{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T15:18:45Z","timestamp":1769267925050,"version":"3.49.0"},"reference-count":52,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"1","license":[{"start":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T00:00:00Z","timestamp":1672704000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2023,1,3]]},"DOI":"10.1167\/tvst.12.1.3","type":"journal-article","created":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T16:32:39Z","timestamp":1672763559000},"page":"3","source":"Crossref","is-referenced-by-count":9,"title":["Association Between Fatty Acid Intakes and Age-Related Macular Degeneration in a Japanese Population: JPHC-NEXT Eye Study"],"prefix":"10.1167","volume":"12","author":[{"given":"Tomoyo","family":"Yasukawa","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Sasaki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"},{"name":"Tachikawa Hospital, Tokyo, Japan"},{"name":"National Hospital Organization Tokyo Medical Center, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaoru","family":"Motomura","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenya","family":"Yuki","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Toshihide","family":"Kurihara","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yohei","family":"Tomita","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiwako","family":"Mori","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuhiro","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoko","family":"Ozawa","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumasa","family":"Yamagishi","sequence":"additional","affiliation":[{"name":"Department of Public Health Medicine, Faculty of Medicine, and Health Services Research and Development Center, University of Tsukuba, Ibaraki, Japan"},{"name":"Ibaraki Western Medical Center, Ibaraki, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akiko","family":"Hanyuda","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norie","family":"Sawada","sequence":"additional","affiliation":[{"name":"Epidemiology and Prevention Group, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuo","family":"Tsubota","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Keio University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shoichiro","family":"Tsugane","sequence":"additional","affiliation":[{"name":"Epidemiology and Prevention Group, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan"},{"name":"National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyasu","family":"Iso","sequence":"additional","affiliation":[{"name":"Department of Public Health Medicine, Faculty of Medicine, and Health Services Research and Development Center, University of Tsukuba, Ibaraki, Japan"},{"name":"Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine, Osaka, Japan"},{"name":"Institute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27","reference":[{"issue":"9827","key":"bib1","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1016\/S0140-6736(12)60282-7","article-title":"Age-related macular degeneration","volume":"379","author":"Lim","year":"2012","journal-title":"Lancet"},{"issue":"5","key":"bib2","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1016\/j.ophtha.2009.10.007","article-title":"The prevalence of age-related macular degeneration in Asians: a systematic review and meta-analysis","volume":"117","author":"Kawasaki","year":"2010","journal-title":"Ophthalmology"},{"issue":"2","key":"bib3","doi-asserted-by":"publisher","first-page":"e106","DOI":"10.1016\/S2214-109X(13)70145-1","article-title":"Global prevalence of age-related macular degeneration and disease burden projection for 2020 and 2040: a systematic review and meta-analysis","volume":"2","author":"Wong","year":"2014","journal-title":"Lancet Glob Health"},{"issue":"5","key":"bib4","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1001\/archophthalmol.2009.76","article-title":"Dietary fatty acids and the 10-year incidence of age-related macular degeneration: the Blue Mountains Eye Study","volume":"127","author":"Tan","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"3","key":"bib5","doi-asserted-by":"publisher","first-page":"401","DOI":"10.1001\/archopht.118.3.401","article-title":"Dietary fat and fish intake and age-related maculopathy","volume":"118","author":"Smith","year":"2000","journal-title":"Arch Ophthalmol"},{"issue":"5","key":"bib6","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1001\/archopht.125.5.671","article-title":"The relationship of dietary lipid intake and age-related macular degeneration in a case-control study: AREDS Report No. 20","volume":"125","author":"SanGiovanni","year":"2007","journal-title":"Arch