{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T21:21:19Z","timestamp":1792876879133,"version":"4.5.0"},"reference-count":37,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"10","license":[{"start":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T00:00:00Z","timestamp":1728604800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2024,10,11]]},"DOI":"10.1167\/tvst.13.10.21","type":"journal-article","created":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T14:30:57Z","timestamp":1728657057000},"page":"21","source":"Crossref","is-referenced-by-count":21,"title":["Artificial Intelligence\u2013Enhanced OCT Biomarkers Analysis in Macula-off Rhegmatogenous Retinal Detachment Patients"],"prefix":"10.1167","volume":"13","author":[{"given":"Lorenzo","family":"Ferro Desideri","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"},{"name":"Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tamara","family":"Danilovska","sequence":"additional","affiliation":[{"name":"ARTORG Research Center Biomedical Engineering Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Enrico","family":"Bernardi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dmitri","family":"Artemiev","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karin","family":"Paschon","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel","family":"Hayoz","sequence":"additional","affiliation":[{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alain","family":"Jungo","sequence":"additional","affiliation":[{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raphael","family":"Sznitman","sequence":"additional","affiliation":[{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin S.","family":"Zinkernagel","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"},{"name":"Bern Photographic Reading Center, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodrigo","family":"Anguita","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland"},{"name":"Department for BioMedical Research, University of Bern, Bern, Switzerland"},{"name":"Moorfields Eye Hospital NHS Foundation Trust, London, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"10","key":"bib1","doi-asserted-by":"publisher","first-page":"1297","DOI":"10.1136\/bjophthalmol-2013-303637","article-title":"Macular displacement following rhegmatogenous retinal detachment repair","volume":"97","author":"Lee","year":"2013","journal-title":"Br J Ophthalmol"},{"issue":"6","key":"bib2","doi-asserted-by":"publisher","first-page":"652","DOI":"10.1001\/jamaophthalmol.2020.1046","article-title":"Retinal displacement following pneumatic retinopexy vs pars plana vitrectomy for rhegmatogenous retinal detachment","volume":"138","author":"Brosh","year":"2020","journal-title":"JAMA Ophthalmol"},{"issue":"10","key":"bib3","doi-asserted-by":"publisher","first-page":"1917","DOI":"10.1097\/IAE.0000000000000296","article-title":"Impact of duration of macula-off retinal detachment on visual outcome: a systematic review and meta-analysis of literature","volume":"34","author":"van Bussel","year":"2014","journal-title":"Retina"},{"issue":"3","key":"bib4","first-page":"525","article-title":"Impact of duration of macula off rhegmatogenous retinal detachment on visual outcome","volume":"30","author":"Khanzada","year":"2014","journal-title":"Pak J Med Sci"},{"issue":"5","key":"bib5","doi-asserted-by":"publisher","first-page":"597","DOI":"10.1111\/j.1600-0420.2006.00676.x","article-title":"Macular recovery after retinal detachment","volume":"84","author":"Abouzeid","year":"2006","journal-title":"Acta Ophthalmol Scand"},{"issue":"12","key":"bib6","doi-asserted-by":"publisher","first-page":"1779","DOI":"10.1001\/archopht.124.12.1779","article-title":"Charteris DG. Glial and neural response in short-term human retinal detachment","volume":"124","author":"Wickham","year":"2006","journal-title":"Arch Ophthalmol"},{"issue":"2","key":"bib7","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1385\/MN:28:2:159","article-title":"Experimental retinal reattachment: a new perspective","volume":"28","author":"Lewis","year":"2003","journal-title":"Mol Neurobiol"},{"issue":"11","key":"bib8","doi-asserted-by":"publisher","first-page":"1583","DOI":"10.1136\/bjo-2022-321845","article-title":"Visual loss in surgical retinal disease: retinal imaging and photoreceptor cell counts","volume":"107","author":"Anguita","year":"2023","journal-title":"Br J Ophthalmol"},{"issue":"3","key":"bib9","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1167\/iovs.15-18403","article-title":"Association between photoreceptor regeneration and visual acuity following surgery for rhegmatogenous retinal