{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T02:18:51Z","timestamp":1785377931951,"version":"3.55.0"},"reference-count":37,"publisher":"Association for Research in Vision and Ophthalmology (ARVO)","issue":"6","license":[{"start":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T00:00:00Z","timestamp":1544054400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Trans. Vis. Sci. Tech."],"published-print":{"date-parts":[[2018,12,6]]},"DOI":"10.1167\/tvst.7.6.21","type":"journal-article","created":{"date-parts":[[2018,12,6]],"date-time":"2018-12-06T22:33:18Z","timestamp":1544135598000},"page":"21","source":"Crossref","is-referenced-by-count":43,"title":["Diagnostic Performance of Macular Versus Peripapillary Vessel Parameters by Optical Coherence Tomography Angiography for Glaucoma"],"prefix":"10.1167","volume":"7","author":[{"given":"Grace M.","family":"Richter","sequence":"first","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuna","family":"Chang","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Betty","family":"Situ","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongdi","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, University of Washington, Seattle, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce","family":"Burkemper","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alena","family":"Reznik","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sahar","family":"Bedrood","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir H.","family":"Kashani","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"Varma","sequence":"additional","affiliation":[{"name":"USC Roski Eye Institute, Keck Medicine of University of Southern California, Los Angeles, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruikang K.","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Bioengineering, University of Washington, Seattle, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"27","reference":[{"key":"i2164-2591-7-6-21-b01","doi-asserted-by":"crossref","unstructured":"Quigley HA, Broman AT. The number of people with glaucoma worldwide in 2010 and 2020. Br J Ophthalmol. 2006; 90: 262\u2013267.","DOI":"10.1136\/bjo.2005.081224"},{"key":"i2164-2591-7-6-21-b02","doi-asserted-by":"crossref","unstructured":"Weinreb RN, Aung T, Medeiros FA. The pathophysiology and treatment of glaucoma: a review. JAMA. 2014; 311: 1901\u20131911.","DOI":"10.1001\/jama.2014.3192"},{"key":"i2164-2591-7-6-21-b03","doi-asserted-by":"crossref","unstructured":"Bussel II, Wollstein G, Schuman JS. OCT for glaucoma diagnosis, screening and detection of glaucoma progression. Br J Ophthalmol. 2014; 98 (suppl 2): ii15\u2013ii19.","DOI":"10.1136\/bjophthalmol-2013-304326"},{"key":"i2164-2591-7-6-21-b04","doi-asserted-by":"crossref","unstructured":"Curcio CA, Allen KA. Topography of ganglion cells in human retina. J Comp Neurol. 1990; 300: 5\u201325.","DOI":"10.1002\/cne.903000103"},{"key":"i2164-2591-7-6-21-b05","doi-asserted-by":"crossref","unstructured":"Hood DC, Raza AS, de Moraes CGV, et al. Glaucomatous damage of the macula. Prog Retin Eye Res. 2013; 32C: 1\u201321.","DOI":"10.1016\/j.preteyeres.2012.08.003"},{"key":"i2164-2591-7-6-21-b06","doi-asserted-by":"crossref","unstructured":"Leung CKS, Chan WM, Yung WH, et al. Comparison of macular and peripapillary measurements for the detection of glaucoma: an optical coherence tompgraphy study. Ophthalmology. 