{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T14:14:46Z","timestamp":1789568086513,"version":"build-2803163510"},"reference-count":59,"publisher":"American Society for Clinical Investigation","issue":"4","license":[{"start":{"date-parts":[[2023,2,15]],"date-time":"2023-02-15T00:00:00Z","timestamp":1676419200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["U01 CA244291"],"award-info":[{"award-number":["U01 CA244291"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,2,15]]},"DOI":"10.1172\/jci157907","type":"journal-article","created":{"date-parts":[[2022,12,13]],"date-time":"2022-12-13T17:01:33Z","timestamp":1670950893000},"source":"Crossref","is-referenced-by-count":22,"title":["TIGIT inhibition and lenalidomide synergistically promote antimyeloma immune responses after stem cell transplantation in mice"],"prefix":"10.1172","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1314-9264","authenticated-orcid":false,"given":"Simone A.","family":"Minnie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7021-0431","authenticated-orcid":false,"given":"Olivia G.","family":"Waltner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen S.","family":"Ensbey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stuart D.","family":"Olver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alika D.","family":"Collinge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9057-6454","authenticated-orcid":false,"given":"David P.","family":"Sester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christine R.","family":"Schmidt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel R.W.","family":"Legg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3850-0559","authenticated-orcid":false,"given":"Shuichiro","family":"Takahashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicole S.","family":"Nemychenkov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Sekiguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gregory","family":"Driessens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0311-6725","authenticated-orcid":false,"given":"Ping","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motoko","family":"Koyama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Spencer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leona A.","family":"Holmberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3007-9840","authenticated-orcid":false,"given":"Scott N.","family":"Furlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3437-9659","authenticated-orcid":false,"given":"Antiopi","family":"Varelias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey R.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2023,2,15]]},"reference":[{"issue":"1","key":"B1","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1172\/JCI98888","article-title":"Bone marrow transplantation generates T cell\u2013dependent control of myeloma in mice","volume":"129","author":"Vuckovic","year":"2019","journal-title":"J Clin Invest"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-01-825240"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-01-825265"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-15-0055"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2019.08.009"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1111\/ajco.13033"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-0200"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-20-0246"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(19)30110-3"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(19)30109-7"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-19-3673"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1002\/cyto.a.22625"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-016-0345-3"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12716"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-19-0877"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2014.10.018"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1103627"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1136\/jitc-2022-004711"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-20-0464"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V88.8.3230.bloodjournal8883230"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.11.002"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.11.043"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/ni1009"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2446"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-04632-1"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2015.65.9789"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-02-271874"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4230"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2015.7"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.84"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.833531"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2022.02.005"},{"key":"B33","article-title":"An Fc-competent anti-human TIGIT blocking antibody ociperlimab (bgb-a1217) elicits strong immune responses and potent anti-tumor efficacy in pre-clinical models","volume":"13","author":"Chen","year":"2022","journal-title":"Front Immunol"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-11-256495"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-05-1529"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2204925"},{"issue":"14","key":"B37","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.125932","article-title":"Chemotherapy followed by anti-CD137 mAb immunotherapy improves disease control in a mouse myeloma model","volume":"5","author":"Guillerey","year":"2019","journal-title":"JCI Insight"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/nature19330"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.12.021"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1172\/JCI129205"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-018-0010-1"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17991-y"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-08871-1"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.06.006"},{"issue":"1","key":"B45","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.201908224","article-title":"Modulation of the immune microenvironment by tumor-intrinsic oncogenic signaling","volume":"219","author":"Nguyen","year":"2019","journal-title":"J Cell Biol"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/bcj.2013.34"},{"issue":"11","key":"B47","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.127807","article-title":"Early alterations in stem-like\/resident T cells, innate and myeloid cells in the bone marrow in preneoplastic gammopathy","volume":"5","author":"Bailur","year":"2019","journal-title":"JCI Insight"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.07.015"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-05-850727"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-05-852798"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2008.01.007"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-01-199927"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2859"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.4402"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-0969-x"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41695-z"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.05.047"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.04.048"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.22139.1"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/157907\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:44:13Z","timestamp":1691084653000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/157907"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,15]]},"references-count":59,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2023,2,15]]},"published-print":{"date-parts":[[2023,2,15]]}},"alternative-id":["10.1172\/JCI157907"],"URL":"https:\/\/doi.org\/10.1172\/jci157907","relation":{},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,15]]},"article-number":"e157907"}}