{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T06:14:08Z","timestamp":1791094448442,"version":"4.1.0"},"reference-count":54,"publisher":"American Society for Clinical Investigation","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"published-print":{"date-parts":[[2003,1,1]]},"DOI":"10.1172\/jci200316270","type":"journal-article","created":{"date-parts":[[2003,1,3]],"date-time":"2003-01-03T00:04:32Z","timestamp":1041552272000},"page":"61-70","source":"Crossref","is-referenced-by-count":87,"title":["A novel streptococcal surface protease promotes virulence, resistance to opsonophagocytosis, and cleavage of human fibrinogen"],"prefix":"10.1172","volume":"111","author":[{"given":"Theresa O.","family":"Harris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel W.","family":"Shelver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Bohnsack","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Craig E.","family":"Rubens","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","journal-title":""},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199306243282503"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1462-5822.2000.00075.x"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1084\/jem.181.3.973"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1021\/bi992157d"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.032448299"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1172\/JCI3065"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.19.8317"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.84.20.7208"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112072200"},{"key":"B11","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/0167-4838(91)90129-N","volume":"1079","author":"Bohnsack","year":"1991","journal-title":"Biochim. Biophys. Acta."},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.66.11.4772-4778.2000"},{"key":"B13","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1093\/infdis\/157.1.91","volume":"157","author":"Martin","year":"1988","journal-title":"J. Infect. Dis."},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1995.tb02271.x"},{"key":"B15","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1128\/IAI.64.7.2387-2390.1996","volume":"64","author":"Chmouryguina","year":"1996","journal-title":"Infect. Immun."},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1993.tb01631.x"},{"key":"B17","journal-title":""},{"key":"B18","doi-asserted-by":"crossref","first-page":"229","DOI":"10.2144\/97232bm11","volume":"23","author":"Yim","year":"1997","journal-title":"Biotechniques."},{"key":"B19","doi-asserted-by":"crossref","first-page":"5633","DOI":"10.1128\/jb.174.17.5633-5638.1992","volume":"174","author":"Maguin","year":"1992","journal-title":"J. Bacteriol."},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/0147-619X(88)90016-9"},{"key":"B21","doi-asserted-by":"crossref","first-page":"3539","DOI":"10.1128\/AEM.63.9.3539-3547.1997","volume":"63","author":"Framson","year":"1997","journal-title":"Appl. Environ. Microbiol."},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009810002276"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1128\/JB.182.16.4466-4477.2000"},{"key":"B24","doi-asserted-by":"crossref","first-page":"3818","DOI":"10.1128\/IAI.64.9.3818-3826.1996","volume":"64","author":"Nizet","year":"1996","journal-title":"Infect. Immun."},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(80)90663-6"},{"key":"B26","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1128\/IAI.7.5.747-752.1973","volume":"7","author":"Ferrieri","year":"1973","journal-title":"Infect. Immun."},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009866222748"},{"key":"B28","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1042\/bj2730635","volume":"273","author":"Bohnsack","year":"1991","journal-title":"Biochem. J."},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.02099.x"},{"key":"B30","journal-title":""},{"key":"B31","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1128\/JB.121.1.354-362.1975","volume":"121","author":"Tanaka","year":"1975","journal-title":"J. Bacteriol."},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.68.9.5018-5025.2000"},{"key":"B33","doi-asserted-by":"crossref","first-page":"673","DOI":"10.4049\/jimmunol.118.2.673","volume":"118","author":"Baltimore","year":"1977","journal-title":"J. Immunol."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.071559398"},{"key":"B35","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1128\/IAI.57.6.1740-1745.1989","volume":"57","author":"Chen","year":"1989","journal-title":"Infect. Immun."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1023\/A:1002036906922"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1126\/science.286.5444.1571"},{"key":"B38","doi-asserted-by":"crossref","first-page":"5448","DOI":"10.1128\/jb.179.17.5448-5457.1997","volume":"179","author":"Belitsky","year":"1997","journal-title":"J. Bacteriol."},{"key":"B39","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1128\/MMBR.53.4.450-490.1989","volume":"53","author":"Stock","year":"1989","journal-title":"Microbiol. Rev."},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/14.11.4683"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1994.tb01271.x"},{"key":"B42","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1146\/annurev.bi.53.070184.001211","volume":"53","author":"Doolittle","year":"1984","journal-title":"Annu. Rev. Biochem."},{"key":"B43","doi-asserted-by":"crossref","first-page":"754","DOI":"10.1016\/0006-291X(76)90895-0","volume":"71","author":"Cottrell","year":"1976","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"B44","journal-title":""},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1997.tb01393.x"},{"key":"B46","journal-title":""},{"key":"B47","first-page":"217","volume":"377","author":"Maeda","year":"1996","journal-title":"Biol. Chem. Hoppe. Seyler."},{"key":"B48","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1111\/j.1574-6976.2001.tb00590.x","volume":"25","author":"L\u00e4hteenm\u00e4kia","year":"2001","journal-title":"FEMS Microbiol. Rev."},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2958.2000.01773.x"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2958.1995.tb02222.x"},{"key":"B51","doi-asserted-by":"crossref","first-page":"501","DOI":"10.1002\/pro.5560060301","volume":"6","author":"Siezen","year":"1997","journal-title":"Protein. Sci."},{"key":"B52","doi-asserted-by":"crossref","first-page":"4326","DOI":"10.1128\/IAI.67.9.4326-4333.1999","volume":"67","author":"Matsuka","year":"1999","journal-title":"Infect. Immun."},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/0968-0004(91)90096-E"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.70.6.2869-2876.2002"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jci.org\/articles\/view\/16270\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T16:47:48Z","timestamp":1691081268000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/16270"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,1,1]]},"references-count":54,"aliases":["10.1172\/jci16270"],"journal-issue":{"issue":"1","published-print":{"date-parts":[[2003,1,1]]}},"URL":"https:\/\/doi.org\/10.1172\/jci200316270","relation":{},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2003,1,1]]}}}