{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T07:05:27Z","timestamp":1792047927739,"version":"4.4.0"},"reference-count":58,"publisher":"American Society for Clinical Investigation","issue":"2","license":[{"start":{"date-parts":[[2022,1,18]],"date-time":"2022-01-18T00:00:00Z","timestamp":1642464000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the Japan Agency for Medical Research and Development","award":["AMED-CREST21gm1210009,21gm5010002,21zf0127003h001,JP19gm0610011,JP21lm0203006,"],"award-info":[{"award-number":["AMED-CREST21gm1210009,21gm5010002,21zf0127003h001,JP19gm0610011,JP21lm0203006,"]}]},{"name":"the Japan Agency for Medical Research and Development","award":["the Translational Research program,Strategic Promotion for practical application of INnovative medical Technology (TR-SPRINT) (JP17 Im0203006j0001)"],"award-info":[{"award-number":["the Translational Research program,Strategic Promotion for practical application of INnovative medical Technology (TR-SPRINT) (JP17 Im0203006j0001)"]}]},{"DOI":"10.13039\/501100001691","name":"the Japan Society for the Promotion of Science","doi-asserted-by":"crossref","award":["KAKENHI Grant-in-Aids for Scientific Research B (17H04187,20H03697),Grant in Aid for Scientific Research on Innovative Areas \u201cStem Cell Aging"],"award-info":[{"award-number":["KAKENHI Grant-in-Aids for Scientific Research B (17H04187,20H03697),Grant in Aid for Scientific Research on Innovative Areas \u201cStem Cell Aging"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001691","name":"the Japan Society for the Promotion of Science","doi-asserted-by":"crossref","award":["Disease (17H05642)\u201d"],"award-info":[{"award-number":["Disease (17H05642)\u201d"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001691","name":"the Japan Society for the Promotion of Science","doi-asserted-by":"crossref","award":["\u201cLipoquality (18H04673)\u201d,Grant-in-Aid for Young Scientists (B) (17K16081)"],"award-info":[{"award-number":["\u201cLipoquality (18H04673)\u201d,Grant-in-Aid for Young Scientists (B) (17K16081)"]}],"id":[{"id":"10.13039\/501100001691","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001700","name":"the Ministry of Education, Culture, Sports, Science and Technology","doi-asserted-by":"crossref","award":["World Premier International Research Center Initiative"],"award-info":[{"award-number":["World Premier International Research Center Initiative"]}],"id":[{"id":"10.13039\/501100001700","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["DFG"],"award-info":[{"award-number":["DFG"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100001659","name":"German Research Foundation","doi-asserted-by":"crossref","award":["SFB\/TRR57,SFB\/TRR219,BO3755\/3-1,BO3755\/9-1,BO3755\/13-1"],"award-info":[{"award-number":["SFB\/TRR57,SFB\/TRR219,BO3755\/3-1,BO3755\/9-1,BO3755\/13-1"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]},{"name":"the German Federal Ministries of Education and Research","award":["BMBF: STOP-FSGS-01GM1901A"],"award-info":[{"award-number":["BMBF: STOP-FSGS-01GM1901A"]}]},{"name":"Economic Affairs and Energy","award":["EMPAIA"],"award-info":[{"award-number":["EMPAIA"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,18]]},"DOI":"10.1172\/jci146071","type":"journal-article","created":{"date-parts":[[2021,11,23]],"date-time":"2021-11-23T12:30:10Z","timestamp":1637670610000},"source":"Crossref","is-referenced-by-count":119,"title":["CD153\/CD30 signaling promotes age-dependent tertiary lymphoid tissue expansion and kidney injury"],"prefix":"10.1172","volume":"132","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8417-6083","authenticated-orcid":false,"given":"Yuki","family":"Sato","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akiko","family":"Oguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Fukushima","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyoko","family":"Masuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naoya","family":"Toriu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keisuke","family":"Taniguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3426-5982","authenticated-orcid":false,"given":"Takahisa","family":"Yoshikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotong","family":"Cui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Makiko","family":"Kondo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takeshi","family":"Hosoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shota","family":"Komidori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yoko","family":"Shimizu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harumi","family":"Fujita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyi","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2362-2067","authenticated-orcid":false,"given":"Takashi","family":"Yamanashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3008-3615","authenticated-orcid":false,"given":"Jun","family":"Seita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0022-3947","authenticated-orcid":false,"given":"Takuya","family":"Yamamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5757-1109","authenticated-orcid":false,"given":"Shinya","family":"Toyokuni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3911-5708","authenticated-orcid":false,"given":"Yoko","family":"Hamazaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Masakazu","family":"Hattori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8629-6628","authenticated-orcid":false,"given":"Yasunobu","family":"Yoshikai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9921-4284","authenticated-orcid":false,"given":"Peter","family":"Boor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Floege","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiroshi","family":"Kawamoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Murakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nagahiro","family":"Minato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0339-9008","authenticated-orcid":false,"given":"Motoko","family":"Yanagita","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2022,1,18]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-019-0185-9"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2020.06.004"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-019-0144-6"},{"issue":"11","key":"B4","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.87680","article-title":"Heterogeneous fibroblasts underlie age-dependent tertiary lymphoid tissues in the kidney","volume":"1","author":"Sato","year":"2016","journal-title":"JCI Insight"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/s41385-020-0290-x"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22224"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61454-2"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007080837"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.semnephrol.2020.01.011"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00195.2018"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2017.06.030"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012080800"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2020.02.023"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-019-0180-1"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxaa006"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1500319"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1602005"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39269"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-092419-031130"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-331462"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-330530"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-018-0056-8"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1172\/JCI91250"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2019.10.006"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1172\/JCI88606"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfab269"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-07492-4"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-03750-7"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abb0806"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.04.011"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0907651"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/nature20810"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0254-9"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0698-6"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2016.04.019"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1038\/s41564-018-0231-6"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-2470"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/S1471-4906(00)01829-9"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.130062"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1324-y"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0070464"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0414-6"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-019-0378-1"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2011.01067.x"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2014.02.005"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.7.4307"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.9.6316"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1312348110"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1500368"},{"issue":"8","key":"B50","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.92943","article-title":"T-bet+ B cells are induced by human viral infections and dominate the HIV gp140 response","volume":"2","author":"Knox","year":"2017","journal-title":"JCI Insight"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600522"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-019-0403-9"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaw8330"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1600987"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2015.12.005"},{"issue":"8\u20139","key":"B56","doi-asserted-by":"crossref","first-page":"1756","DOI":"10.1016\/j.molimm.2009.01.015","article-title":"Notch activation in thymic epithelial cells induces development of thymic microenvironments","volume":"46","author":"Masuda","year":"2009","journal-title":"Mol Immunol"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btu170"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2003-4-5-p3"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/146071\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:39:20Z","timestamp":1691069960000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/146071"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,18]]},"references-count":58,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2022,1,18]]},"published-print":{"date-parts":[[2022,1,18]]}},"alternative-id":["10.1172\/JCI146071"],"URL":"https:\/\/doi.org\/10.1172\/jci146071","relation":{},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,18]]},"article-number":"e146071"}}