detachment","volume":"57","author":"Kobayashi","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib10","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1016\/j.oret.2018.10.006","article-title":"Intraoperative OCT features and postoperative ellipsoid mapping in primary macula-involving retinal detachments from the PIONEER Study","volume":"3","author":"Abraham","year":"2019","journal-title":"Ophthalmol Retina"},{"issue":"1","key":"bib11","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1097\/IAE.0b013e3182180114","article-title":"Correlation between spectral-domain optical coherence tomography findings and visual outcome after primary rhegmatogenous retinal detachment repair","volume":"32","author":"Gharbiya","year":"2012","journal-title":"Retina"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"212","DOI":"10.1016\/j.ajo.2021.10.012","article-title":"Longitudinal assessment of ellipsoid zone recovery using en face optical coherence tomography after retinal detachment repair","volume":"236","author":"Figueiredo","year":"2022","journal-title":"Am J Ophthalmol"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preteyeres.2018.07.004","article-title":"Bogunovic H. Artificial intelligence in retina","volume":"67","author":"Schmidt-Erfurth","year":"2018","journal-title":"Prog Retin Eye Res"},{"issue":"7","key":"bib14","doi-asserted-by":"publisher","first-page":"740","DOI":"10.1001\/jamaophthalmol.2020.1376","article-title":"Characterization of drusen and hyperreflective foci as biomarkers for disease progression in age-related macular degeneration using artificial intelligence in optical coherence tomography","volume":"138","author":"Waldstein","year":"2020","journal-title":"JAMA Ophthalmol"},{"issue":"5","key":"bib15","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1097\/ICU.0000000000000782","article-title":"Artificial intelligence-based predictions in neovascular age-related macular degeneration","volume":"32","author":"Ferrara","year":"2021","journal-title":"Curr Opin Ophthalmol"},{"issue":"2","key":"bib16","first-page":"316","article-title":"Baseline spectral domain optical coherence tomographic retinal layer features identified by artificial intelligence predict the course of central serous chorioretinopathy","volume":"44","author":"Desideri","year":"2024","journal-title":"Retina"},{"issue":"3","key":"bib17","doi-asserted-by":"publisher","first-page":"715","DOI":"10.1007\/s00417-022-05884-3","article-title":"Artificial intelligence using deep learning to predict the anatomical outcome of rhegmatogenous retinal detachment surgery: a pilot study","volume":"261","author":"Fung","year":"2023","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"issue":"1","key":"bib18","doi-asserted-by":"publisher","first-page":"13605","DOI":"10.1038\/s41598-019-49740-7","article-title":"Expert-level automated biomarker identification in optical coherence tomography scans","volume":"9","author":"Kurmann","year":"2019","journal-title":"Sci Rep"},{"issue":"3","key":"bib19","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1016\/j.ophtha.2008.10.001","article-title":"Foveal microstructure and visual acuity after retinal detachment repair: imaging analysis by Fourier-domain optical coherence tomography","volume":"116","author":"Wakabayashi","year":"2009","journal-title":"Ophthalmology"},{"issue":"2","key":"bib20","doi-asserted-by":"publisher","first-page":"284","DOI":"10.1016\/j.ajo.2009.08.025","article-title":"Restoration of photoreceptor outer segment after vitrectomy for retinal detachment","volume":"149","author":"Shimoda","year":"2010","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib21","doi-asserted-by":"publisher","first-page":"137","DOI":"10.1097\/IAE.0000000000001512","article-title":"Factors associated with visual outcome after macula-off rhegmatogenous retinal detachment surgery","volume":"38","author":"Park","year":"2018","journal-title":"Retina"},{"issue":"1","key":"bib22","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1016\/j.ajo.2011.06.010","article-title":"Creuzot-Garcher C. Anatomical and functional macular changes after rhegmatogenous retinal detachment with macula off","volume":"153","author":"Delolme","year":"2012","journal-title":"Am J Ophthalmol"},{"issue":"10","key":"bib23","doi-asserted-by":"publisher","first-page":"6575","DOI":"10.1167\/iovs.14-14412","article-title":"Retinal layer measurements after successful macula-off retinal detachment repair using optical coherence tomography","volume":"55","author":"Menke","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"bib24","doi-asserted-by":"publisher","first-page":"375","DOI":"10.1038\/sj.eye.6700202","article-title":"Animal models of retinal detachment and reattachment: identifying cellular events that may affect visual