2205; 112: 391\u2013400.","DOI":"10.1016\/j.ophtha.2004.10.020"},{"key":"i2164-2591-7-6-21-b07","doi-asserted-by":"crossref","unstructured":"Garway-Heath DF, Lascaratos G, Bunce C, et al. The United Kingdom Glaucoma Treatment Study: a multicenter, randomized, placebo-controlled clinical trial: design and methodology. Ophthalmology. 2013; 120: 68\u201376.","DOI":"10.1016\/j.ophtha.2012.07.028"},{"key":"i2164-2591-7-6-21-b08","doi-asserted-by":"crossref","unstructured":"Flammer J, Org\u00fcl S, Costa VP, et al. The impact of ocular blood flow in glaucoma. Prog Retin Eye Res. 2002; 21: 359\u2013393.","DOI":"10.1016\/S1350-9462(02)00008-3"},{"key":"i2164-2591-7-6-21-b09","doi-asserted-by":"crossref","unstructured":"Yarmohammadi A, Zangwill LM, Diniz-Filho A, et al. Relationship between optical coherence tomography angiography vessel density and severity of visual field loss in glaucoma. Ophthalmology. 2016; 123: 2498\u20132508.","DOI":"10.1016\/j.ophtha.2016.08.041"},{"key":"i2164-2591-7-6-21-b10","doi-asserted-by":"crossref","unstructured":"Hwang JC, Konduru R, Zhang X, et al. Relationship among visual field, blood flow, and neural structure measurements in glaucoma. Invest Ophthalmol Vis Sci. 2012; 53: 3020\u20133026.","DOI":"10.1167\/iovs.11-8552"},{"key":"i2164-2591-7-6-21-b11","doi-asserted-by":"crossref","unstructured":"Mohindroo C, Ichhpujani P, Kumar S. Current imaging modalities for assessing ocular blood flow in glaucoma. J Curr Glaucoma Pract. 2016; 10: 104\u2013112.","DOI":"10.5005\/jp-journals-10008-1210"},{"key":"i2164-2591-7-6-21-b12","doi-asserted-by":"crossref","unstructured":"Chung HS, Harris A, Ciulla TA, et al. Progress in measurement of ocular blood flow and relevance to our understanding of glaucoma and age-related macular degeneration. Prog Retin Eye Res. 1999; 18: 669\u2013687.","DOI":"10.1016\/S1350-9462(98)00037-8"},{"key":"i2164-2591-7-6-21-b13","doi-asserted-by":"crossref","unstructured":"Manalastas PIC, Zangwill LM, Saunders LJ, et al. Reproducibility of optical coherence tomography angiography macular and optic nerve head vascular density in glaucoma and healthy eyes. J Glaucoma. 2017; 26.","DOI":"10.1097\/IJG.0000000000000768"},{"key":"i2164-2591-7-6-21-b14","doi-asserted-by":"crossref","unstructured":"Chen CL, Bojikian KD, Xin C, et al. Repeatability and reproducibility of optic nerve head perfusion measurements using optical coherence tomography angiography. J Biomed Opt. 2016; 21: 065002.","DOI":"10.1117\/1.JBO.21.6.065002"},{"key":"i2164-2591-7-6-21-b15","doi-asserted-by":"crossref","unstructured":"Kashani AH, Chen CL, Gahm JK, et al. Optical coherence tomography angiography: a comprehensive review of current methods and clinical applications. Prog Retin Eye Res. 2017; 60: 66\u2013100.","DOI":"10.1016\/j.preteyeres.2017.07.002"},{"key":"i2164-2591-7-6-21-b16","doi-asserted-by":"crossref","unstructured":"Jia Y, Wei E, Wang X, et al. Optical coherence tomography angiography of optic disc perfusion in glaucoma. Ophthalmology. 2014; 121: 1322\u20131332.","DOI":"10.1016\/j.ophtha.2014.01.021"},{"key":"i2164-2591-7-6-21-b17","doi-asserted-by":"crossref","unstructured":"Liu L, Jia Y, Takusagawa HL, et al. Optical coherence tomography angiography of the peripapillary retina in glaucoma. JAMA Ophthalmol. 