{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T13:51:49Z","timestamp":1782481909566,"version":"3.54.5"},"reference-count":38,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"6","license":[{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2026,6,26]]},"DOI":"10.1167\/tvst.15.6.34","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T13:31:47Z","timestamp":1782480707000},"page":"34","source":"Crossref","is-referenced-by-count":0,"title":["Comparison of the Ratio Between Anterior and Posterior Curvature Centered on the Thinnest Point (A\/B Ratio) in Normal and Keratoconus Eyes"],"prefix":"10.1167","volume":"15","author":[{"given":"Eszter","family":"Szalai","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, University of Pecs Medical School, Pecs, Hungary"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr","given":"Renato","family":"Ambrosio","sequence":"additional","affiliation":[{"name":"Federal University of the State of Rio de Janeiro, Ophthalmology Department, Rio de Janeiro, Brazil"},{"name":"Rio de Janeiro Corneal Tomography and Biomechanics Study Group, Rio de Janeiro, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elias","family":"Flockerzi","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Saarland University Medical Center, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Berthold","family":"Seitz","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Saarland University Medical Center, Homburg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hamed","family":"Momeni-Moghaddam","sequence":"additional","affiliation":[{"name":"Rehabilitation Sciences Research Center, Zahedan University of Medical Sciences, Zahedan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad-Reza","family":"Sedaghat","sequence":"additional","affiliation":[{"name":"Eye Research Center, Mashhad University of Medical Sciences, Mashhad, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael W.","family":"Belin","sequence":"additional","affiliation":[{"name":"University of Arizona, Department of Ophthalmology & Vision Sciences, Tucson, AZ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"bib1","doi-asserted-by":"publisher","first-page":"297","DOI":"10.1016\/S0039-6257(97)00119-7","article-title":"Keratoconus","volume":"42","author":"Rabinowitz","year":"1988","journal-title":"Surv Ophthalmol"},{"key":"bib2","first-page":"1426","article-title":"Computer-assisted corneal topography: High-resolution graphic presentation and analysis of keratoscopy","volume":"12","author":"Klyce","year":"1984","journal-title":"Invest Ophthalmol Vis Sci"},{"key":"bib3","doi-asserted-by":"publisher","first-page":"1327","DOI":"10.1016\/S0886-3350(99)00195-9","article-title":"KISA% index: a quantitative videokeratograpy algorithm embodying minimal topographic criteria for diagnosing keratoconus","volume":"25","author":"Rabinowitz","year":"1999","journal-title":"J Cataract Refract Surg"},{"key":"bib4","doi-asserted-by":"publisher","first-page":"926","DOI":"10.1002\/j.1538-9235.1997.tb04859.x","article-title":"Mathematical model of a Placido disk keratometer and its implications for recovery of corneal topography","volume":"74","author":"Rand","year":"1997","journal-title":"Optom Vis Sci"},{"key":"bib6","first-page":"5","article-title":"Corneal diagnosis and evaluation with the OCULUS Pentacam","volume":"35","author":"Belin","year":"2007","journal-title":"Highl Ophthalmol"},{"key":"bib7","doi-asserted-by":"publisher","first-page":"142","DOI":"10.1097\/00003226-199503000-00004","article-title":"On the location of the cone and the etiology of keratoconus","volume":"14","author":"Baum","year":"1995","journal-title":"Cornea"},{"issue":"11","key":"bib8","doi-asserted-by":"publisher","first-page":"1666","DOI":"10.1080\/02713683.2021.1931343","article-title":"Comparison of keratoconus cone location of different topo\/tomographical parameters","volume":"46","author":"Sedaghat","year":"2021","journal-title":"Curr Eye Res"},{"key":"bib9","doi-asserted-by":"publisher","first-page":"729","DOI":"10.1111\/j.1442-9071.2006.01395.x","article-title":"New devices and clinical implications for measuring corneal thickness","volume":"34","author":"Belin","year":"2006","journal-title":"Clin Exp Ophthalmol"},{"key":"bib10","doi-asserted-by":"publisher","first-page":"579","DOI":"10.1590\/S0004-27492006000400023","article-title":"[Corneal thickness progression from the thinnest point to the limbus: study based on a normal and a keratoconus population to create reference values] [in