recovery","volume":"16","author":"Lewis","year":"2002","journal-title":"Eye (Lond)"},{"issue":"1","key":"bib25","first-page":"175","article-title":"Recovery of photoreceptor outer segment length and analysis of membrane assembly rates in regenerating primate photoreceptor outer segments","volume":"34","author":"Guer\u00edn","year":"1993","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"103763","DOI":"10.1016\/j.pdpdt.2023.103763","article-title":"Changes of optical coherence tomographic hyperreflective foci in rhegmatogenous retinal detachment patients after successful surgery","volume":"44","author":"Wu","year":"2023","journal-title":"Photodiagnosis Photodyn Ther"},{"issue":"12","key":"bib27","doi-asserted-by":"publisher","first-page":"1087","DOI":"10.1016\/j.oret.2023.07.016","article-title":"Outer retinal hyperreflective dots: a potential imaging biomarker in rhegmatogenous retinal detachment","volume":"7","author":"Jhaveri","year":"2023","journal-title":"Ophthalmol Retina"},{"issue":"4","key":"bib28","doi-asserted-by":"publisher","first-page":"710","DOI":"10.1016\/j.ajo.2011.08.041","article-title":"Association between hyperreflective foci in the outer retina, status of photoreceptor layer, and visual acuity in diabetic macular edema","volume":"153","author":"Uji","year":"2012","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib29","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1097\/IAE.0b013e318217ffc7","article-title":"Characteristics of optical coherence tomographic hyperreflective foci in retinal vein occlusion","volume":"32","author":"Ogino","year":"2012","journal-title":"Retina"},{"issue":"1","key":"bib30","doi-asserted-by":"publisher","first-page":"20","DOI":"10.1167\/iovs.64.1.20","article-title":"Hyper-reflective foci in intermediate age-related macular degeneration: spatial abundance and impact on retinal morphology","volume":"64","author":"Sassmannshausen","year":"2023","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"10","key":"bib31","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1167\/iovs.62.10.34","article-title":"Hyperreflective foci, optical coherence tomography progression indicators in age-related macular degeneration, include transdifferentiated retinal pigment epithelium","volume":"62","author":"Cao","year":"2021","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"6","key":"bib32","first-page":"BIO211","article-title":"Activated retinal pigment epithelium, an optical coherence tomography biomarker for progression in age-related macular degeneration","volume":"58","author":"Curcio","year":"2017","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"27","key":"bib33","doi-asserted-by":"publisher","first-page":"E6264","DOI":"10.1073\/pnas.1719601115","article-title":"Microglia inhibit photoreceptor cell death and regulate immune cell infiltration in response to retinal detachment","volume":"115","author":"Okunuki","year":"2018","journal-title":"Proc Natl Acad Sci USA"},{"issue":"7","key":"bib34","first-page":"906","article-title":"Retinal detachment in the cat: the pigment epithelial-photoreceptor interface","volume":"24","author":"Anderson","year":"1983","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"9","key":"bib35","doi-asserted-by":"publisher","first-page":"564","DOI":"10.1136\/bjo.61.9.564","article-title":"Observations on the retinal pigment epithelium and retinal macrophages in experimental retinal detachment","volume":"61","author":"Johnson","year":"1977","journal-title":"Br J Ophthalmol"},{"issue":"suppl 1","key":"bib36","first-page":"S23","article-title":"Clinical significance of macula-off rhegmatogenous retinal detachment preoperative features on optical coherence tomography","volume":"52","author":"Felfeli","year":"2021","journal-title":"Ophthalmic Surg Lasers Imaging Retina"},{"issue":"1","key":"bib37","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1186\/s12886-019-1120-3","article-title":"Functional and morphological results of treatment of macula-on and macula-off rhegmatogenous retinal detachment with pars plana vitrectomy and sulfur hexafluoride gas tamponade","volume":"19","author":"Borowicz","year":"2019","journal-title":"BMC Ophthalmol"}],"container-title":["Translational Vision Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2802124","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,11]],"date-time":"2024-10-11T14:31:00Z","timestamp":1728657060000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2802124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,11]]},"references-count":37,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,10,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.13.10.21","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10,11]]}}}