{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T18:25:43Z","timestamp":1787163943898,"version":"build-2736575974"},"reference-count":50,"publisher":"American Society for Clinical Investigation","issue":"20","license":[{"start":{"date-parts":[[2024,10,15]],"date-time":"2024-10-15T00:00:00Z","timestamp":1728950400000},"content-version":"vor","delay-in-days":48,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000049","name":"National Institute on Aging","doi-asserted-by":"crossref","award":["R01RF1AG068997,P01AG066603"],"award-info":[{"award-number":["R01RF1AG068997,P01AG066603"]}],"id":[{"id":"10.13039\/100000049","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,15]]},"DOI":"10.1172\/jci168155","type":"journal-article","created":{"date-parts":[[2024,8,28]],"date-time":"2024-08-28T12:39:25Z","timestamp":1724848765000},"source":"Crossref","is-referenced-by-count":15,"title":["Proton-activated chloride channel increases endplate porosity and pain in a mouse spine degeneration model"],"prefix":"10.1172","volume":"134","author":[{"given":"Peng","family":"Xue","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1009-101X","authenticated-orcid":false,"given":"Weixin","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4117-7569","authenticated-orcid":false,"given":"Junhua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiachen","family":"Chu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junying","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9122-6077","authenticated-orcid":false,"given":"Zhaozhu","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Cao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2024,8,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.14100"},{"issue":"5","key":"B2","first-page":"8","article-title":"The assessment of musculoskeletal pain","volume":"35 Suppl 107","author":"Hawker","year":"2017","journal-title":"Clin Exp Rheumatol"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.3390\/biom11081256"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1136\/practneurol-2015-001184"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-13476-9"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-021-00155-z"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.09.025"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1007\/s00774-006-0734-8"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2006.04.033"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1126\/science.aav9739"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2014.10.008"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2875-7"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108683"},{"issue":"4 suppl 92","key":"B14","first-page":"S37","article-title":"Glucocorticoids and the osteoclast","volume":"33","author":"Teitelbaum","year":"2015","journal-title":"Clin Exp Rheumatol"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.4248\/BR201301003"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2009.09.005"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.1997.12.5.753"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(01)00206-9"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600576"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2019.04.008"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.644986"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.9b00220"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1126\/science.289.5484.1504"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1172\/JCI121561"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-021-00140-6"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-26593-1"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-02988-5"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.79773"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-022-00186-0"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.85553"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.2550"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1359\/jbmr.090533"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1172\/JCI96186"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-021-01001-2"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2015-207923"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1080\/03008207.2017.1290085"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3668"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16145"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1007\/s11914-018-0489-x"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1210\/endo-119-1-119"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.5650090312"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/8756-3282(95)00486-6"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.2001.280.1.E112"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2014.12.010"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19040984"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1991.260.6.C1315"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M605865200"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.30.18636"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199902000-00003"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1186\/ar3485"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/168155\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,14]],"date-time":"2024-10-14T14:01:04Z","timestamp":1728914464000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/168155"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,28]]},"references-count":50,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2024,8,27]]},"published-print":{"date-parts":[[2024,10,15]]}},"alternative-id":["10.1172\/JCI168155"],"URL":"https:\/\/doi.org\/10.1172\/jci168155","relation":{},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,28]]},"article-number":"e168155"}}