2015; 133: 1045\u20131052.","DOI":"10.1001\/jamaophthalmol.2015.2225"},{"key":"i2164-2591-7-6-21-b18","doi-asserted-by":"crossref","unstructured":"Chen HSL, Liu CH, Wu WC, et al. Optical coherence tomography angiography of the superficial microvasculature in the macular and peripapillary areas in glaucomatous and healthy eyes. Invest Ophthalmol Vis Sci. 2017; 58: 3637\u20133645.","DOI":"10.1167\/iovs.17-21846"},{"key":"i2164-2591-7-6-21-b19","doi-asserted-by":"crossref","unstructured":"Akil H, Chopra V, Al-Sheikh M, et al. Swept-source OCT angiography imaging of the macular capillary network in glaucoma [published online ahead of print August 7, 2017]. Br J Ophthalmol . https:\/\/doi.org\/10.1136\/bjophthalmol-2016-309816.","DOI":"10.1136\/bjophthalmol-2016-309816"},{"key":"i2164-2591-7-6-21-b20","doi-asserted-by":"crossref","unstructured":"Xu H, Yu J, Kong X, et al. Macular microvasculature alterations in patients with primary open-angle glaucoma: a cross-sectional study. Medicine (Baltimore). 2016; 95: e4341.","DOI":"10.1097\/MD.0000000000004341"},{"key":"i2164-2591-7-6-21-b21","doi-asserted-by":"crossref","unstructured":"Shoji T, Zangwill LM, Akagi T, et al. Progressive macula vessel density loss in primary open-angle glaucoma: a longitudinal study. Am J Ophthalmol. 2017; 182: 107\u2013117.","DOI":"10.1016\/j.ajo.2017.07.011"},{"key":"i2164-2591-7-6-21-b22","doi-asserted-by":"crossref","unstructured":"Yarmohammadi A, Zangwill LM, Diniz-Filho A, et al. Optical coherence tomography angiography vessel density in healthy, glaucoma suspect, and glaucoma eyes. Invest Ophthalmol Vis Sci. 2016; 57 (9): OCT451\u2013OCT459.","DOI":"10.1167\/iovs.15-18944"},{"key":"i2164-2591-7-6-21-b23","doi-asserted-by":"crossref","unstructured":"Akil H, Huang AS, Francis BA, et al. Retinal vessel density from optical coherence tomography angiography to differentiate early glaucoma, pre-perimetric glaucoma and normal eyes. PLoS One. 2017; 12: e0170476.","DOI":"10.1371\/journal.pone.0170476"},{"key":"i2164-2591-7-6-21-b24","doi-asserted-by":"crossref","unstructured":"Park HY, Kim JW, Park CK. Choroidal microvasculature dropout is associated with progressive retinal nerve fiber layer thinning in glaucoma with disc hemorrhage. Ophthalmology. 2018; 125: 1003\u20131013.","DOI":"10.1016\/j.ophtha.2018.01.016"},{"key":"i2164-2591-7-6-21-b25","doi-asserted-by":"crossref","unstructured":"Moghimi S, Zangwill LM, Penteado RC, et al. Macular and optic nerve head vessel density and progressive retinal nerve fiber layer loss in glaucoma. Ophthalmology. 2018; 125: 1720\u20131728.","DOI":"10.1016\/j.ophtha.2018.05.006"},{"key":"i2164-2591-7-6-21-b26","doi-asserted-by":"crossref","unstructured":"Triolo G, Rabiolo A, Shemonski ND, et al. Optical coherence tomography angiography macular and peripapillary vessel perfusion density in healthy subjects, glaucoma suspects, and glaucoma patients. Invest Ophthalmol Vis Sci. 2017; 58: 5713\u20135722.","DOI":"10.1167\/iovs.17-22865"},{"key":"i2164-2591-7-6-21-b27","doi-asserted-by":"crossref","unstructured":"Rao HL, Pradhan ZS, Weinreb RN, et al. Regional comparisons of optical coherence tomography angiography vessel density in primary open-angle glaucoma. Am J Ophthalmol. 2016; 171 (suppl C): 75\u201383.","DOI":"10.1016\/j.ajo.2016.08.030"},{"key":"i2164-2591-7-6-21-b28","doi-asserted-by":"crossref","unstructured":"Liu L, Jia Y, Takusagawa HL, et al. Optical coherence tomography angiography of the peripapillary retina in glaucoma. JAMA Ophthalmol. 