{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:33:52Z","timestamp":1763476432769,"version":"3.45.0"},"reference-count":27,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"11","license":[{"start":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T00:00:00Z","timestamp":1763424000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2025,11,18]]},"DOI":"10.1167\/tvst.14.11.26","type":"journal-article","created":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:30:38Z","timestamp":1763476238000},"page":"26","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of Three-Dimensional Choroidal Contour in Patients With Neovascular Age-Related Macular Degeneration and Their Fellow Eyes"],"prefix":"10.1167","volume":"14","author":[{"given":"Sumit Randhir","family":"Singh","sequence":"first","affiliation":[{"name":"Department of Vitreo-retina, Akhand Jyoti Eye Hospital, CoE Mastichak, Saran, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elham","family":"Sadeghi","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"Schulman","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katherine","family":"Du","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Priyanka","family":"Gandhi","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shankar A.","family":"Narayan","sequence":"additional","affiliation":[{"name":"Department of Vitreo-retina, Akhand Jyoti Eye Hospital, CoE Mastichak, Saran, Bihar, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Supriya","family":"Arora","sequence":"additional","affiliation":[{"name":"Bahamas Vision Centre and Princess Margaret Hospital, Nassau NP, Bahamas"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Nasar","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandeep Chandra","family":"Bollepalli","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiran Kumar","family":"Vupparaboina","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose Alain","family":"Sahel","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay","family":"Chhablani","sequence":"additional","affiliation":[{"name":"UPMC Eye Center, University of Pittsburgh, Pittsburgh, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"27","reference":[{"issue":"2","key":"bib1","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.preteyeres.2009.12.002","article-title":"The multifunctional choroid","volume":"29","author":"Nickla","year":"2010","journal-title":"Prog Retin Eye Res"},{"issue":"6","key":"bib2","doi-asserted-by":"publisher","first-page":"4","DOI":"10.1167\/iovs.64.6.4","article-title":"IMI-the dynamic choroid: new insights, challenges, and potential significance for human myopia","volume":"64","author":"Ostrin","year":"2023","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"11","key":"bib3","doi-asserted-by":"publisher","first-page":"1272","DOI":"10.1001\/jamaophthalmol.2016.3519","article-title":"Histopathological insights into choroidal vascular loss in clinically documented cases of age-related macular degeneration","volume":"134","author":"Seddon","year":"2016","journal-title":"JAMA Ophthalmol"},{"issue":"1","key":"bib4","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.neuron.2012.06.018","article-title":"Mechanisms of age-related macular degeneration","volume":"75","author":"Ambati","year":"2012","journal-title":"Neuron"},{"issue":"4","key":"bib5","doi-asserted-by":"publisher","first-page":"844","DOI":"10.1016\/j.ophtha.2012.10.036","article-title":"Clinical classification of age-related macular degeneration","volume":"120","author":"Ferris","year":"2013","journal-title":"Ophthalmology"},{"issue":"5","key":"bib6","doi-asserted-by":"publisher","first-page":"616","DOI":"10.1016\/j.ophtha.2019.11.004","article-title":"Consensus nomenclature for reporting neovascular age-related macular degeneration data: consensus on neovascular age-related macular degeneration nomenclature study group","volume":"127","author":"Spaide","year":"2020","journal-title":"Ophthalmology"},{"issue":"1","key":"bib7","doi-asserted-by":"publisher","first-page":"116","DOI":"10.1016\/j.ophtha.2007.03.008","article-title":"The natural history and prognosis of neovascular age-related macular degeneration: a systematic review of the literature and meta-analysis","volume":"115","author":"Wong","year":"2008","journal-title":"Ophthalmology"},{"issue":"11","key":"bib8","doi-asserted-by":"publisher","first-page":"1640","DOI":"10.1001\/archopht.1984.01040031330019","article-title":"Age-related macular degeneration and blindness due to neovascular maculopathy","volume":"102","author":"Ferris","year":"1984","journal-title":"Arch Ophthalmol"},{"issue":"4","key":"bib9","doi-asserted-by":"publisher","first-page":"496","DOI":"10.1016\/j.ajo.2008.05.032","article-title":"Enhanced depth imaging spectral-domain optical coherence tomography","volume":"146","author":"Spaide","year":"2008","journal-title":"Am J Ophthalmol"},{"issue":"19","key":"bib10","doi-asserted-by":"publisher","first-page":"20029","DOI":"10.1364\/OE.18.020029","article-title":"Ultrahigh speed 1050nm swept source\/Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second","volume":"18","author":"Potsaid","year":"2010","journal-title":"Opt Express"},{"issue":"2","key":"bib11","doi-asserted-by":"publisher","first-page":"167","DOI":"10.1016\/j.survophthal.2024.10.004","article-title":"Choroidal