{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,3,2]],"date-time":"2024-03-02T20:08:14Z","timestamp":1709410094825},"reference-count":48,"publisher":"American Society for Clinical Investigation","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"published-print":{"date-parts":[[2003,11,1]]},"DOI":"10.1172\/jci18513","type":"journal-article","created":{"date-parts":[[2008,2,29]],"date-time":"2008-02-29T22:01:44Z","timestamp":1204322504000},"page":"1372-1382","source":"Crossref","is-referenced-by-count":0,"title":["Alteration of the 4-sphingenine scaffolds of ceramides in keratinocyte-specific Arnt-deficient mice affects skin barrier function"],"prefix":"10.1172","volume":"112","author":[{"given":"Satoshi","family":"Takagi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiromasa","family":"Tojo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuhei","family":"Tomita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigetoshi","family":"Sano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoshi","family":"Itami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Hara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shintaro","family":"Inoue","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyoji","family":"Horie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gen","family":"Kondoh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ko","family":"Hosokawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frank J.","family":"Gonzalez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junji","family":"Takeda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pharmtox.40.1.519"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.14.7987"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.92.6.1936"},{"key":"B4","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1177\/002215540305100106","volume":"51","author":"Aitola","year":"2003","journal-title":"J. Histochem. Cytochem."},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4773(98)00038-0"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1006\/dbio.1997.8758"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/386403a0"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.15.8402"},{"key":"B9","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/emm.1996.9","volume":"28","author":"Steinert","year":"1996","journal-title":"Exp. Mol. Med."},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.3.1044"},{"key":"B11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/B978-0-12-024924-4.50005-5","volume":"24","author":"Elias","year":"1991","journal-title":"Adv. Lipid Res."},{"key":"B12","first-page":"759","volume":"24","author":"Wertz","year":"1983","journal-title":"J. Lipid Res."},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12265510"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1210\/me.14.10.1674"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.12.5860"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.14.7400"},{"key":"B17","first-page":"1541","volume":"125","author":"Hardman","year":"1998","journal-title":"Development."},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1111\/1523-1747.ep12461361"},{"key":"B19","doi-asserted-by":"crossref","first-page":"911","DOI":"10.1139\/o59-099","volume":"37","author":"Bligh","year":"1959","journal-title":"Can. J. Biochem. Physiol."},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/S0923-1811(97)00039-X"},{"key":"B21"},{"key":"B22","first-page":"2071","volume":"41","author":"Uchida","year":"2000","journal-title":"J. Lipid Res."},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202817200"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/18.17.4657"},{"key":"B25","first-page":"127","volume":"4","author":"Young","year":"1987","journal-title":"Photodermatol."},{"key":"B26","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/0925-4439(93)90135-N","volume":"1182","author":"Motta","year":"1993","journal-title":"Biochim. Biophys. Acta."},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/S1044-0305(02)00358-6"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0231(19980731)12:14<935::AID-RCM260>3.0.CO;2-U"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M202947200"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.274.16.11038"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R200009200"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.arplant.49.1.611"},{"key":"B33","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1093\/oxfordjournals.jbchem.a022023","volume":"123","author":"Mikami","year":"1998","journal-title":"J. Biochem. (Tokyo)."},{"key":"B34","first-page":"186","volume":"39","author":"Bouwstra","year":"1998","journal-title":"J. Lipid Res."},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2000.00846.x"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-4622(00)00234-9"},{"key":"B37","doi-asserted-by":"crossref","first-page":"2067","DOI":"10.1016\/S0006-3495(02)75554-9","volume":"82","author":"Li","year":"2002","journal-title":"Biophys. J."},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117160"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-7827(02)00028-0"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1999.00809.x"},{"key":"B41","first-page":"833","volume":"14","author":"Tolleson","year":"1999","journal-title":"Int. J. Oncol."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1096\/fj.02-0597com"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.1998.00318.x"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1126\/science.256.5060.1193"},{"key":"B45","first-page":"1194","volume":"26","author":"Gonzalez","year":"1998","journal-title":"Drug Metab. Dispos."},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.7.4451"},{"key":"B47","doi-asserted-by":"crossref","first-page":"5865","DOI":"10.1128\/MCB.16.10.5865","volume":"16","author":"Ema","year":"1996","journal-title":"Mol. Cell. Biol."},{"key":"B48","journal-title":""}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","deposited":{"date-parts":[[2017,6,18]],"date-time":"2017-06-18T05:00:54Z","timestamp":1497762054000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/18513"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,11,1]]},"references-count":48,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2003,11,1]]}},"URL":"https:\/\/doi.org\/10.1172\/jci18513","relation":{},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2003,11,1]]}}}