{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:56:17Z","timestamp":1789343777818,"version":"build-2803163510"},"reference-count":40,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"4","license":[{"start":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T00:00:00Z","timestamp":1713484800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2024,4,19]]},"DOI":"10.1167\/tvst.13.4.27","type":"journal-article","created":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T15:30:52Z","timestamp":1713540652000},"page":"27","source":"Crossref","is-referenced-by-count":7,"title":["Anatomical Features can Affect OCT Measures Used for Clinical Decisions and Clinical Trial Endpoints"],"prefix":"10.1167","volume":"13","author":[{"given":"Donald C.","family":"Hood","sequence":"first","affiliation":[{"name":"Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA"},{"name":"Department of Psychology, Columbia University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sol","family":"La Bruna","sequence":"additional","affiliation":[{"name":"University of Pittsburgh School of Medicine, Pittsburgh, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary","family":"Durbin","sequence":"additional","affiliation":[{"name":"Topcon Healthcare, Oakland, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Lee","sequence":"additional","affiliation":[{"name":"Topcon Healthcare, Oakland, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi S.","family":"Hsiao","sequence":"additional","affiliation":[{"name":"Topcon Healthcare, Oakland, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos G.","family":"De Moraes","sequence":"additional","affiliation":[{"name":"Department of Psychology, Columbia University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emmanouil","family":"Tsamis","sequence":"additional","affiliation":[{"name":"Bernard and Shirlee Brown Glaucoma Research Laboratory, Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University Irving Medical Center, New York, NY, USA"},{"name":"Department of Psychology, Columbia University, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"issue":"5","key":"bib1","doi-asserted-by":"publisher","first-page":"586","DOI":"10.1001\/archopht.1995.01100050054031","article-title":"Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography","volume":"113","author":"Schuman","year":"1995","journal-title":"Arch Ophthalmol"},{"issue":"7","key":"bib2","doi-asserted-by":"publisher","first-page":"1309","DOI":"10.1016\/S0161-6420(00)00168-8","article-title":"A comparison of optical coherence tomography and retinal nerve fiber layer photography for detection of nerve fiber layer damage in glaucoma","volume":"107","author":"Zangwill","year":"2000","journal-title":"Ophthalmology"},{"issue":"9","key":"bib3","first-page":"1993","article-title":"Detecting early glaucoma by assessment of retinal nerve fiber layer thickness and visual function","volume":"42","author":"Bowd","year":"2001","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"bib4","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1016\/S0002-9394(02)02003-2","article-title":"Evaluation of the glaucomatous damage on retinal nerve fiber layer thickness measured by optical coherence tomography","volume":"135","author":"Kanamori","year":"2003","journal-title":"Am J Ophthalmol"},{"issue":"2","key":"bib5","doi-asserted-by":"publisher","first-page":"228","DOI":"10.1016\/j.ajo.2003.09.004","article-title":"Identifying early glaucoma with optical coherence tomography","volume":"137","author":"Nouri-Mahdavi","year":"2004","journal-title":"Am J Ophthalmol"},{"issue":"3","key":"bib6","doi-asserted-by":"publisher","first-page":"302","DOI":"10.1097\/IJG.0b013e318032e4d4","article-title":"Glaucoma detection by stratus OCT","volume":"16","author":"Hougaard","year":"2007","journal-title":"J Glaucoma"},{"issue":"7","key":"bib7","doi-asserted-by":"publisher","first-page":"1264","DOI":"10.1016\/j.ophtha.2008.12.045","article-title":"Comparison of retinal nerve fiber layer thickness measured by Cirrus HD and Stratus optical coherence tomography","volume":"116","author":"Sung","year":"2009","journal-title":"Ophthalmology"},{"issue":"6","key":"bib8","doi-asserted-by":"publisher","first-page":"763","DOI":"10.1136\/bjo.2009.166314","article-title":"Comparison of retinal nerve fibre layer thickness measurements calculated by the optic nerve head map (NHM4) and RNFL3.45 modes of spectral-domain optical coherence tomography (RTVue-100)","volume":"94","author":"Shin","year":"2010","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"bib9","doi-asserted-by":"publisher","first-page":"47","DOI":"10.1136\/bjo.2010.196907","article-title":"Retinal nerve fibre layer and visual function loss in glaucoma: the tipping point","volume":"96","author":"Wollstein","year":"2012","journal-title":"Br J Ophthalmol"},{"issue":"9","key":"bib10","doi-asserted-by":"publisher","first-page":"1483","DOI":"10.1038\/s41433-018-0104-5","article-title":"Comparison of glaucoma-diagnostic ability between wide-field swept-source OCT retinal nerve fiber layer maps and spectral-domain