{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T21:18:47Z","timestamp":1792012727614,"version":"4.4.0"},"reference-count":34,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"10","license":[{"start":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T00:00:00Z","timestamp":1760486400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2025,10,15]]},"DOI":"10.1167\/tvst.14.10.18","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T13:00:42Z","timestamp":1760533242000},"page":"18","source":"Crossref","is-referenced-by-count":3,"title":["The Effects of Eye Rubbing on Corneal Topography and Biomechanics in Children With Allergic Conjunctivitis"],"prefix":"10.1167","volume":"14","author":[{"given":"Xiaoguang","family":"Niu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aijiao","family":"Qin","sequence":"additional","affiliation":[{"name":"Wuhan Aier Ophthalmology Hanyang Eye Hospital, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China"},{"name":"Wuhan Aier Ophthalmology Hanyang Eye Hospital, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man","family":"Xu","sequence":"additional","affiliation":[{"name":"Wuhan Aier Ophthalmology Hanyang Eye Hospital, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanning","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Renmin Hospital of Wuhan University, Wuhan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1097\/ACI.0000000000000571","article-title":"Pathogenesis and complications of chronic eye rubbing in ocular allergy","volume":"19","author":"Ben-Eli","year":"2019","journal-title":"Curr Opin Allergy Clin Immunol"},{"key":"bib2","doi-asserted-by":"publisher","first-page":"361","DOI":"10.3390\/life14030361","article-title":"Vernal Keratoconjunctivitis: immunopathological insights and therapeutic applications of immunomodulators","volume":"14","author":"Hehar","year":"2024","journal-title":"Life"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"555","DOI":"10.1007\/s00417-012-2089-2","article-title":"Corneal biochemical features of patients with vernal keratoconjunctivitis","volume":"251","author":"Emre","year":"2013","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"407","DOI":"10.4103\/0301-4738.116063","article-title":"Ocular allergy and keratoconus","volume":"61","author":"Sharma","year":"2013","journal-title":"Indian J Ophthalmol"},{"key":"bib5","doi-asserted-by":"publisher","first-page":"365","DOI":"10.1007\/s10384-025-01193-4","article-title":"Identification of risk factors for persistent corneal edema associated with acute corneal hydrops in keratoconus","volume":"69","author":"Aichi","year":"2025","journal-title":"Jpn J Ophthalmol"},{"key":"bib6","doi-asserted-by":"publisher","first-page":"100993","DOI":"10.1016\/j.waojou.2024.100993","article-title":"Allergic disease and keratoconus: a two-sample univariable and multivariable Mendelian randomization study","volume":"17","author":"Xu","year":"2024","journal-title":"World Allergy Organ J"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"1451","DOI":"10.1007\/s10792-022-02542-9","article-title":"The association between keratoconus and the risk factors of eye rubbing, atopy and other allergic diseases (conjunctivitis, rhinitis, asthma and eczema): a meta-analysis","volume":"43","author":"Lo","year":"2023","journal-title":"Int Ophthalmol"},{"key":"bib8","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1016\/j.alit.2016.12.004","article-title":"Japanese guidelines for allergic conjunctival diseases 2017","volume":"66","author":"Takamura","year":"2017","journal-title":"Allergol Int."},{"key":"bib9","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1097\/ICO.0000000000003267","article-title":"Novel application of immunochromatographic assay for measurement of total tear immunoglobulin E","volume":"43","author":"Liu","year":"2024","journal-title":"Cornea"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3109\/09286586.2011.560747","article-title":"Prevalence and associated factors of keratoconus in Jerusalem: a cross-sectional study","volume":"18","author":"Millodot","year":"2011","journal-title":"Ophthalmic Epidemiol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"3699","DOI":"10.1007\/s10792-021-01929-4","article-title":"Comparative analysis of the morphological and biomechanical properties of normal cornea and keratoconus at different stages","volume":"41","author":"Wu","year":"2021","journal-title":"Int Ophthalmol"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"418","DOI":"10.3109\/09273948.2016.1145697","article-title":"Effect of allergic diseases on keratoconus severity","volume":"25","author":"Naderan","year":"2017","journal-title":"Ocul Immunol Inflamm"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"3443","DOI":"10.1007\/s10792-021-01908-9","article-title":"Risk factors for progression following corneal collagen crosslinking in keratoconus","volume":"41","author":"Saglik","year":"2021","journal-title":"Int Ophthalmol"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1016\/j.jcrs.2018.12.015","article-title":"Assessment of corneal biomechanical parameters in healthy and keratoconic eyes using dynamic bidirectional applanation device and dynamic Scheimpflug analyzer","volume":"45","author":"Herber","year":"2019","journal-title":"J Cataract Refract Surg"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"1311","DOI":"10.1007\/s00417-022-05916-y","article-title":"Biomechanical properties analysis of forme fruste keratoconus and subclinical