{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T17:46:50Z","timestamp":1793123210325,"version":"4.5.0"},"reference-count":46,"publisher":"American Society for Clinical Investigation","issue":"20","funder":[{"DOI":"10.13039\/501100001711","name":"Swiss National Science Foundation","doi-asserted-by":"crossref","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100001711","id-type":"DOI","asserted-by":"crossref"}]},{"name":", University Hospital and University of Basel","award":["-"],"award-info":[{"award-number":["-"]}]},{"DOI":"10.13039\/501100008485","name":"Swiss Academy of Medical Sciences","doi-asserted-by":"crossref","award":["-"],"award-info":[{"award-number":["-"]}],"id":[{"id":"10.13039\/501100008485","id-type":"DOI","asserted-by":"crossref"}]},{"name":"G.& J. Bangerter-Rhyner Foundation","award":["-"],"award-info":[{"award-number":["-"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,15]]},"DOI":"10.1172\/jci151800","type":"journal-article","created":{"date-parts":[[2021,9,2]],"date-time":"2021-09-02T12:01:12Z","timestamp":1630584072000},"source":"Crossref","is-referenced-by-count":37,"title":["A randomized controlled trial of the GLP-1 receptor agonist dulaglutide in primary polydipsia"],"prefix":"10.1172","volume":"131","author":[{"given":"Bettina","family":"Winzeler","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara O.","family":"Sailer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5028-5807","authenticated-orcid":false,"given":"David","family":"Coynel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Davide","family":"Zanchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0668-5675","authenticated-orcid":false,"given":"Deborah R.","family":"Vogt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine A.","family":"Urwyler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3040-4685","authenticated-orcid":false,"given":"Julie","family":"Refardt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6336-0965","authenticated-orcid":false,"given":"Mirjam","family":"Christ-Crain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2021,10,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198802183180702"},{"issue":"110","key":"B2","first-page":"235","article-title":"Compulsive water drinking","volume":"28","author":"Barlow","year":"1959","journal-title":"Q J Med"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(94)90008-6"},{"key":"B4","article-title":"Primary polydipsia in the medical and psychiatric patient: characteristics, complications and therapy","volume":"147","author":"Sailer","year":"2017","journal-title":"Swiss Med Wkly"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD003544.pub2"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/22.3.455"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.158.2.244"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3223(91)90300-B"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/0893-133X(94)00069-C"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0094112"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199205143262003"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1007\/BF00401145"},{"key":"B13","first-page":"389","article-title":"Brain-gut peptides and the control of food intake","volume":"28","author":"Smith","year":"1981","journal-title":"Adv Biochem Psychopharmacol"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1038\/379069a0"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-018-0016-2"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1159\/000094334"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3267-14.2014"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1111\/jne.12086"},{"issue":"4 pt 2","key":"B19","first-page":"R848","article-title":"Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats","volume":"271","author":"Tang-Christensen","year":"1996","journal-title":"Am J Physiol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.14.7397"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2004.04.055"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/nature25488"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.00472.2011"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-020-02394-2"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-014-0178-y"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.cobeha.2016.02.005"},{"issue":"3","key":"B27","doi-asserted-by":"crossref","DOI":"10.1111\/jne.12689","article-title":"From sensory circumventricular organs to cerebral cortex: Neural pathways controlling thirst and hunger","author":"McKinley","year":"2019","journal-title":"J Neuroendocrinol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1717646115"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2821-8"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.11.040"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2011.04.054"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/S0306-4522(96)00434-4"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9861(19990111)403:2<261::AID-CNE8>3.0.CO;2-5"},{"issue":"3","key":"B34","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1046\/j.1471-4159.1996.66030920.x","article-title":"Expression of the glucagon-like peptide-1 receptor gene in rat brain","volume":"66","author":"Alvarez","year":"1996","journal-title":"J Neurochem"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2017.06.013"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.09.010"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13369"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1111\/cen.13384"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1093\/qjmed\/hcg078"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007091042"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.1080"},{"key":"B42","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2202-13-33","article-title":"Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis","volume":"13","author":"Hunter","year":"2012","journal-title":"BMC Neurosci"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1093\/scan\/nsv063"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1097\/00005650-199603000-00003"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-4507"},{"key":"B46","unstructured":"R: A Language and Environment for Statistical Computing. Version 4.1.1. R Foundation; 2021. Accessed September 3, 2021. https:\/\/www.r-project.org\/"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/151800\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,8]],"date-time":"2023-11-08T01:46:39Z","timestamp":1699407999000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/151800"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,15]]},"references-count":46,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2021,10,15]]},"published-print":{"date-parts":[[2021,10,15]]}},"alternative-id":["10.1172\/JCI151800"],"URL":"https:\/\/doi.org\/10.1172\/jci151800","relation":{},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,15]]},"article-number":"e151800"}}