{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T15:46:21Z","timestamp":1790178381164,"version":"4.1.0"},"reference-count":56,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"2","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2024,2,20]]},"DOI":"10.1167\/tvst.13.2.15","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T16:31:01Z","timestamp":1708446661000},"page":"15","source":"Crossref","is-referenced-by-count":10,"title":["In Vivo Evaluation of Corneal Biomechanics Following Cross-Linking Surgeries Using Optical Coherence Elastography in a Rabbit Model of Keratoconus"],"prefix":"10.1167","volume":"13","author":[{"given":"Yanzhi","family":"Zhao","sequence":"first","affiliation":[{"name":"Eye Center, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yirui","family":"Zhu","sequence":"additional","affiliation":[{"name":"School of Physics, University of Nanjing, Nanjing, Jiangsu, China"},{"name":"School of Testing and Opto-electronic Engineering, Nanchang Hangkong University, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yange","family":"Yan","sequence":"additional","affiliation":[{"name":"Yujiang District People's Hospital, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Yang","sequence":"additional","affiliation":[{"name":"Eye Center, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingchao","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Nanchang First Hospital, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongan","family":"Lu","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Nanchang First Hospital, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingjie","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Nanchang First Hospital, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofu","family":"Huang","sequence":"additional","affiliation":[{"name":"Eye Center, Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"S350","DOI":"10.1097\/ICL.0000000000000492","article-title":"Vision-related quality of life in Iranian patients with keratoconus: national eye institute vision function questionnaire-25","volume":"44","author":"Mahdaviazad","year":"2018","journal-title":"Eye Contact Lens"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"1582","DOI":"10.1016\/j.jcrs.2017.08.024","article-title":"Vision-related quality of life and dependency in French keratoconus patients: impact study","volume":"43","author":"Saunier","year":"2017","journal-title":"J Cataract Refract Surg"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1016\/0039-6257(84)90094-8","article-title":"Keratoconus and related noninflammatory corneal thinning disorders","volume":"28","author":"Krachmer","year":"1984","journal-title":"Surv Ophthalmol"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","article-title":"Keratoconus","volume":"42","author":"Rabinowitz","year":"1998","journal-title":"Surv Ophthalmol"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"2159","DOI":"10.1016\/j.ophtha.2008.08.004","article-title":"Keratoconus diagnosis with optical coherence tomography pachymetry mapping","volume":"115","author":"Li","year":"2008","journal-title":"Ophthalmology"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/j.clae.2004.12.001","article-title":"Corneal wavefront aberration measurements to detect keratoconus patients","volume":"28","author":"Gobbe","year":"2005","journal-title":"Contact Lens Anterior Eye"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"211","DOI":"10.1111\/ceo.2004.32.issue-2","article-title":"Morphological changes in keratoconus: pathology or pathogenesis","volume":"32","author":"Sherwin","year":"2004","journal-title":"Clin Exp Ophthalmol"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"1948","DOI":"10.1167\/iovs.04-1253","article-title":"Changes in collagen orientation and distribution in keratoconus corneas","volume":"46","author":"Meek","year":"2005","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"44","DOI":"10.1097\/00055735-199508000-00009","article-title":"Corneal dystrophies and keratoconus","volume":"6","author":"Klintworth","year":"1995","journal-title":"Curr Opin Ophthalmol"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"e649","DOI":"10.1111\/aos.2017.95.issue-7","article-title":"Iontophoretic collagen cross-linking versus epithelium-off collagen cross-linking for early stage of progressive keratoconus\u20133\u00a0years follow-up study","volume":"95","author":"Cantemir","year":"2017","journal-title":"Acta