{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T04:29:26Z","timestamp":1791606566117,"version":"4.3.4"},"reference-count":84,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"10","license":[{"start":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T00:00:00Z","timestamp":1665705600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2022,10,14]]},"DOI":"10.1167\/tvst.11.10.22","type":"journal-article","created":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T11:35:40Z","timestamp":1665747340000},"page":"22","source":"Crossref","is-referenced-by-count":19,"title":["In Situ-Forming Collagen-Hyaluronate Semi-Interpenetrating Network Hydrogel Enhances Corneal Defect Repair"],"prefix":"10.1167","volume":"11","author":[{"given":"Fang","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"},{"name":"VA Palo Alto HealthCare System, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David C.","family":"Mundy","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter","family":"Le","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"},{"name":"VA Palo Alto HealthCare System, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngyoon Amy","family":"Seo","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin M.","family":"Logan","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gabriella Maria","family":"Fernandes-Cunha","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris A.","family":"Basco","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Myung","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, CA, USA"},{"name":"VA Palo Alto HealthCare System, Palo Alto, CA, USA"},{"name":"Department of Chemical Engineering, Stanford University, Palo Alto, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"2","key":"bib1","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1001\/jamaophthalmol.2015.4776","article-title":"Global survey of corneal transplantation and eye banking","volume":"134","author":"Gain","year":"2016","journal-title":"JAMA Ophthalmol"},{"issue":"12","key":"bib2","doi-asserted-by":"publisher","first-page":"2432","DOI":"10.1016\/j.ophtha.2015.08.017","article-title":"Keratoplasty in the United States","volume":"122","author":"Park","year":"2015","journal-title":"Ophthalmology"},{"key":"bib3","author":"EBAA","year":"2021","journal-title":"Eye Bank statistical report \u2013 2020"},{"issue":"10","key":"bib4","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1136\/bjophthalmol-2017-311643","article-title":"Surgical adhesives in ophthalmology: history and current trends","volume":"102","author":"Guhan","year":"2018","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"bib5","doi-asserted-by":"publisher","first-page":"668","DOI":"10.1097\/ICO.0000000000001919","article-title":"Outcomes of cyanoacrylate tissue adhesive application in corneal thinning and perforation","volume":"38","author":"Yin","year":"2019","journal-title":"Cornea"},{"issue":"12","key":"bib6","doi-asserted-by":"publisher","first-page":"e1221","DOI":"10.1016\/S2214-109X(17)30393-5","article-title":"Global causes of blindness and distance vision impairment 1990\u20132020: a systematic review and meta-analysis","volume":"5","author":"Flaxman","year":"2017","journal-title":"Lancet Glob Health"},{"issue":"6","key":"bib7","doi-asserted-by":"publisher","first-page":"834","DOI":"10.1016\/j.stem.2018.05.013","article-title":"Regenerating eye tissues to preserve and restore vision","volume":"22","author":"Stern","year":"2018","journal-title":"Cell Stem Cell"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1016\/j.ajo.2020.11.006","article-title":"Comparative study of long-term graft survival between penetrating keratoplasty and deep anterior lamellar keratoplasty","volume":"224","author":"Arundhati","year":"2021","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"bib9","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1097\/ICO.0000000000000327","article-title":"Clinical outcomes and risk factors for graft failure after deep anterior lamellar keratoplasty and penetrating keratoplasty for macular corneal dystrophy","volume":"34","author":"Reddy","year":"2015","journal-title":"Cornea"},{"issue":"4","key":"bib10","doi-asserted-by":"publisher","first-page":"390","DOI":"10.1097\/ICU.0000000000000373","article-title":"The Boston keratoprosthesis.","volume":"28","author":"Saeed","year":"2017","journal-title":"Curr Opin Ophthalmol"},{"issue":"9","key":"bib11","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1097\/ICO.0b013e3181a186dc","article-title":"Boston keratoprosthesis outcomes and complications.","volume":"28","author":"Chew","year":"2009","journal-title":"Cornea."