keratoconus","volume":"261","author":"Huo","year":"2023","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"17","DOI":"10.1186\/s40662-021-00241-7","article-title":"Corneal biomechanical changes in allergic conjunctivitis","volume":"8","author":"Wang","year":"2021","journal-title":"Eye Vis"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"31","DOI":"10.1111\/cxo.12211","article-title":"Biomechanical properties of the keratoconic cornea: a review","volume":"98","author":"Vellara","year":"2015","journal-title":"Clin Exp Optom"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/j.exer.2007.12.002","article-title":"Assessment of the epithelium's contribution to corneal biomechanics","volume":"86","author":"Elsheikh","year":"2008","journal-title":"Exp Eye Res"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"946","DOI":"10.1097\/ICO.0000000000002344","article-title":"Measurement of in vivo biomechanical changes attributable to epithelial removal in keratoconus using a noncontact tonometer","volume":"39","author":"Ziaei","year":"2020","journal-title":"Cornea"},{"key":"bib20","doi-asserted-by":"publisher","first-page":"604","DOI":"10.3928\/1081597X-20090610-06","article-title":"Corneal epithelial thickness profile in the diagnosis of keratoconus","volume":"25","author":"Reinstein","year":"2009","journal-title":"J Refract Surg"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"1537","DOI":"10.1007\/s10792-021-02144-x","article-title":"Effect of white-to-white corneal diameter on biomechanical indices assessed by Pentacam Scheimpflug corneal tomography and corneal visualization Scheimpflug technology","volume":"42","author":"Lin","year":"2022","journal-title":"Int Ophthalmol"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"688","DOI":"10.3928\/1081597X-20200730-02","article-title":"Pentacam Scheimpflug tomography findings in Chinese patients with different corneal diameters","volume":"36","author":"Ding","year":"2020","journal-title":"J Refract Surg"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"18","DOI":"10.1186\/s40662-025-00435-3","article-title":"Early diagnosis of keratoconus using corneal biomechanics and OCT derived technologies","volume":"12","author":"Wang","year":"2025","journal-title":"Eye Vis"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"2083","DOI":"10.1007\/s10792-022-02608-8","article-title":"Corneal biomechanical properties in vernal keratoconjunctivitis and its subtypes: a preliminary study","volume":"43","author":"Zhang","year":"2023","journal-title":"Int Ophthalmol"},{"key":"bib25","first-page":"442","article-title":"Study on corneal biomechanical properties of suspicious keratoconus patients in corneal topography","volume":"55","author":"Zhang","year":"2019","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"459","DOI":"10.1186\/s12886-023-03215-6","article-title":"Corneal biomechanics in normal and subclinical keratoconus eyes","volume":"23","author":"Peyman","year":"2023","journal-title":"BMC Ophthalmol"},{"key":"bib27","first-page":"584","article-title":"Evaluation of two biomechanical stiffness indexes in the diagnosis of keratoconus and their changes after corneal collagen cross-linking surgery","volume":"58","author":"Liu","year":"2022","journal-title":"Zhonghua Yan Ke Za Zhi"},{"key":"bib28","doi-asserted-by":"publisher","first-page":"2057","DOI":"10.1007\/s00417-021-05081-8","article-title":"Eye rubbing in the aetiology of keratoconus: a systematic review and meta-analysis","volume":"259","author":"Sahebjada","year":"2021","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"999435","DOI":"10.3389\/fimmu.2022.999435","article-title":"Independent and interactive effects of eye rubbing and atopy on keratoconus","volume":"13","author":"Yang","year":"2022","journal-title":"Front Immunol"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"1204","DOI":"10.1089\/ten.tea.2016.0164","article-title":"Human corneal fibroblast pattern evolution and matrix synthesis on mechanically biased substrates","volume":"22","author":"Zareian","year":"2016","journal-title":"Tissue Eng Part A"},{"key":"bib31","doi-asserted-by":"publisher","first-page":"1168503","DOI":"10.3389\/fbioe.2023.1168503","article-title":"Effect of eye rubbing on corneal biomechanical properties in myopia and emmetropia","volume":"11","author":"Li","year":"2023","journal-title":"Front Bioeng Biotechnol"},{"key":"bib32","doi-asserted-by":"publisher","first-page":"1025","DOI":"10.1097\/ICO.0000000000001639","article-title":"Diagnostic ability of corneal shape and biomechanical parameters for detecting frank keratoconus","volume":"37","author":"Sedaghat","year":"2018","journal-title":"Cornea"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.4103\/IJO.IJO_766_24","article-title":"Combined corneal biomechanical and tomographical indices in subclinical and forme fruste keratoconus","volume":"72","author":"Ganesh","year":"2024","journal-title":"Indian J Ophthalmol"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"616","DOI":"10.3928\/1081597X-20180705-02","article-title":"Comparison of corneal tomography and a new combined tomographic biomechanical index in subclinical keratoconus","volume":"34","author":"Chan","year":"2018","journal-title":"J Refract Surg"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2810966","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T13:00:43Z","timestamp":1760533243000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2810966"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,15]]},"references-count":34,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.14.10.18","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10,15]]}}}