{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:58:44Z","timestamp":1783468724725,"version":"3.55.0"},"reference-count":24,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"4","license":[{"start":{"date-parts":[[2018,7,9]],"date-time":"2018-07-09T00:00:00Z","timestamp":1531094400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2018,7,9]]},"DOI":"10.1167\/tvst.7.4.3","type":"journal-article","created":{"date-parts":[[2018,7,20]],"date-time":"2018-07-20T22:04:16Z","timestamp":1532124256000},"page":"3","source":"Crossref","is-referenced-by-count":14,"title":["Optical Detection of Macular Pigment Formation in Premature Infants"],"prefix":"10.1167","volume":"7","author":[{"given":"Hiroyuki","family":"Sasano","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan"},{"name":"Department of Ophthalmology, Jikei University School of Medicine, Tokyo, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akira","family":"Obana","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan"},{"name":"Department of Medical Spectroscopy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohsen","family":"Sharifzadeh","sequence":"additional","affiliation":[{"name":"Image Technologies Corporation, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul S.","family":"Bernstein","sequence":"additional","affiliation":[{"name":"Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigetoshi","family":"Okazaki","sequence":"additional","affiliation":[{"name":"Department of Medical Spectroscopy, Institute for Medical Photonics Research, Preeminent Medical Photonics Education and Research Center, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuko","family":"Gohto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiko","family":"Seto","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Seirei Hamamatsu General Hospital, Hamamatsu, Shizuoka, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Werner","family":"Gellermann","sequence":"additional","affiliation":[{"name":"Image Technologies Corporation, Salt Lake City, Utah, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"i2164-2591-7-4-3-b01","unstructured":"Bone RA, Landrum JT, Hime GW, Cains A, Zamor J. Stereochemistry of the human macular carotenoids. Invest Ophthalmol Vis Sci. 1993; 34: 2033\u20132040."},{"key":"i2164-2591-7-4-3-b02","doi-asserted-by":"crossref","unstructured":"Landrum JT, Bone RA. Lutein, zeaxanthin, and the macular pigment. Arch Biochem Biophys 2001; 385: 28\u201340.","DOI":"10.1006\/abbi.2000.2171"},{"key":"i2164-2591-7-4-3-b03","doi-asserted-by":"crossref","unstructured":"Krinsky NI, Landrum JT, Bone RA. Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu Rev Nutr. 2003; 23: 171\u2013201.","DOI":"10.1146\/annurev.nutr.23.011702.073307"},{"key":"i2164-2591-7-4-3-b04","doi-asserted-by":"crossref","unstructured":"Krinsky NI, Johnson EJ. Carotenoid actions and their relation to health and disease. Mol Aspects Med. 2005; 26: 459\u2013516.","DOI":"10.1016\/j.mam.2005.10.001"},{"key":"i2164-2591-7-4-3-b05","doi-asserted-by":"crossref","unstructured":"Nolan JM, Power R, Stringham J, et al. Enrichment of macular pigment enhances contrast sensitivity in subjects free of retinal disease: Central Retinal Enrichment Supplementation Trials - Report 1. Invest Ophthalmol Vis Sci. 2016; 57: 3429\u20133439.","DOI":"10.1167\/iovs.16-19520"},{"key":"i2164-2591-7-4-3-b06","unstructured":"Bone RA, Landrum JT, Fernandez L, Tarsis SL. Analysis of the macular pigment by HPLC: retinal distribution and age study. Invest Ophthalmol Vis Sci. 1988; 29: 843\u2013849."},{"key":"i2164-2591-7-4-3-b07","doi-asserted-by":"crossref","unstructured":"Bernstein PS, Sharifzadeh M, Liu A, et al. Blue-light reflectance imaging of macular pigment in infants and children. Invest Ophthal Vis Sci. 2013; 54: 4034\u20134040.","DOI":"10.1167\/iovs.13-11891"},{"key":"i2164-2591-7-4-3-b08","doi-asserted-by":"crossref","unstructured":"Sharifzadeh M, Bernstein PS, Gellermann W. Reflection-based imaging of macular pigment distributions in infants and children. J Biomed Opt. 2013; 18: 116001.","DOI":"10.1117\/1.JBO.18.11.116001"},{"key":"i2164-2591-7-4-3-b09","doi-asserted-by":"crossref","unstructured":"Caputo AR, Schnitzer RE, Lindquist TD, Sun S. Dilation in neonates: a protocol. Pediatrics. 1982; 69: 77\u201380.","DOI":"10.1542\/peds.69.1.77"},{"key":"i2164-2591-7-4-3-b10","unstructured":"Takeuchi A, Nagata M, Terauchi H, et al. Multicenter prospective study of retinopathy of prematurity\u2013II. Optimum timing of the first examination [article in Japanese]. J Jpn Ophthalmol Soc. 1994; 98: 679\u2013683."},{"key":"i2164-2591-7-4-3-b11","doi-asserted-by":"crossref","unstructured":"Fierson WM. Screening examination of premature infants for retinopathy of prematurity. Pediatrics. 