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digital analysis.\n\t\t\t\t\tInt Arch Allerg Immun.\n\t\t\t\t\t2014;\n\t\t\t\t\t163:\n\t\t\t\t\t59\u201368.","DOI":"10.1159\/000355333"},{"key":"i2164-2591-8-6-31-b30","unstructured":"Zhao\n\t\t\t\t\t\t\tWJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tDuan\n\t\t\t\t\t\t\tF,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tLi\n\t\t\t\t\t\t\tZT,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tYang\n\t\t\t\t\t\t\tHJ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tHuang\n\t\t\t\t\t\t\tQ,\n\t\t\t\t\t\t\n\t\t\t\t\t\t\n\t\t\t\t\t\t\tWu\n\t\t\t\t\t\t\tKL.\n\t\t\t\t\t\t\n\t\t\t\t\t\n\t\t\t\t\tEvaluation of regional bulbar redness using an image-based objective method.\n\t\t\t\t\tInt J 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