},{"issue":"4","key":"bib12","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1097\/ICU.0b013e3283477d0d","article-title":"Expanding indications for the Boston keratoprosthesis.","volume":"22","author":"Colby","year":"2011","journal-title":"Curr Opin Ophthalmol."},{"issue":"4","key":"bib13","doi-asserted-by":"publisher","first-page":"1068","DOI":"10.1111\/ajt.13096","article-title":"Lamellar keratoplasty treatment of fungal corneal ulcers with acellular porcine corneal stroma","volume":"15","author":"Zhang","year":"2015","journal-title":"Am J Transplant"},{"issue":"1","key":"bib14","doi-asserted-by":"publisher","first-page":"434","DOI":"10.1186\/s12967-019-02192-z","article-title":"Risk factors influencing survival of acellular porcine corneal stroma in infectious keratitis: a prospective clinical study","volume":"17","author":"Li","year":"2019","journal-title":"J Transl Med"},{"issue":"37","key":"bib15","doi-asserted-by":"publisher","first-page":"1902491","DOI":"10.1002\/adfm.v29.37","article-title":"Protectively decellularized porcine cornea versus human donor cornea for lamellar transplantation","volume":"29","author":"Shi","year":"2019","journal-title":"Adv Funct Mater"},{"issue":"2","key":"bib16","doi-asserted-by":"publisher","first-page":"162","DOI":"10.1111\/cts.2009.2.issue-2","article-title":"Corneal regeneration following implantation of a biomimetic tissue-engineered substitute","volume":"2","author":"Fagerholm","year":"2009","journal-title":"Clin Transl Sci"},{"issue":"46","key":"bib17","doi-asserted-by":"publisher","first-page":"46ra61","DOI":"10.1126\/scitranslmed.3001022","article-title":"A biosynthetic alternative to human donor tissue for inducing corneal regeneration: 24-month follow-up of a phase 1 clinical study","volume":"2","author":"Fagerholm","year":"2010","journal-title":"Sci Transl Med"},{"issue":"8","key":"bib18","doi-asserted-by":"publisher","first-page":"2420","DOI":"10.1016\/j.biomaterials.2013.11.079","article-title":"Stable corneal regeneration four years after implantation of a cell-free recombinant human collagen scaffold","volume":"35","author":"Fagerholm","year":"2014","journal-title":"Biomaterials"},{"issue":"5","key":"bib19","doi-asserted-by":"publisher","first-page":"558","DOI":"10.1111\/cts.2015.8.issue-5","article-title":"Bioengineered corneas grafted as alternatives to human donor corneas in three high-risk patients","volume":"8","author":"Buznyk","year":"2015","journal-title":"Clin Transl Sci"},{"issue":"6","key":"bib20","doi-asserted-by":"publisher","first-page":"604","DOI":"10.1097\/00003226-199511000-00014","article-title":"Corneal neovascularization after penetrating keratoplasty","volume":"14","author":"Dana","year":"1995","journal-title":"Cornea"},{"issue":"3","key":"bib21","doi-asserted-by":"publisher","first-page":"eaav1281","DOI":"10.1126\/sciadv.aav1281","article-title":"Sutureless repair of corneal injuries using naturally derived bioadhesive hydrogels","volume":"5","author":"Shirzaei Sani","year":"2019","journal-title":"Sci Adv"},{"issue":"25","key":"bib22","doi-asserted-by":"publisher","first-page":"eaba2187","DOI":"10.1126\/sciadv.aba2187","article-title":"LiQD Cornea: pro-regeneration collagen mimetics as patches and alternatives to corneal transplantation","volume":"6","author":"McTiernan","year":"2020","journal-title":"Sci Adv"},{"issue":"3","key":"bib23","first-page":"376","article-title":"Human corneal stroma contains three distinct collagens","volume":"22","author":"Newsome","year":"1982","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib24","doi-asserted-by":"publisher","first-page":"16671","DOI":"10.1038\/s41598-020-72978-5","article-title":"In situ-forming collagen hydrogel crosslinked via multi-functional PEG as a matrix therapy for corneal defects","volume":"10","author":"Fernandes-Cunha","year":"2020","journal-title":"Sci Rep"},{"issue":"4","key":"bib25","doi-asserted-by":"publisher","first-page":"481","DOI":"10.1006\/exer.1998.0567","article-title":"Hyaluronan and CD44 in the human cornea and limbal conjunctiva","volume":"67","author":"Lerner","year":"1998","journal-title":"Exp