{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T03:09:14Z","timestamp":1789096154931,"version":"build-2803163510"},"reference-count":24,"publisher":"American Society for Clinical Investigation","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2021,10,15]]},"DOI":"10.1172\/jci153640","type":"journal-article","created":{"date-parts":[[2021,10,14]],"date-time":"2021-10-14T18:06:03Z","timestamp":1634234763000},"source":"Crossref","is-referenced-by-count":19,"title":["Targeting adipose tissue to tackle NASH: SPARCL1 as an emerging player"],"prefix":"10.1172","volume":"131","author":[{"given":"Robim M.","family":"Rodrigues","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yukun","family":"Guan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2021,10,15]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30251"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.05.016"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.04.005"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.04.014"},{"issue":"3","key":"B5","first-page":"216","article-title":"Non-alcoholic fatty liver disease in lean subjects: characteristics and implications","volume":"5","author":"Kumar","year":"2017","journal-title":"J Clin Transl Hepatol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/nature06902"},{"key":"B7","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2016.00030","article-title":"Adipose tissue remodeling: its role in energy metabolism and metabolic disorders","volume":"7","author":"Choe","year":"2016","journal-title":"Front Endocrinol (Lausanne)"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20920"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01321-14"},{"key":"B10","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/139239","article-title":"Adipose tissue in obesity-related inflammation and insulin resistance: cells, cytokines, and chemokines","volume":"2013","author":"Makki","year":"2013","journal-title":"ISRN Inflamm"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/MCG.0b013e31819e9048"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1172\/JCI96324"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00579-3"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1172\/JCI45887"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1172\/JCI19246"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1687851"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1002\/hep.30525"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2016-313654"},{"key":"B19","article-title":"E-selectin-dependent inflammation and lipolysis in adipose tissue exacerbate steatosis-to-NASH progression via S100A8\/9","author":"Rodrigues","journal-title":"Cell Mol Gastroenterol Hepatol"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.12.054"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinre.2019.10.001"},{"issue":"20","key":"B22","doi-asserted-by":"crossref","DOI":"10.1172\/JCI144801","article-title":"Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2","volume":"131","author":"Liu","year":"2021","journal-title":"J Clin Invest"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0233422"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2015.05.044"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/153640\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:42:37Z","timestamp":1691084557000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/153640"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,10,15]]},"references-count":24,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2021,10,15]]},"published-print":{"date-parts":[[2021,10,15]]}},"alternative-id":["10.1172\/JCI153640"],"URL":"https:\/\/doi.org\/10.1172\/jci153640","relation":{},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,10,15]]},"article-number":"e153640"}}