OCT","volume":"32","author":"Lee","year":"2018","journal-title":"Eye (Lond)"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"849","DOI":"10.2147\/OPTH","article-title":"The development of a reference database with the Topcon 3D OCT-1 Maestro","volume":"12","author":"Chaglasian","year":"2018","journal-title":"Clin Ophthalmol"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"46","DOI":"10.1016\/j.preteyeres.2016.12.002","article-title":"Improving our understanding, and detection, of glaucomatous damage: an approach based upon optical coherence tomography (OCT)","volume":"57","author":"Hood","year":"2017","journal-title":"Prog Retin Eye Res"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"101052","DOI":"10.1016\/j.preteyeres.2022.101052","article-title":"Detecting glaucoma with only OCT: implications for the clinic, research, screening, and AI development","volume":"90","author":"Hood","year":"2022","journal-title":"Prog Retin Eye Res"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.preteyeres.2012.08.003","article-title":"Glaucomatous damage of the macula","volume":"32","author":"Hood","year":"2013","journal-title":"Prog Retin Eye Res"},{"issue":"3","key":"bib15","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1167\/tvst.11.3.18","article-title":"The OCT RNFL probability map and artifacts resembling glaucomatous damage","volume":"11","author":"La Bruna","year":"2022","journal-title":"Transl Vis Sci Technol"},{"issue":"6","key":"bib16","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1016\/j.preteyeres.2007.08.001","article-title":"A framework for comparing structural and functional measures of glaucomatous damage","volume":"26","author":"Hood","year":"2007","journal-title":"Prog Retin Eye Res"},{"issue":"5","key":"bib17","doi-asserted-by":"publisher","first-page":"333","DOI":"10.1097\/IJG.0b013e3181650f8b","article-title":"An analysis of normal variations in retinal nerve fiber layer thickness profiles measured with optical coherence tomography","volume":"17","author":"Ghadiali","year":"2008","journal-title":"J Glaucoma"},{"issue":"7","key":"bib18","doi-asserted-by":"publisher","first-page":"519","DOI":"10.1097\/IJG.0b013e3181629a02","article-title":"Blood vessel contributions to retinal nerve fiber layer thickness profiles measured with optical coherence tomography","volume":"17","author":"Hood","year":"2008","journal-title":"J Glaucoma"},{"issue":"3","key":"bib19","doi-asserted-by":"publisher","first-page":"158","DOI":"10.1097\/IJG.0b013e3181af31ec","article-title":"The location of the inferior and superior temporal blood vessels and interindividual variability of the retinal nerve fiber layer thickness","volume":"19","author":"Hood","year":"2010","journal-title":"J Glaucoma"},{"issue":"4","key":"bib20","doi-asserted-by":"publisher","first-page":"389","DOI":"10.1097\/WNO.0000000000000152","article-title":"Diagnostic features of retinal nerve fiber layer rotation in skew deviation using optical coherence tomography","volume":"34","author":"Chen","year":"2014","journal-title":"J Neuroophthalmol"},{"issue":"11","key":"bib21","doi-asserted-by":"publisher","first-page":"6320","DOI":"10.1167\/iovs.15-17450","article-title":"Influence of the retinal blood vessel topography on the variability of the retinal nerve fiber bundle trajectories in the human retina","volume":"56","author":"Qiu","year":"2015","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"4","key":"bib22","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1097\/WNO.0000000000000422","article-title":"Avoiding clinical misinterpretation and artifacts of optical coherence tomography analysis of the optic nerve, retinal nerve fiber layer, and ganglion cell layer","volume":"36","author":"Chen","year":"2016","journal-title":"J Neuroophthalmol"},{"issue":"7","key":"bib23","doi-asserted-by":"publisher","first-page":"3152","DOI":"10.1167\/iovs.16-19461","article-title":"Adjusting circumpapillary retinal nerve fiber layer profile using retinal artery position improves the structure\u2013function relationship in glaucoma","volume":"57","author":"Fujino","year":"2016","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"3","key":"bib24","doi-asserted-by":"publisher","first-page":"e211","DOI":"10.1111\/aos.2016.94.issue-3","article-title":"Impact of segmentation errors and retinal blood vessels on retinal nerve fibre layer measurements using spectral-domain optical coherence tomography","volume":"94","author":"Ye","year":"2016","journal-title":"Acta Ophthalmol"},{"issue":"8","key":"bib25","doi-asserted-by":"publisher","first-page":"671","DOI":"10.1097\/IJG.0000000000001571","article-title":"A topographic comparison of OCT minimum rim width (BMO-MRW) and circumpapillary retinal nerve fiber layer (cRNFL) thickness measures in eyes with or suspected glaucoma","volume":"29","author":"La Bruna","year":"2020","journal-title":"J Glaucoma"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"e0103","DOI":"10.37039\/1982.8551.20220103","article-title":"Identifying and understanding optical coherence tomography artifacts that may be confused with glaucoma","volume":"81","author":"Leshno","year":"2022","journal-title":"Rev