{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T08:03:37Z","timestamp":1793261017889,"version":"4.5.0"},"reference-count":37,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"6","license":[{"start":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T00:00:00Z","timestamp":1687392000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2023,6,22]]},"DOI":"10.1167\/tvst.12.6.14","type":"journal-article","created":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T22:02:19Z","timestamp":1687557739000},"page":"14","source":"Crossref","is-referenced-by-count":6,"title":["Description of a Nonhuman Primate Model of Retinal Ischemia\/Reperfusion Injury"],"prefix":"10.1167","volume":"12","author":[{"given":"Li","family":"Gong","sequence":"first","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louis R.","family":"Pasquale","sequence":"additional","affiliation":[{"name":"Eye and Vision Research Institute at New York Eye and Ear Infirmary of Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janey L.","family":"Wiggs","sequence":"additional","affiliation":[{"name":"Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingzhen","family":"Pan","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenyan","family":"Yang","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingling","family":"Wu","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zirui","family":"Zeng","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zunyuan","family":"Yang","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yubo","family":"Shen","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Feng","family":"Chen","sequence":"additional","affiliation":[{"name":"Schepens Eye Research Institute of Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen","family":"Zeng","sequence":"additional","affiliation":[{"name":"PriMed Non-human Primate Research Center of Sichuan PriMed Shines Bio-tech Co., Ltd., Ya'an, Sichuan Province, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"444","DOI":"10.3389\/fimmu.2016.00444","article-title":"Cellular stress response and immune signaling in retinal ischemia-reperfusion injury","volume":"7","author":"Minhas","year":"2016","journal-title":"Front Immunol"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1016\/j.oret.2021.05.004","article-title":"Age, gender, and laterality of retinal vascular occlusion: a retrospective study from the IRIS Registry","volume":"6","author":"Li","year":"2022","journal-title":"Ophthalmol Retina"},{"key":"bib3","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1016\/j.ajpath.2020.04.011","article-title":"CD4+ T-cell responses mediate progressive neurodegeneration in experimental ischemic retinopathy","volume":"190","author":"Vu","year":"2020","journal-title":"Am J Pathol"},{"issue":"4","key":"bib4","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1167\/tvst.8.4.23","article-title":"Animal models used to simulate retinal artery occlusion: a comprehensive review","volume":"8","author":"Vestergaard","year":"2019","journal-title":"Transl Vis Sci Technol"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"3136","DOI":"10.1167\/iovs.18-24261","article-title":"A novel tree shrew (Tupaia belangeri) model of glaucoma","volume":"59","author":"Samuels","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"2568","DOI":"10.1161\/STROKEAHA.119.028809","article-title":"Novel acute retinal artery ischemia and reperfusion model in nonhuman primates","volume":"51","author":"Gao","year":"2020","journal-title":"Stroke"},{"issue":"15","key":"bib7","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1167\/iovs.62.15.18","article-title":"Analysis of microvasculature in nonhuman primate macula with acute elevated intraocular pressure using optical coherence tomography angiography","volume":"62","author":"Choi","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib8","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1167\/tvst.10.9.20","article-title":"Development of primary open angle glaucoma-like features in a rhesus macaque colony from southern China","volume":"10","author":"Pasquale","year":"2021","journal-title":"Transl Vis Sci Technol"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s10633-014-9473-7","article-title":"ISCEV Standard for full-field clinical electroretinography (2015 update)","volume":"130","author":"McCulloch","year":"2015","journal-title":"Doc Ophthalmol"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1159\/000111185","article-title":"GFAP gene expression during development of astrocyte","volume":"19","author":"Baba","year":"1997","journal-title":"Dev Neurosci"},{"issue":"7 Pt 1","key":"bib11","doi-asserted-by":"crossref","first-page":"4762","DOI":"10.1523\/JNEUROSCI.15-07-04762.1995","article-title":"The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons","volume":"15","author":"Xiang","year":"1995","journal-title":"J Neurosci"},{"issue":"1","key":"bib12","doi-asserted-by":"publisher","first-page":"16505","DOI":"10.1038\/s41598-020-73585-0","article-title":"Differential reperfusion patterns in retinal vascular plexuses following increase in intraocular pressure an OCT angiography study","volume":"10","author":"Cheung","year":"2020","journal-title":"Sci Rep"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"21","DOI":"10.1186\/1750-1326-8-21","article-title":"Progressive morphological changes and impaired retinal function associated with temporal regulation of gene expression after retinal ischemia\/reperfusion injury in mice","volume":"8","author":"Kim","year":"2013","journal-title":"Mol Neurodegener"},{"issue":"2","key":"bib14","doi-asserted-by":"publisher","first-page":"527","DOI":"10.1167\/iovs.15-17880","article-title":"Peripapillary Retinal Nerve Fiber Layer Swelling Predicts Peripapillary Atrophy in a Primate Model of Nonarteritic Anterior Ischemic Optic Neuropathy","volume":"57","author":"Johnson","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3-4","key":"bib15","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1023\/B:MEBR.0000043966.46964.e6","article-title":"Pathophysiology of stroke: lessons from animal models","volume":"19","author":"Mergenthaler","year":"2004","journal-title":"Metab Brain Dis"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"1185","DOI":"10.1161\/01.CIR.95.5.1185","article-title":"Pathophysiology of transient myocardial ischemia in acute coronary syndromes. Characterization by continuous ST-segment monitoring","volume":"95","author":"Patel","year":"1997","journal-title":"Circulation"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.preteyeres.2003.12.001","article-title":"Retinal ischemia: mechanisms of damage and potential therapeutic strategies","volume":"23","author":"Osborne","year":"2004","journal-title":"Prog Retin Eye Res"},{"issue":"4 Pt 1","key":"bib18","first-page":"OP694","article-title":"Patterns of ischemia in diabetic retinopathy","volume":"81","author":"Bresnick","year":"1976","journal-title":"Trans Sect Ophthalmol Am Acad Ophthalmol Otolaryngol"},{"issue":"Suppl. 