Eye Res"},{"key":"bib26","first-page":"62","article-title":"Hyaluronic acid in tear fluid and its synthesis by corneal epithelial cells","volume":"40","author":"Fukuda","year":"1998","journal-title":"Asia Pac J Ophthalmol"},{"issue":"8","key":"bib27","doi-asserted-by":"publisher","first-page":"511","DOI":"10.3390\/diagnostics10080511","article-title":"Why chain length of hyaluronan in eye drops matters","volume":"10","author":"M\u00fcller-Lierheim","year":"2020","journal-title":"Diagnostics"},{"issue":"5","key":"bib28","doi-asserted-by":"publisher","first-page":"395","DOI":"10.1097\/ICU.0000000000000595","article-title":"Periocular hyaluronic acid fillers: applications, implications, complications","volume":"30","author":"Murthy","year":"2019","journal-title":"Curr Opin Ophthalmol"},{"issue":"6","key":"bib29","doi-asserted-by":"publisher","first-page":"821","DOI":"10.1136\/bjo.2003.027573","article-title":"Sodium hyaluronate (hyaluronic acid) promotes migration of human corneal epithelial cells in vitro","volume":"88","author":"Gomes","year":"2004","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"bib30","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1016\/0014-4835(91)90110-Z","article-title":"Hyaluronan stimulates corneal epithelial migration","volume":"53","author":"Nishida","year":"1991","journal-title":"Exp Eye Res"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2016\/6538051","article-title":"Hyaluronate acid-dependent protection and enhanced corneal wound healing against oxidative damage in corneal epithelial cells","volume":"2016","author":"Zhong","year":"2016","journal-title":"J Ophthalmol"},{"issue":"1","key":"bib32","doi-asserted-by":"publisher","first-page":"2351","DOI":"10.1038\/s41598-021-81983-1","article-title":"Development of a novel hyaluronic acid membrane for the treatment of ocular surface diseases","volume":"11","author":"Kim","year":"2021","journal-title":"Sci Rep"},{"issue":"4","key":"bib33","doi-asserted-by":"publisher","first-page":"460","DOI":"10.1001\/archophthalmol.2009.70","article-title":"Solid hyaluronic acid film and the prevention of postoperative fibrous scar formation in experimental animal eyes","volume":"127","author":"Takeuchi","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"3","key":"bib34","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1111\/(ISSN)1463-5224","article-title":"A cross-linked hyaluronan gel accelerates healing of corneal epithelial abrasion and alkali burn injuries in rabbits","volume":"13","author":"Yang","year":"2010","journal-title":"Vet Ophthalmol"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"120176","DOI":"10.1016\/j.biomaterials.2020.120176","article-title":"Bio-orthogonally crosslinked hyaluronate-collagen hydrogel for suture-free corneal defect repair","volume":"255","author":"Chen","year":"2020","journal-title":"Biomaterials"},{"issue":"12","key":"bib36","doi-asserted-by":"publisher","first-page":"5208","DOI":"10.1021\/acs.chemmater.0c01307","article-title":"Simultaneous interpenetrating polymer network of collagen and hyaluronic acid as an in situ -forming corneal defect filler","volume":"32","author":"Chen","year":"2020","journal-title":"Chem Mater"},{"issue":"12","key":"bib37","doi-asserted-by":"publisher","first-page":"2287","DOI":"10.1351\/pac199668122287","article-title":"Glossary of basic terms in polymer science (IUPAC Recommendations 1996)","volume":"68","author":"Jenkins","year":"1996","journal-title":"Pure Appl Chem"},{"issue":"12","key":"bib38","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1016\/j.jcrs.2014.03.034","article-title":"Hydrogel sealant versus sutures to prevent fluid egress after cataract surgery","volume":"40","author":"Masket","year":"2014","journal-title":"J Cataract Refract Surg"},{"issue":"7","key":"bib39","doi-asserted-by":"publisher","first-page":"2385","DOI":"10.1016\/j.actbio.2009.05.004","article-title":"Photopatterned collagen\u2013hyaluronic acid interpenetrating polymer network hydrogels","volume":"5","author":"Suri","year":"2009","journal-title":"Acta Biomater"},{"issue":"8","key":"bib40","doi-asserted-by":"publisher","first-page":"1105","DOI":"10.1080\/02713683.2020.1868010","article-title":"3D Printable, modified trephine designs for consistent anterior lamellar keratectomy wounds in rabbits","volume":"46","author":"Chen","year":"2021","journal-title":"Curr