Portuguese]","volume":"69","author":"Luz","year":"2006","journal-title":"Arq Bras Oftalmol"},{"key":"bib11","doi-asserted-by":"publisher","first-page":"1851","DOI":"10.1016\/j.jcrs.2006.06.025","article-title":"Corneal-thickness spatial profile and corneal-volume distribution: tomographic indices to detect keratoconus","volume":"32","author":"Ambr\u00f3sio","year":"2006","journal-title":"J Cataract Refract Surg"},{"key":"bib12","doi-asserted-by":"publisher","first-page":"14267","DOI":"10.1038\/s41598-023-41062-z","article-title":"Actual anterior-posterior corneal radius ratio in eyes with prior myopic laser vision correction according to axial length","volume":"13","author":"Yoon","year":"2023","journal-title":"Sci Rep"},{"key":"bib13","doi-asserted-by":"publisher","first-page":"814","DOI":"10.1016\/j.jcrs.2009.11.012","article-title":"Corneal volume, pachymetry, and correlation of anterior and posterior corneal shape in subclinical and different states of clinical keratoconus","volume":"36","author":"Pinero","year":"2010","journal-title":"J Cataract Refract Surg"},{"key":"bib14","doi-asserted-by":"publisher","first-page":"1534","DOI":"10.1016\/j.ophtha.2008.02.020","article-title":"Sensitivity and specificity of posterior corneal elevation measured by Pentacam in discriminating keratoconus \/subclinical keratoconus","volume":"115","author":"De Sanctis","year":"2008","journal-title":"Ophthalmology"},{"key":"bib15","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1016\/j.jcrs.2007.12.036","article-title":"Comparison of and correlation between anterior and posterior corneal elevation maps in normal eyes and keratoconus-suspect eyes","volume":"34","author":"Schlegel","year":"2008","journal-title":"J Cataract Refract Surg"},{"key":"bib16","doi-asserted-by":"publisher","first-page":"e0231074","DOI":"10.1371\/journal.pone.0231074","article-title":"Anterior and posterior ratio of corneal surface areas: a novel index for detecting early stage keratoconus","volume":"15","author":"Itoi","year":"2020","journal-title":"PLoS One"},{"key":"bib17","doi-asserted-by":"publisher","first-page":"1547","DOI":"10.1007\/s00417-013-2261-3","article-title":"Comparative analysis of the relationship between anterior and posterior corneal shape analyzed by Scheimpflug photography in normal and keratoconus eyes","volume":"251","author":"Montalban","year":"2013","journal-title":"Graefes Arch Clin Exp Ophthalmol"},{"key":"bib18","doi-asserted-by":"publisher","first-page":"916","DOI":"10.1097\/ICO.0b013e3182904950","article-title":"Correlation of anterior and posterior corneal shape in keratoconus","volume":"32","author":"Montalban","year":"2013","journal-title":"Cornea"},{"key":"bib19","doi-asserted-by":"publisher","first-page":"606","DOI":"10.3928\/1081597X-20080601-09","article-title":"Intrasubject pachymetric asymmetry analysis","volume":"24","author":"Khachikian","year":"2008","journal-title":"J Refract Surg"},{"key":"bib20","doi-asserted-by":"crossref","first-page":"85","DOI":"10.5005\/jp-journals-10025-1105","article-title":"A new tomographic method of staging \/classifying keratoconus: the ABCD Grading System","volume":"3","author":"Duncan","year":"2015","journal-title":"Int J Keratoconus Ectatic Dis"},{"key":"bib21","doi-asserted-by":"publisher","first-page":"392","DOI":"10.1097\/ICL.0000000000001014","article-title":"Baseline characteristics of 1976 patients with ectatic corneal disorders at a single center from 2010 to 2021: a cross-sectional study of the Homburg Keratoconus Center","volume":"49","author":"Sideroudi","year":"2023","journal-title":"Eye Contact Lens"},{"key":"bib22","doi-asserted-by":"publisher","first-page":"1069","DOI":"10.1136\/bjophthalmol-2020-316789","article-title":"Keratocous staging by decades \u2013 a baseline ABCD classification of 1.000 patients in the Homburg Keratoconus Center (HKC)","volume":"105","author":"Flockerzi","year":"2021","journal-title":"Br J Ophthalmol"},{"key":"bib23","doi-asserted-by":"crossref","first-page":"e1135","DOI":"10.1111\/aos.15044","article-title":"Combined biomechanical and tomographic keratoconus staging: adding a biomechanical parameter to the ABCD keratoconus staging system","volume":"100","author":"Flockerzi","year":"2022","journal-title":"Acta Ophthalmol"},{"key":"bib24","doi-asserted-by":"publisher","first-page":"1431","DOI":"10.1097\/ICO.0000000000001648","article-title":"Changes in ABCD keratoconus grade following intracorneal ring implantation","volume":"37","author":"Sedaghat","year":"2018","journal-title":"Cornea"},{"key":"bib25","doi-asserted-by":"publisher","first-page":"52","DOI":"10.1097\/ICL.0000000000000595","article-title":"Anatomical and visual effects of the MyoRing implantation measured by the ABCD Keratoconus Grading System","volume":"46","author":"Sedaghat","year":"2020","journal-title":"Eye Contact Lens"},{"key":"bib26","doi-asserted-by":"publisher","first-page":"761","DOI":"10.1097\/ICO.0000000000002307","article-title":"Scheimpflug corneal densitometry changes following the intrastromal corneal ring segment implantation","volume":"39","author":"Sedaghat","year":"2020","journal-title":"Cornea."