{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T16:01:26Z","timestamp":1790352086612,"version":"4.1.0"},"reference-count":55,"publisher":"American Society for Clinical Investigation","issue":"3","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007297","name":"Office of Naval Research Global","doi-asserted-by":"crossref","award":["N000142212170"],"award-info":[{"award-number":["N000142212170"]}],"id":[{"id":"10.13039\/100007297","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL139881"],"award-info":[{"award-number":["HL139881"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL130261"],"award-info":[{"award-number":["HL130261"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL113178"],"award-info":[{"award-number":["HL113178"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL159638"],"award-info":[{"award-number":["HL159638"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL103455"],"award-info":[{"award-number":["HL103455"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL123767"],"award-info":[{"award-number":["HL123767"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000052","name":"NIH Office of the Director","doi-asserted-by":"crossref","award":["OD025008"],"award-info":[{"award-number":["OD025008"]}],"id":[{"id":"10.13039\/100000052","id-type":"DOI","asserted-by":"crossref"}]},{"name":"National Cancer Institute","award":["CA016058"],"award-info":[{"award-number":["CA016058"]}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"crossref","award":["HL166932"],"award-info":[{"award-number":["HL166932"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,1]]},"DOI":"10.1172\/jci169441","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T12:02:13Z","timestamp":1701172933000},"source":"Crossref","is-referenced-by-count":36,"title":["RAB7 deficiency impairs pulmonary artery endothelial function and promotes pulmonary hypertension"],"prefix":"10.1172","volume":"134","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9823-4013","authenticated-orcid":false,"given":"Bryce","family":"Piper","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srimathi","family":"Bogamuwa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanvir","family":"Hossain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Farkas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena","family":"Rosas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam C.","family":"Green","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Geoffrey","family":"Newcomb","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuo","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7780-5737","authenticated-orcid":false,"given":"Jose A.","family":"Ovando-Ricardez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1505-2837","authenticated-orcid":false,"given":"Jeffrey C.","family":"Horowitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aneel R.","family":"Bhagwani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3030-004X","authenticated-orcid":false,"given":"Hu","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana V.","family":"Kudryashova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7340-4784","authenticated-orcid":false,"given":"Mauricio","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana L.","family":"Mora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1965-4920","authenticated-orcid":false,"given":"Pearlly","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4405-1593","authenticated-orcid":false,"given":"Rama K.","family":"Mallampalli","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7118-6752","authenticated-orcid":false,"given":"Elena A.","family":"Goncharova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David M.","family":"Eckmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laszlo","family":"Farkas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2024,2,1]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.01887-2018"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201201-0164OC"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1172\/JCI1910"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-58083-7"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1172\/JCI136459"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aaw4974"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.090832"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0605080104"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2015.03.010"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.035889"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-019-0185-4"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.300483"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201005-0746OC"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2019.7817"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1111\/tra.12143"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.3390\/cells5030034"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.11.030"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aav0443"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2021.1946739"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-02988-3"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1096\/fj.00-0343com"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.927681"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M809277200"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2018.06.007"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1111\/tra.12003"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2018.01.004"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.03957-2020"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-3261fje"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000200180.01710.e6"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1172\/JCI36136"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.5414\/cpp47009"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/35052055"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1346-8138.2010.01004.x"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.3390\/cells7110215"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2016.11.020"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-18-2192"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2019.9955"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1238551"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1002\/path.5322"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.114.304865"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00428.2006"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200810-1662OC"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.008750"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.020617"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2015.03.019"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.33163"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.227371"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-018-0189-0"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2020.02.173"},{"key":"B50"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1096\/fj.07-8432com"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.4161\/auto.24468"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1038\/nature07619"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201707-1370OC"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00114.2010"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/169441\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,5]],"date-time":"2024-02-05T09:09:34Z","timestamp":1707124174000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/169441"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,1]]},"references-count":55,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2024,2,1]]},"published-print":{"date-parts":[[2024,2,1]]}},"alternative-id":["10.1172\/JCI169441"],"URL":"https:\/\/doi.org\/10.1172\/jci169441","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.02.03.526842","asserted-by":"object"}]},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,2,1]]},"article-number":"e169441"}}