2015; 133: 1045\u20131052.","DOI":"10.1001\/jamaophthalmol.2015.2225"},{"key":"i2164-2591-7-6-21-b29","doi-asserted-by":"crossref","unstructured":"Parekh AS, Tafreshi A, Dorairaj SK, et al. Clinical applicability of the International Classification of Disease and Related Health Problems (ICD-9) glaucoma staging codes to predict disease severity in patients with open-angle glaucoma. J Glaucoma. 2014; 23: e18\u2013e22.","DOI":"10.1097\/IJG.0000000000000033"},{"key":"i2164-2591-7-6-21-b30","doi-asserted-by":"crossref","unstructured":"Chu Z, Lin J, Gao C, et al. Quantitative assessment of the retinal microvasculature using optical coherence tomography angiography. J Biomed Opt. 2016; 21: 066008.","DOI":"10.1117\/1.JBO.21.6.066008"},{"key":"i2164-2591-7-6-21-b31","doi-asserted-by":"crossref","unstructured":"DeLong ER, DeLong DM, Clarke-Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics. 1988; 44: 837\u2013845.","DOI":"10.2307\/2531595"},{"key":"i2164-2591-7-6-21-b32","doi-asserted-by":"crossref","unstructured":"Oddone F, Lucenteforte E, Michelessi M, et al. Macular versus retinal nerve fiber layer parameters for diagnosing manifest glaucoma: a systematic review of diagnostic accuracy studies. Ophthalmology. 2016; 123: 939\u2013949.","DOI":"10.1016\/j.ophtha.2015.12.041"},{"key":"i2164-2591-7-6-21-b33","doi-asserted-by":"crossref","unstructured":"Rao HL, Kadambi SV, Weinreb RN, et al. Diagnostic ability of peripapillary vessel density measurements of optical coherence tomography angiography in primary open-angle and angle-closure glaucoma. Br J Ophthalmol. 2017; 101: 1066.","DOI":"10.1136\/bjophthalmol-2016-309377"},{"key":"i2164-2591-7-6-21-b34","doi-asserted-by":"crossref","unstructured":"Yarmohammadi A, Zangwill LM, Diniz-Filho A, et al. Peripapillary and macular vessel density in patients with glaucoma and single-hemifield visual field defect. Ophthalmology. 2017; 124: 709\u2013719.","DOI":"10.1016\/j.ophtha.2017.01.004"},{"key":"i2164-2591-7-6-21-b35","doi-asserted-by":"crossref","unstructured":"Takusagawa HL, Liu L, Ma KN, et al. Projection-resolved optical coherence tomography angiography of macular retinal circulation in glaucoma. Ophthalmology. 2017; 124: 1589\u20131599.","DOI":"10.1016\/j.ophtha.2017.06.002"},{"key":"i2164-2591-7-6-21-b36","doi-asserted-by":"crossref","unstructured":"Chen CL, Zhang A, Bojikian KD, et al. Peripapillary retinal nerve fiber layer vascular microcirculation in glaucoma using optical coherence tomography-based microangiography. Invest Ophthalmol Vis Sci. 2016; 57: OCT475\u2013OCT485.","DOI":"10.1167\/iovs.15-18909"},{"key":"i2164-2591-7-6-21-b37","doi-asserted-by":"crossref","unstructured":"Choi WJ, Qin W, Chen C-L, et al. Characterizing relationship between optical microangiography signals and capillary flow using microfluidic channels. Biomed Opt Express. 2016; 7: 2709\u20132728.","DOI":"10.1364\/BOE.7.002709"}],"container-title":["Translational Vision Science &amp; Technology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/tvst.arvojournals.org\/article.aspx?articleid=2718262","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,11,6]],"date-time":"2019-11-06T23:10:07Z","timestamp":1573081807000},"score":1,"resource":{"primary":{"URL":"http:\/\/tvst.arvojournals.org\/article.aspx?doi=10.1167\/tvst.7.6.21"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12,6]]},"references-count":37,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2018,11,1]]}},"URL":"https:\/\/doi.org\/10.1167\/tvst.7.6.21","relation":{},"ISSN":["2164-2591"],"issn-type":[{"value":"2164-2591","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12,6]]}}}