Ophthalmol"},{"issue":"6","key":"bib7","doi-asserted-by":"publisher","first-page":"826","DOI":"10.1001\/archopht.126.6.826","article-title":"Dietary omega-3 fatty acid and fish intake in the primary prevention of age-related macular degeneration: a systematic review and meta-analysis","volume":"126","author":"Chong","year":"2008","journal-title":"Arch Ophthalmol"},{"issue":"12","key":"bib8","doi-asserted-by":"publisher","first-page":"1728","DOI":"10.1001\/archopht.121.12.1728","article-title":"Progression of age-related macular degeneration: association with dietary fat, transunsaturated fat, nuts, and fish intake","volume":"121","author":"Seddon","year":"2003","journal-title":"Arch Ophthalmol"},{"issue":"5","key":"bib9","doi-asserted-by":"publisher","first-page":"939","DOI":"10.1016\/j.ophtha.2008.12.025","article-title":"Dietary compound score and risk of age-related macular degeneration in the age-related eye disease study","volume":"116","author":"Chiu","year":"2009","journal-title":"Ophthalmology"},{"issue":"6","key":"bib10","doi-asserted-by":"crossref","first-page":"1601","DOI":"10.3945\/ajcn.2009.27594","article-title":"?-3 Long-chain polyunsaturated fatty acid intake and 12-y incidence of neovascular age-related macular degeneration and central geographic atrophy: AREDS report 30, a prospective cohort study from the Age-Related Eye Disease Study","volume":"90","author":"Sangiovanni","year":"2009","journal-title":"Am J Clin Nutr"},{"issue":"19","key":"bib11","doi-asserted-by":"publisher","first-page":"2005","DOI":"10.1001\/jama.2013.4997","article-title":"Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: the Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial","volume":"309","author":"Age-Related Eye Disease Study 2 Research Group","year":"2013","journal-title":"JAMA"},{"issue":"suppl 2","key":"bib12","doi-asserted-by":"crossref","first-page":"S4","DOI":"10.1017\/S0007114514003912","article-title":"The Mediterranean diet: health, science and society","volume":"113","author":"Gerber","year":"2015","journal-title":"Br J Nutr"},{"issue":"3","key":"bib13","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/j.ophtha.2018.08.006","article-title":"Mediterranean diet and incidence of advanced age-related macular degeneration: the EYE-RISK Consortium","volume":"126","author":"Merle","year":"2019","journal-title":"Ophthalmology"},{"issue":"2","key":"bib14","first-page":"322","article-title":"Fatty acid intakes and food sources in a population of older Australians","volume":"16","author":"Flood","year":"2007","journal-title":"Asia Pac J Clin Nutr"},{"issue":"11","key":"bib15","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1001\/archophthalmol.2009.130","article-title":"Association between dietary fat intake and age-related macular degeneration in the Carotenoids in Age-Related Eye Disease Study (CAREDS): an ancillary study of the Women's Health Initiative","volume":"127","author":"Parekh","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"5","key":"bib16","doi-asserted-by":"publisher","first-page":"674","DOI":"10.1001\/archophthalmol.2009.60","article-title":"Fat consumption and its association with age-related macular degeneration","volume":"127","author":"Chong","year":"2009","journal-title":"Arch Ophthalmol"},{"issue":"2","key":"bib17","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1167\/iovs.61.2.20","article-title":"Higher intake of polyunsaturated fatty acid and monounsaturated fatty acid is inversely associated with AMD","volume":"61","author":"Roh","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"7","key":"bib18","doi-asserted-by":"publisher","first-page":"e0160240","DOI":"10.1371\/journal.pone.0160240","article-title":"Olive oil consumption and age-related macular degeneration: the Alienor study","volume":"11","author":"Cougnard-Gr\u00e9goire","year":"2016","journal-title":"PLoS One"},{"issue":"6","key":"bib19","doi-asserted-by":"publisher","first-page":"743","DOI":"10.1001\/archopht.1995.01100060069034","article-title":"Dietary fat and age-related maculopathy","volume":"113","author":"Mares-Perlman","year":"1995","journal-title":"Arch Ophthalmol"},{"issue":"2","key":"bib20","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1093\/ajcn\/73.2.209","article-title":"Prospective study of dietary fat and the risk of age-related macular degeneration","volume":"73","author":"Cho","year":"2001","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"bib21","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/j.ajo.2007.03.047","article-title":"Clinical characteristics of exudative age-related macular degeneration in Japanese patients","volume":"144","author":"Maruko","year":"2007","journal-title":"Am J