Eye Res"},{"issue":"3","key":"bib41","doi-asserted-by":"publisher","first-page":"34","DOI":"10.7309\/jmtm","article-title":"Clinical application of a smartphone-based ophthalmic camera adapter in under-resourced settings in Nepal","volume":"6","author":"Mercado","year":"2017","journal-title":"J Mob Technol Med"},{"issue":"9","key":"bib42","doi-asserted-by":"publisher","first-page":"4531","DOI":"10.1167\/iovs.09-5106","article-title":"A quantitative rabbit model of vaccinia keratitis","volume":"51","author":"Altmann","year":"2010","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib43","doi-asserted-by":"publisher","first-page":"367","DOI":"10.1122\/1.549853","article-title":"Analysis of linear viscoelasticity of a crosslinking polymer at the gel point","volume":"30","author":"Winter","year":"1986","journal-title":"J Rheol"},{"issue":"6","key":"bib44","first-page":"776","article-title":"Transmission of the ocular media","volume":"1","author":"Boettner","year":"1962","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib46","doi-asserted-by":"publisher","first-page":"1042","DOI":"10.1097\/ICO.0b013e318172fc40","article-title":"Human cornea before and after refractive surgery using a new device: VCH-1","volume":"27","author":"Patel","year":"2008","journal-title":"Cornea"},{"issue":"2","key":"bib47","doi-asserted-by":"publisher","first-page":"100","DOI":"10.3928\/1081-597X-19950301-09","article-title":"Refractive index of the human corneal epithelium and stroma","volume":"11","author":"Patel","year":"1995","journal-title":"J Refract Surg"},{"issue":"4","key":"bib49","doi-asserted-by":"publisher","first-page":"1184","DOI":"10.1002\/jbm.a.v101a.4","article-title":"Biochemically and topographically engineered poly(ethylene glycol) diacrylate hydrogels with biomimetic characteristics as substrates for human corneal epithelial cells","volume":"101A","author":"Ya\u00f1ez-Soto","year":"2013","journal-title":"J Biomed Mater Res"},{"issue":"4","key":"bib50","doi-asserted-by":"publisher","first-page":"1001","DOI":"10.1242\/jcs.104.4.1001","article-title":"Stromal fibroblasts synthesize collagenase and stromelysin during long-term tissue remodeling","volume":"104","author":"Girard","year":"1993","journal-title":"J Cell Sci"},{"issue":"11","key":"bib51","first-page":"3011","article-title":"Hyaluronic acid in the rabbit cornea after excimer laser superficial keratectomy","volume":"33","author":"Fitzsimmons","year":"1992","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"108460","DOI":"10.1016\/j.jneumeth.2019.108460","article-title":"Optimizing cell encapsulation condition in ECM-Collagen I hydrogels to support 3D neuronal cultures","volume":"329","author":"Lam","year":"2020","journal-title":"J Neurosci Methods"},{"issue":"2","key":"bib53","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1023\/A:1026543900054","article-title":"The earth mover's distance as a metric for image retrieval","volume":"40","author":"Rubner","year":"2000","journal-title":"Int J Comp Vis"},{"issue":"3","key":"bib54","doi-asserted-by":"publisher","first-page":"e0151859","DOI":"10.1371\/journal.pone.0151859","article-title":"Earth mover's distance (EMD): a true metric for comparing biomarker expression levels in cell populations","volume":"11","author":"Orlova","year":"2016","journal-title":"PLoS One"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"108272","DOI":"10.1016\/j.exer.2020.108272","article-title":"Corneal myofibroblasts and fibrosis","volume":"201","author":"Wilson","year":"2020","journal-title":"Exp Eye Res"},{"issue":"1","key":"bib56","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1006\/exer.1996.0175","article-title":"ZO1 in corneal epithelium: association to the zonula occludens and adherens junctions","volume":"64","author":"Sugrue","year":"1997","journal-title":"Exp Eye Res"},{"key":"bib57","doi-asserted-by":"publisher","first-page":"100852","DOI":"10.1016\/j.eclinm.2021.100852","article-title":"Global economic productivity losses from vision impairment and blindness","volume":"35","author":"Marques","year":"2021","journal-title":"EClinicalMedicine"},{"issue":"3","key":"bib58","doi-asserted-by":"publisher","first-page":"580","DOI":"10.1007\/BF01949227","article-title":"Eine erfolgreiche totale Keratoplastik","volume":"64","author":"Zirm","year":"1906","journal-title":"Graefes Arch