},{"key":"bib27","doi-asserted-by":"publisher","first-page":"753","DOI":"10.3928\/1081597X-20110721-01","article-title":"Novel pachymetric parameters based on corneal tomography for diagnosing keratoconus","volume":"27","author":"Ambrosio","year":"2011","journal-title":"J Refract Surg"},{"issue":"2","key":"bib28","first-page":"92","article-title":"Topometric and tomographic indices for the diagnosis of keratoconus","volume":"1","author":"Correia","year":"2012","journal-title":"Int J Kerat Ect Cor Dis"},{"key":"bib29","doi-asserted-by":"publisher","first-page":"561","DOI":"10.1093\/clinchem\/39.4.561","article-title":"Receiver-operating characteristic (ROC) plots: a fundamental evaluation tool in clinical medicine","volume":"39","author":"Zweig","year":"1993","journal-title":"Clin Chem"},{"key":"bib30","doi-asserted-by":"publisher","first-page":"848","DOI":"10.1080\/02713683.2018.1451545","article-title":"Asymmetry between left and right eyes in keratoconus patients increases with the severity of the worse eye","volume":"43","author":"Eppig","year":"2018","journal-title":"Curr Eye Res"},{"key":"bib31","first-page":"7","article-title":"Practical concepts of corneal topography","volume":"174","author":"Wilms","year":"1977","journal-title":"Optician"},{"key":"bib32","first-page":"423","article-title":"Derivation of corneal flattening factor, p-value","volume":"14","author":"Lam","year":"1994","journal-title":"Ophthalmic Physiol Opt"},{"key":"bib33","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1097\/ICO.0b013e31816485d3","article-title":"CLMI: the cone location and magnitude index","volume":"27","author":"Mahmoud","year":"2008","journal-title":"Cornea"},{"key":"bib34","doi-asserted-by":"publisher","first-page":"397","DOI":"10.3928\/1081597X-20120518-02","article-title":"Effect of topographic cone location on outcomes of corneal collagen cross-linking for keratoconus and corneal ectasia","volume":"28","author":"Greenstein","year":"2012","journal-title":"J Refract Surg"},{"key":"bib35","doi-asserted-by":"publisher","first-page":"3311","DOI":"10.1038\/s41433-021-01404-5","article-title":"Central versus paracentral cone location and outcomes of accelerated cross-linking in keratoconus patients","volume":"35","author":"Mimouni","year":"2021","journal-title":"Eye (Lond)"},{"issue":"3","key":"bib36","first-page":"177","article-title":"Pentacam corneal tomography for screening of refractive surgery candidates: a review of the literature, part I","volume":"8","author":"Motlagh","year":"2019","journal-title":"Med Hypothesis Discov Innov Ophthalmol"},{"key":"bib37","doi-asserted-by":"publisher","first-page":"151","DOI":"10.3928\/1081597X-20140218-03","article-title":"Enhanced ectasia screening (EES): the need for advanced and objective data","volume":"30","author":"Ambrosio","year":"2014","journal-title":"J Refract Surg"},{"key":"bib38","doi-asserted-by":"publisher","first-page":"610","DOI":"10.1001\/jamaophthalmol.2019.0415","article-title":"Clinical evaluation and validation of the Dutch Crosslinking for Keratoconus Score","volume":"137","author":"Wisse","year":"2019","journal-title":"JAMA Ophthalmol"},{"key":"bib5","volume-title":"Pentacam Corneal Topography in Wing M (ed): Corneal Topography in the Wavefront Era: A Guide for Clinical Application","author":"Belin","year":"2006"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/tvst.arvojournals.org\/article.aspx?doi=10.1167\/tvst.15.6.34","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T13:31:49Z","timestamp":1782480709000},"score":1,"resource":{"primary":{"URL":"http:\/\/tvst.arvojournals.org\/article.aspx?doi=10.1167\/tvst.15.6.34"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6,26]]},"references-count":38,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,6,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.15.6.34","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6,26]]}}}