2011","journal-title":"Mol Vis"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1136\/bjo.84.2.212","article-title":"Apoptosis and apoptosis related gene expression in normal conjunctiva and pterygium","volume":"84","author":"Tan","year":"2000","journal-title":"Br J Ophthalmol"},{"key":"bib4","first-page":"635","article-title":"Cyclooxygenase 2 expression in pterygium","volume":"13","author":"Chiang","year":"2007","journal-title":"Mol Vis"},{"key":"bib5","first-page":"3430","article-title":"UVB-mediated induction of interleukin-6 and -8 in pterygia and cultured human pterygium epithelial cells","volume":"43","author":"Di Girolamo","year":"2002","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1076\/ocii.11.2.115.15913","article-title":"The roles of T-lymphocyte subpopulations (CD4 and CD8), intercellular adhesion molecule-1 (ICAM-1), HLA-DR receptor, and mast cells in etiopathogenesis of pterygium","volume":"11","author":"Beden","year":"2003","journal-title":"Ocul Immunol Inflamm"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1038\/sj.eye.6702064","article-title":"Increased oxidative DNA damage, 8-hydroxydeoxy- guanosine, in human pterygium","volume":"20","author":"Kau","year":"2006","journal-title":"Eye (Lond)"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"332","DOI":"10.1007\/s00417-003-0846-y","article-title":"Distribution of extracellular matrix proteins in pterygia: an immunohistochemical study","volume":"242","author":"Naib-Majani","year":"2004","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"782","DOI":"10.1136\/bjo.85.7.782","article-title":"Human papillomavirus in pterygium","volume":"85","author":"Gallagher","year":"2001","journal-title":"Br J Ophthalmol"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"164","DOI":"10.1097\/00003226-200103000-00010","article-title":"Detection of herpes simplex virus and human papilloma virus in ophthalmic pterygium","volume":"20","author":"Detorakis","year":"2001","journal-title":"Cornea"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1016\/S1542-0124(12)70103-9","article-title":"The pathogenesis of pterygium: current concepts and their therapeutic implications","volume":"6","author":"Chui","year":"2008","journal-title":"Ocul Surf"},{"key":"bib12","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/BF02632046","article-title":"Fibroblasts isolated from human pterygia exhibit transformed cell characteristics","volume":"30A","author":"Chen","year":"1994","journal-title":"In Vitro Cell Dev Biol Anim"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"7198","DOI":"10.1167\/iovs.13-13044","article-title":"Upregulated stromal cell-derived factor 1 (SDF-1) expression and its interaction with CXCR4 contribute to the pathogenesis of severe pterygia","volume":"54","author":"Kim","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"6355","DOI":"10.1167\/iovs.13-12141","article-title":"Overexpression of angiogenin in pterygium body fibroblasts and its association with proliferative potency","volume":"54","author":"Kim","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1016\/j.exer.2017.08.008","article-title":"TNF-alpha upregulates HIF-1alpha expression in pterygium fibroblasts and enhances their susceptibility to VEGF independent of hypoxia","volume":"164","author":"Kim","year":"2017","journal-title":"Exp Eye Res"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"1235","DOI":"10.1001\/archopht.1997.01100160405001","article-title":"Effect of pterygium morphology on pterygium recurrence in a controlled trial comparing conjunctival autografting with bare sclera excision","volume":"115","author":"Tan","year":"1997","journal-title":"Arch Ophthalmol"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1001\/archophthalmol.2011.328","article-title":"New grading system to improve the surgical outcome of multirecurrent pterygia","volume":"130","author":"Liu","year":"2012","journal-title":"Arch Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"2300","DOI":"10.1016\/j.ophtha.2016.07.028","article-title":"Matrix metalloproteinase 9 testing in dry eye disease using a commercially available point-of-care immunoassay","volume":"123","author":"Messmer","year":"2016","journal-title":"Ophthalmology"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1016\/j.exer.2006.02.004","article-title":"Corticosteroid and doxycycline suppress MMP-9 and inflammatory cytokine expression, MAPK activation in the corneal epithelium in experimental dry eye","volume":"83","author":"De Paiva","year":"2006","journal-title":"Exp Eye Res"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"4588","DOI":"10.1167\/iovs.08-3147","article-title":"Increased expression of gelatinase (MMP-2 and MMP-9) in pterygia and pterygium fibroblasts with disease progression and activation of protein kinase C","volume":"50","author":"Yang","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.jtos.2017.05.001","article-title":"TFOS