{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T17:05:10Z","timestamp":1773939910803,"version":"3.50.1"},"reference-count":78,"publisher":"American Society for Clinical Investigation","issue":"20","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"European Union\u2019s Horizon 2020 research and innovation programme","award":["733073"],"award-info":[{"award-number":["733073"]}]},{"DOI":"10.13039\/100000200","name":"U.S. Agency for International Development","doi-asserted-by":"crossref","award":["AID-OAA-C-15-00071"],"award-info":[{"award-number":["AID-OAA-C-15-00071"]}],"id":[{"id":"10.13039\/100000200","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Wellcome Trust PhD studentship","award":["203764\/Z\/16\/Z"],"award-info":[{"award-number":["203764\/Z\/16\/Z"]}]},{"DOI":"10.13039\/100010269","name":"Wellcome Trust","doi-asserted-by":"crossref","award":["206194\/Z\/17\/Z"],"award-info":[{"award-number":["206194\/Z\/17\/Z"]}],"id":[{"id":"10.13039\/100010269","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Wellcome Trust Senior Fellowship","award":["106917\/Z\/15\/Z"],"award-info":[{"award-number":["106917\/Z\/15\/Z"]}]},{"name":"Wellcome Trust and the Royal Society","award":["107668\/Z\/15\/Z"],"award-info":[{"award-number":["107668\/Z\/15\/Z"]}]},{"name":"Wellcome Trust Investigator Award","award":["222323\/Z\/21\/Z"],"award-info":[{"award-number":["222323\/Z\/21\/Z"]}]},{"DOI":"10.13039\/501100000265","name":"Medical Research Council UK","doi-asserted-by":"crossref","award":["MC_UU_00008"],"award-info":[{"award-number":["MC_UU_00008"]}],"id":[{"id":"10.13039\/501100000265","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,16]]},"DOI":"10.1172\/jci152463","type":"journal-article","created":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T12:01:09Z","timestamp":1692878469000},"source":"Crossref","is-referenced-by-count":14,"title":["A systematic analysis of the human immune response to Plasmodium vivax"],"prefix":"10.1172","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0126-5516","authenticated-orcid":false,"given":"Florian A.","family":"Bach","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana","family":"Mu\u00f1oz Sandoval","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michalina","family":"Mazurczyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9285-6639","authenticated-orcid":false,"given":"Yrene","family":"Themistocleous","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas A.","family":"Rawlinson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1479-959X","authenticated-orcid":false,"given":"Adam C.","family":"Harding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alison","family":"Kemp","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0563-4814","authenticated-orcid":false,"given":"Sarah E.","family":"Silk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0746-1945","authenticated-orcid":false,"given":"Jordan R.","family":"Barrett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7030-7839","authenticated-orcid":false,"given":"Nick J.","family":"Edwards","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alasdair","family":"Ivens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9835-1014","authenticated-orcid":false,"given":"Julian C.","family":"Rayner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7832-9824","authenticated-orcid":false,"given":"Angela M.","family":"Minassian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giorgio","family":"Napolitani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9415-1357","authenticated-orcid":false,"given":"Simon J.","family":"Draper","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philip J.","family":"Spence","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"232","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31096-7"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0008838"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc2023884"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00625-18"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-13-481"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1086\/510756"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan1078"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(97)90066-3"},{"issue":"1","key":"B9","first-page":"12","article-title":"A review of studies on immunity to vivax malaria","volume":"6","author":"Boyd","year":"1947","journal-title":"J Iowa State Med Soc"},{"issue":"6","key":"B10","first-page":"619","article-title":"[Immunity in malaria]","volume":"27","author":"Ciuca","year":"1934","journal-title":"Abstr Int Congr Trop Med Malar"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2004.70.642"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009047"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2007.76.997"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12816"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0608745104"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.05.016"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004393"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.11.055"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0117-4"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1172\/JCI134923"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.2009.09-0194"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit394"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-020518-115628"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003978"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00986-16"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.152465"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.00400"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1080\/10739680701451516"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp101"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3007240"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1128\/iai.65.10.4090-4093.1997"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens11080851"},{"key":"B34","unstructured":"McInnes L, et al. UMAP: uniform manifold approximation and projection for dimension reduction. https:\/\/arxiv.org\/abs\/1802.03426 Accessed August 24, 2023"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.a.22625"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp616"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-019-0415-5"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-018-0133-z"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1172\/JCI137265"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.09.019"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201343509"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.medj.2021.03.014"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.984323"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1186\/1479-5876-10-54"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.63838"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005975"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-017-2029-z"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1038\/icb.2010.158"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2016.07.002"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0707137"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1038\/nature11605"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.587756"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2002.tb05940.x"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.11.5954"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaq0305"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.12.1330"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv306"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy296"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.10.001"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006484"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.20-0491"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2018.09.018"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0528.2002.017412.x"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.16-0742"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1002\/cti2.1209"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.12.031"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.62800"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a029421"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.795463"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1016\/0035-9203(95)90540-5"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.a.22271"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2015.020"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.11622.1"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2018.02.010"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw777"},{"key":"B76"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1038\/nri.2017.151"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw313"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/152463\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T14:02:27Z","timestamp":1697378547000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/152463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,16]]},"references-count":78,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2023,10,16]]},"published-print":{"date-parts":[[2023,10,16]]}},"alternative-id":["10.1172\/JCI152463"],"URL":"https:\/\/doi.org\/10.1172\/jci152463","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.03.22.21252810","asserted-by":"object"}]},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,16]]},"article-number":"e152463"}}