Ophthalmol"},{"issue":"1","key":"bib59","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.exer.2006.01.010","article-title":"Corneal integrins and their functions","volume":"83","author":"Stepp","year":"2006","journal-title":"Exp Eye Res"},{"issue":"3","key":"bib60","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1111\/ceo.1996.24.issue-3","article-title":"Allergic reactions to oral, surgical and topical bovine collagen: anaphylactic risk for surgeons","volume":"24","author":"Mullins","year":"1996","journal-title":"Aust N Z J Ophthalmol"},{"issue":"6","key":"bib61","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1016\/S0190-9622(89)70330-3","article-title":"Reactions to a bovine collagen implant","volume":"21","author":"Charriere","year":"1989","journal-title":"J Am Acad Dermatol"},{"issue":"3 Suppl","key":"bib62","doi-asserted-by":"crossref","first-page":"64S","DOI":"10.1097\/01.prs.0000234873.00905.a4","article-title":"ArteFill: a long-lasting injectable wrinkle filler material\u2014summary of the U.S. Food and Drug Administration trials and a progress report on 4- to 5-year outcomes","volume":"118","author":"Cohen","year":"2006","journal-title":"Plast Reconstr Surg"},{"issue":"46","key":"bib63","doi-asserted-by":"publisher","first-page":"45629","DOI":"10.1074\/jbc.M303292200","article-title":"Keratocyte phenotype mediates proteoglycan structure: a role for fibroblasts in corneal fibrosis","volume":"278","author":"Funderburgh","year":"2003","journal-title":"J Biol Chem"},{"key":"bib64","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preteyeres.2015.07.001","article-title":"Corneal structure and transparency","volume":"49","author":"Meek","year":"2015","journal-title":"Prog Retin Eye Res"},{"issue":"3","key":"bib65","doi-asserted-by":"publisher","first-page":"1521","DOI":"10.21873\/invivo.12405","article-title":"Bioluminescence imaging of matrix metalloproteinases-2 and -9 activities in ethanol-injured cornea of mice","volume":"35","author":"Park","year":"2021","journal-title":"In Vivo"},{"issue":"24","key":"bib66","doi-asserted-by":"publisher","first-page":"25326","DOI":"10.1074\/jbc.M403135200","article-title":"Hyaluronan regulates transforming growth factor-\u00df1 receptor compartmentalization","volume":"279","author":"Ito","year":"2004","journal-title":"J Biol Chem"},{"key":"bib67","doi-asserted-by":"publisher","first-page":"108325","DOI":"10.1016\/j.exer.2020.108325","article-title":"TGF\u00df1 and TGF\u00df2 proteins in corneas with and without stromal fibrosis: delayed regeneration of apical epithelial growth factor barrier and the epithelial basement membrane in corneas with stromal fibrosis","volume":"202","author":"de Oliveira","year":"2021","journal-title":"Exp Eye Res"},{"issue":"9","key":"bib68","doi-asserted-by":"publisher","first-page":"3887","DOI":"10.1167\/iovs.07-1348","article-title":"Tissue-engineered recombinant human collagen-based corneal substitutes for implantation: performance of type I versus type III collagen","volume":"49","author":"Merrett","year":"2008","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"2","key":"bib69","doi-asserted-by":"publisher","first-page":"651","DOI":"10.1167\/iovs.10-5224","article-title":"Biosynthetic corneal implants for replacement of pathologic corneal tissue: performance in a controlled rabbit alkali burn model","volume":"52","author":"Hackett","year":"2011","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"61","key":"bib70","doi-asserted-by":"publisher","first-page":"55745","DOI":"10.1039\/C6RA08895C","article-title":"Self-assembled collagen-like-peptide implants as alternatives to human donor corneal transplantation","volume":"6","author":"Islam","year":"2016","journal-title":"RSC Adv"},{"issue":"41","key":"bib71","doi-asserted-by":"publisher","first-page":"1804076","DOI":"10.1002\/adfm.v28.41","article-title":"Cyclodextrin modulated type I collagen self-assembly to engineer biomimetic cornea implants","volume":"28","author":"Majumdar","year":"2018","journal-title":"Adv Funct Mater"},{"issue":"1","key":"bib72","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1038\/s42003-021-02108-y","article-title":"Collagen analogs with phosphorylcholine are inflammation-suppressing scaffolds for corneal regeneration from alkali burns in mini-pigs","volume":"4","author":"Simpson","year":"2021","journal-title":"Commun