Ophthalmol"},{"issue":"10","key":"bib22","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1016\/j.ophtha.2020.04.019","article-title":"Prevalence and pattern of geographic atrophy in Asia: the Asian Eye Epidemiology Consortium","volume":"127","author":"Rim","year":"2020","journal-title":"Ophthalmology"},{"issue":"1","key":"bib23","doi-asserted-by":"publisher","first-page":"139","DOI":"10.1007\/s00439-006-0187-0","article-title":"No association between complement factor H gene polymorphism and exudative age-related macular degeneration in Japanese","volume":"120","author":"Gotoh","year":"2006","journal-title":"Hum Genet"},{"issue":"9","key":"bib24","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1038\/sj.jhh.1001605","article-title":"Nutrient intakes of middle-aged men and women in China, Japan, United Kingdom, and United States in the late 1990s: the INTERMAP study","volume":"17","author":"Zhou","year":"2003","journal-title":"J Hum Hypertens"},{"issue":"3","key":"bib25","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1167\/iovs.61.3.23","article-title":"Dietary saturated fatty acid intake and early age-related macular degeneration in a Japanese population","volume":"61","author":"Sasaki","year":"2020","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib26","doi-asserted-by":"publisher","first-page":"46","DOI":"10.2188\/jea.JE20180182","article-title":"The Japan Public Health Center-based Prospective Study for the Next Generation (JPHC-NEXT): study design and participants","volume":"30","author":"Sawada","year":"2020","journal-title":"J Epidemiol"},{"issue":"11","key":"bib27","doi-asserted-by":"crossref","first-page":"1983","DOI":"10.1097\/00004872-200311000-00002","article-title":"2003 World Health Organization (WHO)\/International Society of Hypertension (ISH) statement on management of hypertension","volume":"21","author":"Whitworth","year":"2003","journal-title":"J Hypertens"},{"issue":"5","key":"bib28","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1111\/j.2040-1124.2010.00074.x","article-title":"Report of the committee on the classification and diagnostic criteria of diabetes mellitus","volume":"1","author":"Committee of the Japan Diabetes Society on the Diagnostic Criteria of Diabetes Mellitus","year":"2010","journal-title":"J Diabetes Investig"},{"issue":"4","key":"bib29","doi-asserted-by":"publisher","first-page":"155","DOI":"10.5551\/jat.E537","article-title":"Diagnostic criteria for dyslipidemia. Executive summary of Japan Atherosclerosis Society (JAS) guideline for diagnosis and prevention of atherosclerotic cardiovascular diseases for Japanese","volume":"14","author":"Teramoto","year":"2007","journal-title":"J Atheroscler Thromb"},{"issue":"5","key":"bib30","first-page":"668","article-title":"The Age-Related Eye Disease Study system for classifying age-related macular degeneration from stereoscopic color fundus photographs: the Age-Related Eye Disease Study Report Number 6","volume":"13","author":"Age-Related Eye Disease Study Research Group","year":"2001","journal-title":"Am J Ophthalmol"},{"issue":"8","key":"bib31","doi-asserted-by":"publisher","first-page":"420","DOI":"10.2188\/jea.JE20150064","article-title":"Validity of short and long self-administered food frequency questionnaires in ranking dietary intake in middle-aged and elderly Japanese in the Japan Public Health Center-Based Prospective Study for the Next Generation (JPHC-NEXT) protocol area","volume":"26","author":"Yokoyama","year":"2016","journal-title":"J Epidemiol"},{"issue":"4","key":"bib33","doi-asserted-by":"publisher","first-page":"1220S","DOI":"10.1093\/ajcn\/65.4.1220S","article-title":"Adjustment for total energy intake in epidemiologic studies","volume":"65","author":"Willett","year":"1997","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"bib34","doi-asserted-by":"publisher","first-page":"32","DOI":"10.1093\/aje\/kwf166","article-title":"Fat and protein intakes and risk of intraparenchymal hemorrhage among middle-aged Japanese","volume":"157","author":"Iso","year":"2003","journal-title":"Am J Epidemiol"},{"issue":"16","key":"bib37","doi-asserted-by":"publisher","first-page":"1225","DOI":"10.1093\/eurheartj\/eht043","article-title":"Dietary intake of saturated fatty acids and incident stroke and coronary heart disease in Japanese communities: the JPHC Study","volume":"34","author":"Yamagishi","year":"2013","journal-title":"Eur Heart J"},{"issue":"7","key":"bib38","doi-asserted-by":"publisher","first-page":"954","DOI":"10.1161\/01.STR.24.7.954","article-title":"Associations of serum total cholesterol, different types of stroke, and stenosis distribution of cerebral arteries. The Akita Pathology Study","volume":"24","author":"Konishi","year":"1993","journal-title":"Stroke"},{"issue":"2","key":"bib39","doi-asserted-by":"publisher","first-page":"83","DOI":"10.5551\/jat.6866","article-title":"Lifestyle