{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T02:05:32Z","timestamp":1782439532988,"version":"3.54.5"},"reference-count":42,"publisher":"American Society for Clinical Investigation","issue":"12","funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health Grants","doi-asserted-by":"crossref","award":["AI078908,HL111113,HL117945,R37AI052353,R01AI136041,R01HL136209,R01AI130109,"],"award-info":[{"award-number":["AI078908,HL111113,HL117945,R37AI052353,R01AI136041,R01HL136209,R01AI130109,"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health Grants","doi-asserted-by":"crossref","award":["U19AI095219"],"award-info":[{"award-number":["U19AI095219"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000968","name":"American Heart Association Grant","doi-asserted-by":"crossref","award":["15FTF25080205"],"award-info":[{"award-number":["15FTF25080205"]}],"id":[{"id":"10.13039\/100000968","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Generous contributions from the Vinik Family, the Kaye Family","award":["Generous contributions"],"award-info":[{"award-number":["Generous contributions"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,10,22]]},"DOI":"10.1172\/jci129761","type":"journal-article","created":{"date-parts":[[2019,10,21]],"date-time":"2019-10-21T22:00:46Z","timestamp":1571695246000},"page":"5169-5186","source":"Crossref","is-referenced-by-count":27,"title":["P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation"],"prefix":"10.1172","volume":"129","author":[{"given":"Jun","family":"Nagai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Balestrieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura B.","family":"Fanning","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Kyin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2240-5407","authenticated-orcid":false,"given":"Haley","family":"Cirka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junrui","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Idzko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6928-0421","authenticated-orcid":false,"given":"Andreas","family":"Zech","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9095-3109","authenticated-orcid":false,"given":"Edy Y.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick J.","family":"Brennan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua A.","family":"Boyce","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2019,10,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaf1648"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2131"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.182.2.1119"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1003020"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.03.019"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.04.012"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.12.1118"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2006.05.031"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1314768"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1403291"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.12.1035"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1126\/science.7063880"},{"key":"B13","first-page":"251","article-title":"Role of cysteinyl leukotrienes in spontaneous asthmatic responses","volume":"22","author":"Drazen","year":"1994","journal-title":"Adv Prostaglandin Thromboxane Leukot Res"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.03.048"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2004.11.014"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.2332\/allergolint.08-OA-0068"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2010.07.008"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C113.453704"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-6147(96)01035-8"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.141221498"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2005.10.003"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/nm1617"},{"key":"B23","first-page":"1","article-title":"UTP as an extracellular signaling molecule","volume":"16","author":"Lazarowski","year":"2001","journal-title":"News Physiol Sci"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1996.0739"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.180.4.2659"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201011-1762OC"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0701665"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1997.7653"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M102568200"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1124\/mol.108.046904"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1003669"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.2147\/JAA.S151849"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20100793"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1300837"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1038\/nature13807"},{"key":"B36","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/S0074-7696(04)40002-3","article-title":"Cellular distribution and functions of P2 receptor subtypes in different systems","volume":"240","author":"Burnstock","year":"2004","journal-title":"Int Rev Cytol"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-869519"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.9.6460"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.3.e48"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1084\/jem.65.2.177"},{"issue":"12","key":"B41","doi-asserted-by":"crossref","first-page":"7047","DOI":"10.4049\/jimmunol.161.12.7047","article-title":"Temporal role of chemokines in a murine model of cockroach allergen-induced airway hyperreactivity and eosinophilia","volume":"161","author":"Campbell","year":"1998","journal-title":"J Immunol"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1207816109"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/129761\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,21]],"date-time":"2023-09-21T22:45:38Z","timestamp":1695336338000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/129761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,22]]},"references-count":42,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2019,10,22]]},"published-print":{"date-parts":[[2019,10,22]]}},"alternative-id":["10.1172\/JCI129761"],"URL":"https:\/\/doi.org\/10.1172\/jci129761","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,22]]}}}