Ophthalmol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"e52860","DOI":"10.1371\/journal.pone.0052860","article-title":"The effect of riboflavin\/UVA collagen cross-linking therapy on the structure and hydrodynamic behaviour of the ungulate and rabbit corneal stroma","volume":"8","author":"Hayes","year":"2013","journal-title":"PLoS One"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"620","DOI":"10.1016\/S0002-9394(02)02220-1","article-title":"Riboflavin\/ultraviolet-A\u2013induced collagen crosslinking for the treatment of keratoconus","volume":"135","author":"Wollensak","year":"2003","journal-title":"Am J Ophthalmol"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"762","DOI":"10.1167\/iovs.11-8059","article-title":"Optimization model for UV-riboflavin corneal cross-linking","volume":"53","author":"Schumacher","year":"2012","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.jtos.2013.01.002","article-title":"Corneal crosslinking with riboflavin and ultraviolet AI Principles","volume":"11","author":"Raiskup","year":"2013","journal-title":"Ocul Surf"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1167\/iovs.12-10984","article-title":"A new tonometer\u2014the Corvis ST tonometer: clinical comparison with noncontact and Goldmann applanation tonometers","volume":"54","author":"Hong","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.jcrs.2004.10.044","article-title":"Determining in vivo biomechanical properties of the cornea with an ocular response analyzer","volume":"31","author":"Luce","year":"2005","journal-title":"J Cataract Refract Surg"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"12","DOI":"10.4103\/0974-620X.111895","article-title":"Corneal biomechanics in iatrogenic ectasia and keratoconus: a review of the literature","volume":"6","author":"Moshirfar","year":"2013","journal-title":"Oman J Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"920","DOI":"10.5301\/ejo.5000184","article-title":"Corneal biomechanical properties and anterior segment parameters in forme fruste keratoconus","volume":"22","author":"Kozobolis","year":"2012","journal-title":"Eur J Ophthalmol"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.clae.2008.12.009","article-title":"Comparison of corneal biomechanics in pre and post-refractive surgery and keratoconic eyes by Ocular Response Analyser","volume":"32","author":"Shah","year":"2009","journal-title":"Contact Lens Anterior Eye"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"1371","DOI":"10.1016\/j.jcrs.2007.04.021","article-title":"Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes","volume":"33","author":"Ortiz","year":"2007","journal-title":"J Cataract Refract Surg"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"625","DOI":"10.3928\/1081597X-20170621-03","article-title":"Comparison of corneal deformation parameters in keratoconic and normal eyes using a non-contact tonometer with a dynamic ultra-high-speed Scheimpflug camera","volume":"33","author":"Mercer","year":"2017","journal-title":"J Refract Surg"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.jbiomech.2019.06.011","article-title":"Two-year changes in corneal stiffness parameters after accelerated corneal cross-linking","volume":"93","author":"Hashemi","year":"2019","journal-title":"J Biomech"},{"key":"bib23","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12938-019-0636-3","article-title":"Novel dynamic corneal response parameters in a practice use: a critical review","volume":"18","author":"Jedzierowska","year":"2019","journal-title":"Biomed Eng Online"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"10739","DOI":"10.1364\/AO.406190","article-title":"Quantification of iris elasticity using acoustic radiation force optical coherence elastography","volume":"59","author":"Zhu","year":"2020","journal-title":"Appl Optics"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"30","DOI":"10.3390\/diagnostics13010030","article-title":"In vivo evaluation of the effects of SMILE with different amounts of stromal ablation on corneal biomechanics by optical coherence elastography","volume":"13","author":"Zhu","year":"2023","journal-title":"Diagnostics"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"647","DOI":"10.1109\/TBME.2018.2853571","article-title":"Ultrasonic microelastography to assess biomechanical properties of the cornea","volume":"66","author":"Qian","year":"2018","journal-title":"IEEE Trans Biomed Eng"},{"key":"bib27","doi-asserted-by":"publisher","first-page":"2637","DOI":"10.1109\/TBME.2020.3044066","article-title":"High frequency