DEWS II Diagnostic Methodology report","volume":"15","author":"Wolffsohn","year":"2017","journal-title":"Ocul Surf"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"812","DOI":"10.1097\/ICO.0000000000000175","article-title":"Prospective, multicenter, clinical evaluation of point-of-care matrix metalloproteinase-9 test for confirming dry eye disease","volume":"33","author":"Sambursky","year":"2014","journal-title":"Cornea"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1001\/jamaophthalmol.2013.561","article-title":"Sensitivity and specificity of a point-of-care matrix metalloproteinase 9 immunoassay for diagnosing inflammation related to dry eye","volume":"131","author":"Sambursky","year":"2013","journal-title":"JAMA Ophthalmol"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1167\/tvst.7.5.31","article-title":"Matrix metalloproteinase 9 point-of-care immunoassay result predicts response to topical cyclosporine treatment in dry eye disease","volume":"7","author":"Park","year":"2018","journal-title":"Transl Vis Sci Technol"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1097\/00003226-199801000-00007","article-title":"Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation","volume":"17","author":"Pflugfelder","year":"1998","journal-title":"Cornea"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"2006","DOI":"10.1167\/iovs.10-6997f","article-title":"The international workshop on meibomian gland dysfunction: report of the diagnosis subcommittee","volume":"52","author":"Tomlinson","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"Pt 4","key":"bib27","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/eye.1991.65","article-title":"Meibomian gland disease. Classification and grading of lid changes","volume":"5","author":"Bron","year":"1991","journal-title":"Eye (Lond)"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"3462","DOI":"10.1167\/iovs.09-4921","article-title":"Effect of TIMP-1 and MMP in pterygium invasion","volume":"51","author":"Tsai","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"4523","DOI":"10.21873\/anticanres.14457","article-title":"The contribution of MMP-9 genotypes to pterygium in Taiwan","volume":"40","author":"Tsai","year":"2020","journal-title":"Anticancer Res"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"108194","DOI":"10.1016\/j.exer.2020.108194","article-title":"Relative gene expression analysis of human pterygium tissues and UV radiation-evoked gene expression patterns in corneal and conjunctival cells","volume":"199","author":"Shibata","year":"2020","journal-title":"Exp Eye Res"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"694","DOI":"10.1136\/bjophthalmol-2012-302784","article-title":"Management of complicated multirecurrent pterygia using multimicroporous expanded polytetrafluoroethylene","volume":"97","author":"Kim","year":"2013","journal-title":"Br J Ophthalmol"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"1278","DOI":"10.1016\/j.ophtha.2009.01.044","article-title":"Recurrent pterygium surgery using pterygium extended removal followed by extended conjunctival transplant: recurrence rate and cosmesis","volume":"116","author":"Hirst","year":"2009","journal-title":"Ophthalmology"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.jtos.2012.07.002","article-title":"Wakayama symposium: challenges of future research in ocular surface cell biology","volume":"11","author":"Kao","year":"2013","journal-title":"Ocul Surf"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"315","DOI":"10.1159\/000150445","article-title":"Inflammatory markers in the tears of patients with ocular surface disease","volume":"40","author":"Acera","year":"2008","journal-title":"Ophthalmic Res"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"3203","DOI":"10.1167\/iovs.08-2476","article-title":"Production and activity of matrix metalloproteinase-9 on the ocular surface increase in dysfunctional tear syndrome","volume":"50","author":"Chotikavanich","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"62","DOI":"10.1016\/j.ophtha.2014.07.048","article-title":"Matrix metalloproteinase 9 and transglutaminase 2 expression at the ocular surface in patients with different forms of dry eye disease","volume":"122","author":"Aragona","year":"2015","journal-title":"Ophthalmology"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2776483","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,7,19]],"date-time":"2021-07-19T15:31:21Z","timestamp":1626708681000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2776483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,19]]},"references-count":36,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2021,7,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.10.8.18","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2021,7,19]]}}}