2013; 131: 189\u2013195.","DOI":"10.1542\/peds.2012-2996"},{"key":"i2164-2591-7-4-3-b12","doi-asserted-by":"crossref","unstructured":"Henriksen BS, Chan G, Hoffman RO, et al. Interrelationships between maternal carotenoid status and newborn infant macular pigment optical density and carotenoid status. Invest Ophthal Vis Sci. 2013; 54: 5568\u20135578.","DOI":"10.1167\/iovs.13-12331"},{"key":"i2164-2591-7-4-3-b13","doi-asserted-by":"crossref","unstructured":"Vinekar A, Mangalesh S, Jayadev C, Maldonado RS, Bauer N, Toth CA. Retinal imaging of infants on spectral domain optical coherence tomography. Biomed Res Int. 2015; 2015: 782420.","DOI":"10.1155\/2015\/782420"},{"key":"i2164-2591-7-4-3-b14","doi-asserted-by":"crossref","unstructured":"Vajzovic L, Hendrickson AE, O'Connell RV, et al. Maturation of the human fovea: correlation of spectral-domain optical coherence tomography findings with histology. Am J Ophthalmol. 2012; 154: 779\u2013789.","DOI":"10.1016\/j.ajo.2012.05.004"},{"key":"i2164-2591-7-4-3-b15","doi-asserted-by":"crossref","unstructured":"Hendrickson A, Possin D, Vajzovic L, Toth CA. Histologic development of the human fovea from midgestation to maturity. Am J Ophthalmol. 2012; 154: 767\u2013778.","DOI":"10.1016\/j.ajo.2012.05.007"},{"key":"i2164-2591-7-4-3-b16","doi-asserted-by":"crossref","unstructured":"Berendschot TT, van Norren D. Objective determination of the macular pigment optical density using fundus reflectance spectroscopy. Arch Biochem Biophys. 2004; 430: 149\u2013155.","DOI":"10.1016\/j.abb.2004.04.029"},{"key":"i2164-2591-7-4-3-b17","doi-asserted-by":"crossref","unstructured":"Berendschot TT, van Norren D. Macular pigment shows ringlike structures. Invest Ophthalmol Vis Sci. 2006; 47: 709\u2013714.","DOI":"10.1167\/iovs.05-0663"},{"key":"i2164-2591-7-4-3-b18","doi-asserted-by":"crossref","unstructured":"Delori FC, Goger DG, Keilhauer C, Salvetti P, Staurenghi G. Bimodal spatial distribution of macular pigment: evidence of a gender relationship. J Opt Soc Am A Opt Image Sci Vis. 2006; 23: 521\u2013538.","DOI":"10.1364\/JOSAA.23.000521"},{"key":"i2164-2591-7-4-3-b19","unstructured":"Manzoni P, Guardione R, Bonetti P, et al. Lutein and zeaxanthin supplementation in preterm very low-birth-weight neonates in neonatal intensive care units: a multicenter randomized controlled trial. Am J Perinatol. 2013; 30: 25\u201332."},{"key":"i2164-2591-7-4-3-b20","doi-asserted-by":"crossref","unstructured":"Dani C, Lori I, Favelli F, et al. Lutein and zeaxanthin supplementation in preterm infants to prevent retinopathy of prematurity: a randomized controlled study. J Matern Fetal Neonatal Med. 2012; 25: 523\u2013527.","DOI":"10.3109\/14767058.2011.629252"},{"key":"i2164-2591-7-4-3-b21","doi-asserted-by":"crossref","unstructured":"Romagnoli C, Giannantonio C, Cota F, et al. A prospective, randomized, double blind study comparing lutein to placebo for reducing occurrence and severity of retinopathy of prematurity. J Matern Fetal Neonatal Med. 2011; 24 (Suppl 1): 147\u2013150.","DOI":"10.3109\/14767058.2011.607618"},{"key":"i2164-2591-7-4-3-b22","doi-asserted-by":"crossref","unstructured":"Maldonado RS, O'Connell RV, Sarin N, et al. Dynamics of human foveal development after premature birth. Ophthalmology. 2011; 118: 2315\u20132325.","DOI":"10.1016\/j.ophtha.2011.05.028"},{"key":"i2164-2591-7-4-3-b23","doi-asserted-by":"crossref","unstructured":"Lee AC, Maldonado RS, Sarin N, et al. Macular features from spectral-domain optical coherence tomography as an adjunct to indirect ophthalmoscopy in retinopathy of prematurity. Retina. 2011; 31: 1470\u20131482.","DOI":"10.1097\/IAE.0b013e31821dfa6d"},{"key":"i2164-2591-7-4-3-b24","doi-asserted-by":"crossref","unstructured":"Vinekar A, Avadhani K, Sivakumar M, et al. Understanding clinically undetected macular changes in early retinopathy of prematurity on spectral domain optical coherence tomography. Invest Ophthalmol Vis Sci. 2011; 52: 5183\u20135188.","DOI":"10.1167\/iovs.10-7155"}],"container-title":["Translational Vision Science & Technology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/tvst.arvojournals.org\/article.aspx?articleid=2687701","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,28]],"date-time":"2022-08-28T00:34:59Z","timestamp":1661646899000},"score":1,"resource":{"primary":{"URL":"http:\/\/tvst.arvojournals.org\/article.aspx?doi=10.1167\/tvst.7.4.3"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,9]]},"references-count":24,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2018,7,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.7.4.3","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2018,7,9]]}}}