and cardiovascular disease in Japan","volume":"18","author":"Iso","year":"2011","journal-title":"J Atheroscler Thromb"},{"issue":"8","key":"bib40","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1016\/j.molmed.2016.06.009","article-title":"A Revised hemodynamic theory of age-related macular degeneration","volume":"22","author":"Gelfand","year":"2016","journal-title":"Trends Mol Med"},{"issue":"6","key":"bib41","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1007\/s11357-019-00138-3","article-title":"Microvascular contributions to age-related macular degeneration (AMD): from mechanisms of choriocapillaris aging to novel interventions","volume":"41","author":"Lipecz","year":"2019","journal-title":"Geroscience"},{"issue":"1","key":"bib42","doi-asserted-by":"publisher","first-page":"330","DOI":"10.3390\/ijms22010330","article-title":"Monounsaturated fatty acids in obesity-related inflammation","volume":"22","author":"Ravaut","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"4","key":"bib43","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1111\/nure.2004.62.issue-4","article-title":"Monounsaturated fatty acid intake by children and adults: temporal trends and demographic differences","volume":"62","author":"Nicklas","year":"2004","journal-title":"Nutr Rev"},{"issue":"2","key":"bib44","doi-asserted-by":"publisher","first-page":"78","DOI":"10.2188\/jea.9.78","article-title":"Foods contributing to absolute intake and variance in intake of fat, fatty acids and cholesterol in middle-aged Japanese","volume":"9","author":"Tokudome","year":"1999","journal-title":"J Epidemiol"},{"issue":"6","key":"bib45","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1210\/mend.11.6.0007","article-title":"Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay","volume":"11","author":"Krey","year":"1997","journal-title":"Mol Endocrinol"},{"issue":"3","key":"bib46","doi-asserted-by":"publisher","first-page":"397","DOI":"10.1016\/S1097-2765(00)80467-0","article-title":"Molecular recognition of fatty acids by peroxisome proliferator-activated receptors","volume":"3","author":"Xu","year":"1999","journal-title":"Mol Cell"},{"issue":"45","key":"bib47","doi-asserted-by":"publisher","first-page":"32048","DOI":"10.1074\/jbc.274.45.32048","article-title":"Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1","volume":"274","author":"Delerive","year":"1999","journal-title":"J Biol Chem"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"20723","DOI":"10.1038\/srep20723","article-title":"Dietary n-3 fatty acid, a-tocopherol, zinc, vitamin D, vitamin C, and \u00df-carotene are associated with age-related macular degeneration in Japan","volume":"6","author":"Aoki","year":"2016","journal-title":"Sci Rep"},{"issue":"2","key":"bib51","doi-asserted-by":"publisher","first-page":"254","DOI":"10.1001\/archopthalmol.2011.1368","article-title":"Use of micronutrient supplement for preventing advanced age-related macular degeneration in Japan","volume":"130","author":"Sasaki","year":"2012","journal-title":"Arch Ophthalmol"},{"issue":"6","key":"bib52","doi-asserted-by":"publisher","first-page":"1032","DOI":"10.1016\/j.ophtha.2007.08.003","article-title":"Vitamin usage patterns in the prevention of advanced age-related macular degeneration","volume":"115","author":"Charkoudian","year":"2008","journal-title":"Ophthalmology"},{"key":"bib32","volume-title":"Standard Tables of Food Composition in Japan","author":"Science and Technology Agency","year":"2000","edition":"5th rev ed"},{"key":"bib35","volume-title":"Nutrient Intakes from Food and Beverages: Mean Amounts Consumed per Individual, by Gender and Age, What We Eat in America, NHANES 2017-2018","author":"US Department of Agriculture, Agricultural Research Service","year":"2020"},{"key":"bib36","article-title":"The National Health and Nutrition Survey","author":"Ministry of Health, Labour and Welfare, Japan","year":"2018"},{"key":"bib49","article-title":"Council for Responsible Nutrition Consumer Survey on Dietary Supplements","year":"2019"},{"key":"bib50","article-title":"The National Health and Nutrition Survey","author":"Ministry of Health, Labour and Welfare, Japan","year":"2019"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2785252","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,3]],"date-time":"2023-01-03T16:32:50Z","timestamp":1672763570000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2785252"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,1,3]]},"references-count":52,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,1,3]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.12.1.3","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2023,1,3]]}}}