Biol"},{"key":"bib73","doi-asserted-by":"publisher","first-page":"53","DOI":"10.1016\/j.actbio.2021.10.021","article-title":"Development and characterization of a hydrogel-based adhesive patch for sealing open-globe injuries","volume":"137","author":"Jumelle","year":"2022","journal-title":"Acta Biomater"},{"key":"bib74","doi-asserted-by":"publisher","first-page":"773294","DOI":"10.3389\/fbioe.2021.773294","article-title":"A liquid hydrogel to restore long term corneal integrity after perforating and non-perforating trauma in feline eyes","volume":"9","author":"Juarez","year":"2021","journal-title":"Front Bioeng Biotechnol"},{"issue":"6","key":"bib75","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1167\/tvst.9.6.21","article-title":"Intrastromal injection of hyaluronidase alters the structural and biomechanical properties of the corneal stroma","volume":"9","author":"Kim","year":"2020","journal-title":"Trans Vis Sci Tech"},{"issue":"8","key":"bib76","doi-asserted-by":"publisher","first-page":"5901","DOI":"10.1167\/iovs.12-11575","article-title":"Substratum compliance modulates corneal fibroblast to myofibroblast transformation","volume":"54","author":"Dreier","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib77","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1016\/j.actbio.2017.05.051","article-title":"Tissue and cellular biomechanics during corneal wound injury and repair","volume":"58","author":"Raghunathan","year":"2017","journal-title":"Acta Biomater"},{"issue":"1","key":"bib78","doi-asserted-by":"publisher","first-page":"1496","DOI":"10.1038\/s41467-019-09331-6","article-title":"Assessment of corneal substrate biomechanics and its effect on epithelial stem cell maintenance and differentiation","volume":"10","author":"Gouveia","year":"2019","journal-title":"Nat Commun"},{"key":"bib79","doi-asserted-by":"publisher","first-page":"213","DOI":"10.1016\/j.biomaterials.2017.11.004","article-title":"Stress relaxing hyaluronic acid-collagen hydrogels promote cell spreading, fiber remodeling, and focal adhesion formation in 3D cell culture","volume":"154","author":"Lou","year":"2018","journal-title":"Biomaterials"},{"issue":"3","key":"bib80","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/j.jbiomech.2013.11.019","article-title":"Viscoelastic shear properties of the corneal stroma","volume":"47","author":"Hatami-Marbini","year":"2014","journal-title":"J Biomech"},{"issue":"2","key":"bib81","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.semcdb.2007.09.015","article-title":"Corneal crystallins and the development of cellular transparency","volume":"19","author":"Jester","year":"2008","journal-title":"Semin Cell Dev Biol"},{"issue":"266","key":"bib82","doi-asserted-by":"publisher","first-page":"266ra172","DOI":"10.1126\/scitranslmed.3009644","article-title":"Human limbal biopsy\u2013derived stromal stem cells prevent corneal scarring","volume":"6","author":"Basu","year":"2014","journal-title":"Sci Transl Med"},{"issue":"6","key":"bib83","doi-asserted-by":"publisher","first-page":"500","DOI":"10.1016\/j.jcyt.2021.02.001","article-title":"Effect of mesenchymal stromal cells encapsulated within polyethylene glycol-collagen hydrogels formed in situ on alkali-burned corneas in an ex vivo organ culture model","volume":"23","author":"Na","year":"2021","journal-title":"Cytotherapy"},{"key":"bib45","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/B978-0-323-03599-6.50070-5","article-title":"Corneal topography.","volume-title":"Refractive Surgery.","author":"Roberts","year":"2007","edition":"2nd ed."},{"key":"bib48","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/B978-0-7020-2983-7.00009-7","article-title":"Corneal edema.","volume-title":"Ocular Disease.","author":"Dawson","year":"2010"},{"key":"bib84","author":"Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft (CALEC)"}],"container-title":["Translational Vision Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2783753","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,10,14]],"date-time":"2022-10-14T11:36:00Z","timestamp":1665747360000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2783753"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,14]]},"references-count":84,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2022,10,3]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.11.10.22","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2022,10,14]]}}}