Bras Oftalmol"},{"issue":"7","key":"bib27","doi-asserted-by":"publisher","first-page":"501","DOI":"10.1097\/IJG.0b013e318193c2be","article-title":"Myopia affects retinal nerve fiber layer measurements as determined by optical coherence tomography","volume":"18","author":"Rauscher","year":"2009","journal-title":"J Glaucoma"},{"issue":"1","key":"bib28","doi-asserted-by":"publisher","first-page":"115","DOI":"10.1136\/bjo.2009.162206","article-title":"Peripapillary retinal nerve fibre layer thickness profile in subjects with myopia measured using the Stratus optical coherence tomography","volume":"94","author":"Kim","year":"2010","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"bib29","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1136\/bjo.2010.196782","article-title":"The influence of axial length on retinal nerve fibre layer thickness and optic-disc size measurements by spectral-domain OCT","volume":"96","author":"Savini","year":"2012","journal-title":"Br J Ophthalmol"},{"issue":"1","key":"bib30","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1097\/OPX.0b013e3182358008","article-title":"Changes in peripapillary retinal nerve fiber layer distribution by axial length","volume":"89","author":"Yoo","year":"2012","journal-title":"Optom Vis Sci"},{"issue":"9","key":"bib31","doi-asserted-by":"publisher","first-page":"e107553","DOI":"10.1371\/journal.pone.0107553","article-title":"Determination of axial length requiring adjustment of measured circumpapillary retinal nerve fiber layer thickness for ocular magnification","volume":"9","author":"Hirasawa","year":"2014","journal-title":"PLoS One"},{"issue":"6","key":"bib32","doi-asserted-by":"publisher","first-page":"e481","DOI":"10.1111\/aos.2014.92.issue-6","article-title":"Relationship between supernormal sectors of retinal nerve fibre layer and axial length in normal eyes","volume":"92","author":"Yamashita","year":"2014","journal-title":"Acta Ophthalmol"},{"issue":"4","key":"bib33","doi-asserted-by":"publisher","first-page":"383","DOI":"10.1097\/IJG.0000000000000216","article-title":"Effects of axial length and age on circumpapillary retinal nerve fiber layer and inner macular parameters measured by 3 types of SD-OCT instruments","volume":"25","author":"Ueda","year":"2016","journal-title":"J Glaucoma"},{"issue":"9","key":"bib34","first-page":"1385","article-title":"Influence of corneal power on circumpapillary retinal nerve fiber layer and optic nerve head measurements by spectral-domain optical coherence tomography","volume":"10","author":"Hirasawa","year":"2017","journal-title":"Int J Ophthalmol"},{"issue":"1","key":"bib35","doi-asserted-by":"publisher","first-page":"414","DOI":"10.1038\/s41598-017-00345-y","article-title":"The relationship between retinal nerve fibre layer thickness profiles and CorvisST tonometry measured biomechanical properties in young healthy subjects","volume":"7","author":"Matsuura","year":"2017","journal-title":"Sci Rep"},{"issue":"13","key":"bib36","doi-asserted-by":"publisher","first-page":"9","DOI":"10.1167\/tvst.9.13.9","article-title":"The influence of axial length upon the retinal ganglion cell layer of the human eye","volume":"9","author":"Chen","year":"2020","journal-title":"Transl Vis Sci Technol"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"156","DOI":"10.1016\/j.ajo.2023.01.003","article-title":"Deep optic nerve head structures associated with increasing axial length in healthy myopic eyes of moderate axial length","volume":"249","author":"Saito","year":"2023","journal-title":"Am J Ophthalmol"},{"issue":"1","key":"bib38","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1097\/IJG.0000000000000550","article-title":"Correlations between retinal nerve fiber layer thickness and axial length, peripapillary retinal tilt, optic disc size, and retinal artery position in healthy eyes","volume":"26","author":"Yamashita","year":"2017","journal-title":"J Glaucoma"},{"issue":"8","key":"bib39","doi-asserted-by":"publisher","first-page":"5481","DOI":"10.1167\/iovs.12-11008","article-title":"Relationship between position of peak retinal nerve fiber layer thickness and retinal arteries on sectoral retinal nerve fiber layer thickness","volume":"54","author":"Yamashita","year":"2013","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"5","key":"bib40","doi-asserted-by":"publisher","first-page":"e0177247","DOI":"10.1371\/journal.pone.0177247","article-title":"Structural parameters associated with location of peaks of peripapillary retinal nerve fiber layer thickness in young healthy eyes","volume":"12","author":"Yamashita","year":"2017","journal-title":"PLoS One"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2793591","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T15:30:55Z","timestamp":1713540655000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2793591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,19]]},"references-count":40,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,2]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.13.4.27","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2024,4,19]]}}}