{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T00:22:51Z","timestamp":1793838171336,"version":"4.6.1"},"reference-count":51,"publisher":"American Society for Clinical Investigation","issue":"17","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":42,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["R01HL111130"],"award-info":[{"award-number":["R01HL111130"]}]},{"name":"NIH","award":["R01CA278599"],"award-info":[{"award-number":["R01CA278599"]}]},{"name":"NIH","award":["R21AR081076"],"award-info":[{"award-number":["R21AR081076"]}]},{"name":"NIH","award":["R21AG076132"],"award-info":[{"award-number":["R21AG076132"]}]},{"name":"NIH","award":["R21AG077150"],"award-info":[{"award-number":["R21AG077150"]}]},{"name":"NIH","award":["P30CA008748"],"award-info":[{"award-number":["P30CA008748"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,9]]},"DOI":"10.1172\/jci.insight.192890","type":"journal-article","created":{"date-parts":[[2025,7,29]],"date-time":"2025-07-29T16:00:25Z","timestamp":1753804825000},"source":"Crossref","is-referenced-by-count":19,"title":["TGF-\u03b2\u2013mediated epithelial-mesenchymal transition of keratinocytes promotes fibrosis in secondary lymphedema"],"prefix":"10.1172","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-3730-852X","authenticated-orcid":false,"given":"Hyeung Ju","family":"Park","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinyeon","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ananta","family":"Sarker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8753-9783","authenticated-orcid":false,"given":"Mark G.","family":"Klang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elyn","family":"Riedel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michelle","family":"Coriddi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph H.","family":"Dayan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarit","family":"Pal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5717-697X","authenticated-orcid":false,"given":"Babak J.","family":"Mehrara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1315-7982","authenticated-orcid":false,"given":"Raghu P.","family":"Kataru","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2025,7,29]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2807"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2938-9"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-019-0322-7"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2012.01.007"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/1755-1536-5-15"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm7080201"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22010408"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1750-3639.2010.00467.x"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1203127109"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1100504"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/ctm2.758"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3390\/biology10090934"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.7555\/JBR.31.20170034"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00353"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s00403-019-01972-3"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.100594"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1096\/fj.12-222695"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.11.007"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-018-0080-4"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39104"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2005189"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18102157"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.90"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/nri1412"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2017.11.010"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20190103"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13194985"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20112767"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2004.08.007"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.b23-00291"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1400062111"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1172\/JCI66904"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2013.1728"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23020800"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1038\/nature12783"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.2183\/pjab.85.314"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.17879\/freeneuropathology-2024-5188"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.kjms.2017.03.011"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2011.12.025"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2005-0452OC"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1084\/jem.194.6.809"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00116"},{"key":"B43","doi-asserted-by":"crossref","unstructured":"Park\n              HJ\n            \n            et al\n          \n          Keratinocytes coordinate inflammatory responses and regulate development of secondary lymphedema [preprint]\n          https:\/\/doi.org\/10.1101\/2023.01.20.524936\n          Posted on bioRxiv January 21, 2023","DOI":"10.1101\/2023.01.20.524936"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18010171"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jid.2017.09.011"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00306.2011"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.283"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0049940"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2008.06.046"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.04.00120803"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2879"}],"container-title":["JCI Insight"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/insight.jci.org\/articles\/view\/192890\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,8]],"date-time":"2025-09-08T18:01:15Z","timestamp":1757354475000},"score":1,"resource":{"primary":{"URL":"https:\/\/insight.jci.org\/articles\/view\/192890"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,29]]},"references-count":51,"journal-issue":{"issue":"17","published-online":{"date-parts":[[2025,7,24]]},"published-print":{"date-parts":[[2025,9,9]]}},"alternative-id":["10.1172\/jci.insight.192890"],"URL":"https:\/\/doi.org\/10.1172\/jci.insight.192890","relation":{},"ISSN":["2379-3708"],"issn-type":[{"value":"2379-3708","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,29]]},"article-number":"e192890"}}