2","key":"bib19","doi-asserted-by":"crossref","first-page":"S162","DOI":"10.1016\/j.survophthal.2007.08.012","article-title":"What is the present pathogenetic concept of glaucomatous optic neuropathy","volume":"52","author":"Flammer","year":"2007","journal-title":"Surv Ophthalmol"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"361","DOI":"10.1167\/iovs.06-0510","article-title":"Retinal ischemia and reperfusion causes capillary degeneration: similarities to diabetes","volume":"48","author":"Zheng","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"bib21","doi-asserted-by":"publisher","first-page":"2777","DOI":"10.1167\/iovs.13-13372","article-title":"Loss of inner retinal neurons after retinal ischemia in rats","volume":"55","author":"Schmid","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"174","DOI":"10.3389\/fncel.2019.00174","article-title":"From Ganglion Cell to Photoreceptor Layer: timeline of deterioration in a rat ischemia\/reperfusion model","volume":"13","author":"Palmhof","year":"2019","journal-title":"Front Cell Neurosci"},{"key":"bib23","first-page":"00232","article-title":"Experimental animal models for retinal and choroidal diseases","volume":"7","author":"Turgut","year":"2017","journal-title":"Adv Ophthalmol Vis Syst"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.exer.2015.06.005","article-title":"The non-human primate experimental glaucoma model","volume":"141","author":"Burgoyne","year":"2015","journal-title":"Exp Eye Res"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"4719","DOI":"10.1167\/iovs.08-3289","article-title":"The effect of acute intraocular pressure elevation on peripapillary retinal thickness, retinal nerve fiber layer thickness, and retardance","volume":"50","author":"Fortune","year":"2009","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"bib26","doi-asserted-by":"publisher","first-page":"e680","DOI":"10.1111\/aos.v98.6","article-title":"Retinal oedema in central retinal artery occlusion develops as a function of time","volume":"98","author":"Ochakovski","year":"2020","journal-title":"Acta Ophthalmol"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1007\/s12028-020-00959-7","article-title":"Guidelines for the acute treatment of cerebral edema in neurocritical care patients","volume":"32","author":"Cook","year":"2020","journal-title":"Neurocrit Care"},{"issue":"9","key":"bib28","doi-asserted-by":"publisher","first-page":"e183","DOI":"10.1161\/STROKEAHA.120.030256","article-title":"Dynamic regional brain atrophy rates in the first year after ischemic stroke","volume":"51","author":"Brodtmann","year":"2020","journal-title":"Stroke"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"567","DOI":"10.1001\/archopht.123.4.567","article-title":"Optical coherence tomography of optic disc swelling in acute primary angle-closure glaucoma","volume":"123","author":"Yip","year":"2005","journal-title":"Arch Ophthalmol"},{"issue":"8","key":"bib30","doi-asserted-by":"publisher","first-page":"e23194","DOI":"10.1371\/journal.pone.0023194","article-title":"Curcumin inhibits neuronal and vascular degeneration in retina after ischemia and reperfusion injury","volume":"6","author":"Wang","year":"2011","journal-title":"PLoS One"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"723","DOI":"10.1016\/S0014-4835(03)00214-8","article-title":"Central retinal artery occlusion. Retinal survival time","volume":"78","author":"Hayreh","year":"2004","journal-title":"Exp Eye Res"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1167\/iovs.03-0285","article-title":"Ischemia-induced changes of AMPA-type glutamate receptor subunit expression pattern in the rat retina: a real-time quantitative PCR study","volume":"45","author":"Dijk","year":"2004","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib33","doi-asserted-by":"publisher","first-page":"25","DOI":"10.5115\/acb.2011.44.1.25","article-title":"Immunochemical changes of calbindin, calretinin and SMI32 in ischemic retinas induced by increase of intraocular pressure and by middle cerebral artery occlusion","volume":"44","author":"Lee","year":"2011","journal-title":"Anat Cell Biol"},{"issue":"1","key":"bib34","doi-asserted-by":"publisher","first-page":"e16380","DOI":"10.1371\/journal.pone.0016380","article-title":"Lycium barbarum polysaccharides reduce neuronal damage, blood-retinal barrier disruption and oxidative stress in retinal ischemia\/reperfusion injury","volume":"6","author":"Li","year":"2011","journal-title":"PLoS One"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1093\/bmb\/ldh025","article-title":"Vascular ischaemia and reperfusion injury","volume":"70","author":"Eltzschig","year":"2004","journal-title":"Br Med Bull"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"429","DOI":"10.1002\/(ISSN)1096-9896","article-title":"Blood-retinal barrier disruption and ultrastructural changes in the hypoxic retina in adult rats: the beneficial effect of melatonin administration","volume":"212","author":"Kaur","year":"2007","journal-title":"J Pathol"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"601","DOI":"10.2147\/OPTH.S272126","article-title":"Intra-arterial tissue plasminogen activator for central retinal artery occlusion","volume":"15","author":"Sobol","year":"2021","journal-title":"Clin Ophthalmol"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2785720","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,23]],"date-time":"2023-06-23T22:02:25Z","timestamp":1687557745000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2785720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,22]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.12.6.14","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2023,6,22]]}}}