ultrasound elastography for estimating the viscoelastic properties of the cornea using Lamb wave model","volume":"68","author":"Weng","year":"2020","journal-title":"IEEE Trans Biomed Eng"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"1310","DOI":"10.1109\/TBME.2022.3215498","article-title":"Simultaneous assessment of the whole eye biomechanics using ultrasonic elastography","volume":"70","author":"Li","year":"2023","journal-title":"IEEE Trans Biomed Eng"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"2621","DOI":"10.1109\/TUFFC.2022.3190400","article-title":"High-frequency ultrasound elastography to assess the nonlinear elastic properties of the cornea and ciliary body","volume":"69","author":"Zhang","year":"2022","journal-title":"IEEE Trans Ultrasonics Ferroelectrics Frequency Control"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1097\/ICU.0000000000000489","article-title":"Brillouin microscopy: assessing ocular tissue biomechanics","volume":"29","author":"Yun","year":"2018","journal-title":"Curr Opin Ophthalmol"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"4490","DOI":"10.1167\/iovs.14-14450","article-title":"Biomechanical characterization of keratoconus corneas ex vivo with Brillouin microscopy","volume":"55","author":"Scarcelli","year":"2014","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"1418","DOI":"10.1167\/iovs.12-11387","article-title":"Brillouin microscopy of collagen crosslinking: noncontact depth-dependent analysis of corneal elastic modulus","volume":"54","author":"Scarcelli","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"3020","DOI":"10.1167\/iovs.18-24228","article-title":"Effects of corneal hydration on Brillouin microscopy in vivo","volume":"59","author":"Shao","year":"2018","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"721","DOI":"10.3928\/1081597X-20191004-01","article-title":"Depth-dependent reduction of biomechanical efficacy of contact lens\u2013assisted corneal cross-linking analyzed by Brillouin microscopy","volume":"35","author":"Zhang","year":"2019","journal-title":"J Refract Surg"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1109\/JSTQE.2944","article-title":"Confocal shear wave acoustic radiation force optical coherence elastography for imaging and quantification of the in vivo posterior eye","volume":"25","author":"He","year":"2018","journal-title":"IEEE Journal of Selected Topics in Quantum Electronics"},{"key":"bib36","doi-asserted-by":"publisher","first-page":"288","DOI":"10.1109\/JSTQE.2016.2524618","article-title":"Acoustic radiation force optical coherence elastography of corneal tissue","volume":"22","author":"Qu","year":"2016","journal-title":"IEEE Journal of Selected Topics in Quantum Electronics"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"106104","DOI":"10.1063\/1.5118258","article-title":"Simultaneously imaging and quantifying in vivo mechanical properties of crystalline lens and cornea using optical coherence elastography with acoustic radiation force excitation","volume":"4","author":"Li","year":"2019","journal-title":"APL Photonics"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"6567","DOI":"10.1364\/OL.410593","article-title":"Confocal air-coupled ultrasonic optical coherence elastography probe for quantitative biomechanics","volume":"45","author":"Zvietcovich","year":"2020","journal-title":"Optics Letters"},{"key":"bib39","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41598-020-69909-9","article-title":"Nearly-incompressible transverse isotropy (NITI) of cornea elasticity: model and experiments with acoustic micro-tapping OCE","volume":"10","author":"Pitre","year":"2020","journal-title":"Sci Rep"},{"key":"bib40","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1167\/tvst.9.7.4","article-title":"Depth-dependent corneal biomechanical properties in normal and keratoconic subjects by optical coherence elastography","volume":"9","author":"De Stefano","year":"2020","journal-title":"Transl Vis Sci Technol"},{"key":"bib41","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1167\/tvst.11.6.4","article-title":"Quantitative assessment of biomechanical properties of the human keratoconus cornea using acoustic radiation force optical coherence elastography","volume":"11","author":"Zhao","year":"2022","journal-title":"Transl Vis Sci Technol"},{"key":"bib42","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12886-018-0760-z","article-title":"A rabbit model of corneal Ectasia generated by treatment with collagenase type