{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:33:22Z","timestamp":1792787602297,"version":"4.5.0"},"reference-count":40,"publisher":"American Society for Clinical Investigation","issue":"20","license":[{"start":{"date-parts":[[2023,10,16]],"date-time":"2023-10-16T00:00:00Z","timestamp":1697414400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"NIH","award":["DK054759,HL09184,HL133089,HL147366,HL152960"],"award-info":[{"award-number":["DK054759,HL09184,HL133089,HL147366,HL152960"]}]},{"DOI":"10.13039\/100000897","name":"Cystic Fibrosis Foundation","doi-asserted-by":"crossref","award":["Iowa CFF Research Development Program,SINN22G0,Harry Shwachman Clinical Investigator Award"],"award-info":[{"award-number":["Iowa CFF Research Development Program,SINN22G0,Harry Shwachman Clinical Investigator Award"]}],"id":[{"id":"10.13039\/100000897","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100005564","name":"Gilead Sciences","doi-asserted-by":"crossref","award":["Gilead Sciences Research Scholars Program in Cystic Fibrosis Award"],"award-info":[{"award-number":["Gilead Sciences Research Scholars Program in Cystic Fibrosis Award"]}],"id":[{"id":"10.13039\/100005564","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100000011","name":"Howard Hughes Medical Institute","doi-asserted-by":"crossref","award":["MJW investigator"],"award-info":[{"award-number":["MJW investigator"]}],"id":[{"id":"10.13039\/100000011","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100001024","name":"Roy J. Carver Charitable Trust","doi-asserted-by":"crossref","award":["PBM supported by"],"award-info":[{"award-number":["PBM supported by"]}],"id":[{"id":"10.13039\/100001024","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,16]]},"DOI":"10.1172\/jci171268","type":"journal-article","created":{"date-parts":[[2023,8,15]],"date-time":"2023-08-15T12:04:26Z","timestamp":1692101066000},"source":"Crossref","is-referenced-by-count":60,"title":["CFTR-rich ionocytes mediate chloride absorption across airway epithelia"],"prefix":"10.1172","volume":"133","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1282-6091","authenticated-orcid":false,"given":"Lei","family":"Lei","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumba","family":"Traore","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo S.","family":"Romano Ibarra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip H.","family":"Karp","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7792-201X","authenticated-orcid":false,"given":"Tayyab","family":"Rehman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1552-3253","authenticated-orcid":false,"given":"David K.","family":"Meyerholz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph","family":"Zabner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0893-9015","authenticated-orcid":false,"given":"David A.","family":"Stoltz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9746-966X","authenticated-orcid":false,"given":"Patrick L.","family":"Sinn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1646-6206","authenticated-orcid":false,"given":"Michael J.","family":"Welsh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4067-577X","authenticated-orcid":false,"suffix":"Jr.","given":"Paul B.","family":"McCray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5535-2925","authenticated-orcid":false,"given":"Ian M.","family":"Thornell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2023,10,16]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0393-7"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0394-6"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-16239-z"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01332-7"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202008-3198OC"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2021-0499OC"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201911-2199OC"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1172\/JCI4546"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1085\/jgp.117.5.423"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1300109"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00112.2020"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3390\/genes11101169"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1172\/JCI116365"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e02-03-0134"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1113\/JP280120"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-042420-094031"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-1716.1978.tb06041.x"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1007\/BF01868818"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1007\/BF01870619"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2003.09.016"},{"key":"B21"},{"key":"B22"},{"key":"B23"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.1989.256.5.C1033"},{"issue":"6","key":"B25","first-page":"L1219","article-title":"cAMP-dependent absorption of chloride across airway epithelium","volume":"275","author":"Uyekubo","year":"1998","journal-title":"Am J Physiol"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00032.2007"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00077.2007"},{"key":"B28","article-title":"Ionocyte-specific regulation of CFTR","author":"Sato","journal-title":"Am J Respir Cell Mol Biol"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117087"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1126\/science.8211164"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/S1097-2765(00)80284-1"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00219.2019"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2119759119"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-018-05813-7"},{"key":"B35","first-page":"115","article-title":"An in vitro model of differentiated human airway epithelia. Methods for establishing primary cultures","volume":"188","author":"Karp","year":"2002","journal-title":"Methods Mol Biol"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3026"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2647"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-018-0686-x"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2010-0484OC"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.14.6003"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/171268\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T14:03:36Z","timestamp":1697378616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/171268"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,16]]},"references-count":40,"journal-issue":{"issue":"20","published-online":{"date-parts":[[2023,10,16]]},"published-print":{"date-parts":[[2023,10,16]]}},"alternative-id":["10.1172\/JCI171268"],"URL":"https:\/\/doi.org\/10.1172\/jci171268","relation":{},"ISSN":["1558-8238"],"issn-type":[{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,16]]},"article-number":"e171268"}}