biomarkers in age-related macular degeneration","volume":"70","author":"Sadeghi","year":"2025","journal-title":"Surv Ophthalmol"},{"issue":"3","key":"bib12","doi-asserted-by":"publisher","first-page":"312","DOI":"10.1016\/j.survophthal.2018.11.002","article-title":"Choroidal imaging biomarkers","volume":"64","author":"Singh","year":"2019","journal-title":"Surv Ophthalmol"},{"issue":"8","key":"bib13","doi-asserted-by":"publisher","first-page":"4982","DOI":"10.1364\/BOE.426093","article-title":"Framework for quantitative three-dimensional choroidal vasculature analysis using optical coherence tomography","volume":"12","author":"Saxena","year":"2021","journal-title":"Biomed Opt Express"},{"issue":"5","key":"bib14","doi-asserted-by":"publisher","first-page":"865","DOI":"10.1097\/IAE.0b013e318251a3a8","article-title":"Choroidal imaging using spectral-domain optical coherence tomography","volume":"32","author":"Regatieri","year":"2012","journal-title":"Retina"},{"issue":"5","key":"bib15","doi-asserted-by":"publisher","first-page":"861","DOI":"10.3390\/diagnostics11050861","article-title":"Choroidal vascularity map in unilateral central serous chorioretinopathy: a comparison with fellow and healthy eyes","volume":"11","author":"Sahoo","year":"2021","journal-title":"Diagnostics (Basel)"},{"issue":"12","key":"bib16","doi-asserted-by":"publisher","first-page":"2795","DOI":"10.1364\/BOE.4.002795","article-title":"Automatic segmentation of choroidal thickness in optical coherence tomography","volume":"4","author":"Alonso-Caneiro","year":"2013","journal-title":"Biomed Opt Express"},{"issue":"12","key":"bib17","doi-asserted-by":"publisher","first-page":"5488","DOI":"10.3390\/app11125488","article-title":"Automatic segmentation of choroid layer using deep learning on spectral domain optical coherence tomography","volume":"11","author":"Hsia","year":"2021","journal-title":"Applied Sciences"},{"issue":"1","key":"bib18","doi-asserted-by":"publisher","first-page":"6210","DOI":"10.1038\/s41598-024-56376-9","article-title":"Three-dimensional choroidal contour mapping in healthy population","volume":"14","author":"Arora","year":"2024","journal-title":"Sci Rep"},{"issue":"7","key":"bib19","first-page":"483\u2013A0020","article-title":"Three-dimensional choroidal contour mapping in pathology: comparison with healthy controls","volume":"63","author":"Arora","year":"2022","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"1","key":"bib20","doi-asserted-by":"publisher","first-page":"8732","DOI":"10.1038\/s41598-021-88205-8","article-title":"En-face analysis of short posterior ciliary arteries crossing the sclera to choroid using wide-field swept-source optical coherence tomography","volume":"11","author":"Lejoyeux","year":"2021","journal-title":"Sci Rep"},{"issue":"3","key":"bib22","doi-asserted-by":"publisher","first-page":"325","DOI":"10.1016\/j.ajo.2010.04.018","article-title":"Choroidal thickness in normal eyes measured using Cirrus HD optical coherence tomography","volume":"150","author":"Manjunath","year":"2010","journal-title":"Am J Ophthalmol"},{"key":"bib23","doi-asserted-by":"publisher","first-page":"21090","DOI":"10.1038\/srep21090","article-title":"Choroidal vascularity index as a measure of vascular status of the choroid: measurements in healthy eyes from a population-based study","volume":"6","author":"Agrawal","year":"2016","journal-title":"Sci Rep"},{"issue":"10","key":"bib24","doi-asserted-by":"publisher","first-page":"3563","DOI":"10.1167\/iovs.18-26381","article-title":"New insights on choroidal vascularity: a comprehensive topographic approach","volume":"60","author":"Goud","year":"2019","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"100829","DOI":"10.1016\/j.preteyeres.2020.100829","article-title":"Exploring choroidal angioarchitecture in health and disease using choroidal vascularity index","volume":"77","author":"Agrawal","year":"2020","journal-title":"Prog Retin Eye Res"},{"issue":"7","key":"bib26","first-page":"6440","article-title":"Choroidal contour changes in central serous chorioretinopathy (CSCR)","volume":"65","author":"Khan","year":"2024","journal-title":"Invest Ophthalmol Vis Sci"},{"issue":"17","key":"bib27","doi-asserted-by":"publisher","first-page":"3243","DOI":"10.1038\/s41433-024-03308-6","article-title":"Fibrosis in age-related neovascular macular degeneration in the anti-VEGF era","volume":"38","author":"Armendariz","year":"2024","journal-title":"Eye"},{"key":"bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1109\/BHI58575.2023.10313450","article-title":"Accurate detection of 3D choroidal vasculature using swept-source OCT volumetric scans based on phansalkar thresholding","volume-title":"2023 IEEE EMBS International Conference on Biomedical and Health Informatics (BHI)","author":"Ibrahim","year":"2023"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2811117","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T14:30:39Z","timestamp":1763476239000},"score":1,"resource":{"primary":{"URL":"https:\/\/tvst.arvojournals.org\/article.aspx?articleid=2811117"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,18]]},"references-count":27,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2025,11,3]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.14.11.26","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11,18]]}}}