II","volume":"18","author":"Qiao","year":"2018","journal-title":"BMC Ophthalmol"},{"key":"bib43","doi-asserted-by":"publisher","first-page":"e202300074","DOI":"10.1002\/jbio.v16.8","article-title":"Novel acoustic radiation force optical coherence elastography based on ultrasmall ultrasound transducer for biomechanics evaluation of in vivo cornea","volume":"16","author":"Zhu","year":"2023","journal-title":"J Biophotonics"},{"key":"bib44","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1038\/s41467-019-12803-4","article-title":"Reverberant 3D optical coherence elastography maps the elasticity of individual corneal layers","volume":"10","author":"Zvietcovich","year":"2019","journal-title":"Nat Commun"},{"key":"bib45","doi-asserted-by":"publisher","first-page":"012007","DOI":"10.1088\/2516-1091\/ac4512","article-title":"Wave-based optical coherence elastography: the 10-year perspective","volume":"4","author":"Zvietcovich","year":"2022","journal-title":"Prog Biomed Eng"},{"key":"bib46","doi-asserted-by":"publisher","first-page":"e0281017","DOI":"10.1371\/journal.pone.0281017","article-title":"Evaluation of corneal biomechanical properties using the ocular response analyzer and the dynamic Scheimpflug-Analyzer Corvis ST in high pressure and normal pressure open-angle glaucoma patients","volume":"18","author":"Ramm","year":"2023","journal-title":"PLoS One"},{"key":"bib47","doi-asserted-by":"publisher","first-page":"595","DOI":"10.1097\/ICO.0000000000001879","article-title":"Measurement of corneal biomechanical properties in diabetes mellitus using the ocular response analyzer and the Corvis ST","volume":"38","author":"Ramm","year":"2019","journal-title":"Cornea"},{"key":"bib48","doi-asserted-by":"publisher","first-page":"3026","DOI":"10.1167\/iovs.04-0694","article-title":"Assessment of the biomechanical properties of the cornea with the ocular response analyzer in normal and keratoconic eyes","volume":"48","author":"Shah","year":"2007","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib49","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1002\/jbio.v8.4","article-title":"Optical coherence elastography for tissue characterization: a review","volume":"8","author":"Wang","year":"2015","journal-title":"J Biophotonics"},{"key":"bib50","doi-asserted-by":"publisher","first-page":"1172","DOI":"10.1364\/BOE.8.001172","article-title":"Optical coherence elastography\u2013OCT at work in tissue biomechanics","volume":"8","author":"Larin","year":"2017","journal-title":"Biomed Optic Exp"},{"key":"bib51","first-page":"1846","article-title":"Proteoglycan molecules in keratoconus corneas","volume":"32","author":"Sawaguchi","year":"1991","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib52","doi-asserted-by":"publisher","first-page":"101559","DOI":"10.1016\/j.clae.2021.101559","article-title":"Keratoconus: an updated review","volume":"45","author":"Santodomingo-Rubido","year":"2022","journal-title":"Contact Lens Anterior Eye"},{"key":"bib53","doi-asserted-by":"publisher","first-page":"17366","DOI":"10.1038\/s41598-020-74383-4","article-title":"In vivo measurement of shear modulus of the human cornea using optical coherence elastography","volume":"10","author":"Ramier","year":"2020","journal-title":"Sci Rep"},{"key":"bib54","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1001\/jamaophthalmol.2014.5641","article-title":"In vivo biomechanical mapping of normal and keratoconus corneas","volume":"133","author":"Scarcelli","year":"2015","journal-title":"JAMA Ophthalmol"},{"key":"bib55","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1016\/j.ajo.2019.02.010","article-title":"Brillouin spectroscopy of normal and keratoconus corneas","volume":"202","author":"Seiler","year":"2019","journal-title":"Am J Ophthalmol"},{"key":"bib56","doi-asserted-by":"crossref","first-page":"105001","DOI":"10.1117\/1.JBO.24.10.105001","article-title":"In vivo evaluation of corneal biomechanical properties by optical coherence elastography at different cross-linking irradiances","volume":"24","author":"Zhou","year":"2019","journal-title":"J Biomed Optics"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2793379","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T16:31:07Z","timestamp":1708446667000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2793379"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,20]]},"references-count":56,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.13.2.15","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,20]]}}}