{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T18:28:11Z","timestamp":1791224891208,"version":"4.1.0"},"reference-count":59,"publisher":"American Society for Clinical Investigation","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"DOI":"10.1172\/jci32638","type":"journal-article","created":{"date-parts":[[2008,3,3]],"date-time":"2008-03-03T23:15:33Z","timestamp":1204586133000},"source":"Crossref","is-referenced-by-count":9,"title":["Targeted mutation of mouse skeletal muscle sodium channel produces myotonia and potassium-sensitive weakness"],"prefix":"10.1172","author":[{"given":"Lawrence J.","family":"Hayward","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanna S.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Yang","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongru","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji W.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kumudini","family":"Misra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Salajegheh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fen-fen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chie","family":"Matsuda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Valerie","family":"Reid","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didier","family":"Cros","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric P.","family":"Hoffman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Marc","family":"Renaud","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen C.","family":"Cannon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Robert H.","family":"Brown","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2008,3,1]]},"reference":[{"key":"B1","unstructured":"Lehmann-Horn, F., Rudel, R., and Jurkat-Rott, K. 2004. Nondystrophic myotonias and periodic paralyses.Myology . A.G. Engel and C. Franzini-Armstrong, editors. 3rd edition. McGraw-Hill. New York, New York, USA. 1257\u20131300."},{"key":"B2","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1146\/annurev.neuro.29.051605.112815","volume":"29","author":"Cannon","year":"2006","journal-title":"Annu. Rev. Neurosci."},{"key":"B3","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1016\/0013-4694(63)90071-3","volume":"15","author":"Creutzfeldt","year":"1963","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"B4","doi-asserted-by":"crossref","first-page":"492","DOI":"10.1172\/JCI102465","volume":"30","author":"Tyler","year":"1951","journal-title":"J. Clin. Invest."},{"key":"B5","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/0002-9343(57)90318-2","volume":"23","author":"Gamstorp","year":"1957","journal-title":"Am. J. Med."},{"key":"B6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1056\/NEJM196101052640101","volume":"264","author":"Van Der Meulen","year":"1961","journal-title":"N. Engl. J. Med."},{"key":"B7","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1093\/brain\/87.2.341","volume":"87","author":"Pearson","year":"1964","journal-title":"Brain."},{"key":"B8","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1172\/JCI106468","volume":"50","author":"Streeten","year":"1971","journal-title":"J. Clin. Invest."},{"key":"B9","doi-asserted-by":"crossref","first-page":"211","DOI":"10.3109\/00365518009095569","volume":"40","author":"Clausen","year":"1980","journal-title":"Scand. J. Clin. Lab. Invest."},{"key":"B10","doi-asserted-by":"crossref","first-page":"1647","DOI":"10.1212\/01.WNL.0000143383.91137.00","volume":"63","author":"Miller","year":"2004","journal-title":"Neurology."},{"key":"B11","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/1531-8249(200001)47:1<46::AID-ANA9>3.0.CO;2-H","volume":"47","author":"Tawil","year":"2000","journal-title":"Ann. Neurol."},{"key":"B12","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/S0140-6736(76)91340-4","volume":"1","author":"Wang","year":"1976","journal-title":"Lancet."},{"key":"B13","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1001\/archneur.1990.00530090091018","volume":"47","author":"Bradley","year":"1990","journal-title":"Arch. Neurol."},{"key":"B14","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1159\/000472351","volume":"2","author":"Plassart","year":"1994","journal-title":"Eur. J. Hum. Genet."},{"key":"B15","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1002\/mus.880060206","volume":"6","author":"Lehmann-Horn","year":"1983","journal-title":"Muscle Nerve."},{"key":"B16","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1002\/mus.880100414","volume":"10","author":"Lehmann-Horn","year":"1987","journal-title":"Muscle Nerve."},{"key":"B17","doi-asserted-by":"crossref","first-page":"1000","DOI":"10.1126\/science.2173143","volume":"250","author":"Fontaine","year":"1990","journal-title":"Science."},{"key":"B18","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1038\/354387a0","volume":"354","author":"Rojas","year":"1991","journal-title":"Nature."},{"key":"B19","doi-asserted-by":"crossref","first-page":"6341","DOI":"10.1016\/S0021-9258(18)88977-3","volume":"260","author":"Kraner","year":"1985","journal-title":"J. Biol. Chem."},{"key":"B20","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0006-3495(96)79219-6","volume":"71","author":"Cummins","year":"1996","journal-title":"Biophys. J."},{"key":"B21","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1016\/S0006-3495(97)78768-X","volume":"72","author":"Hayward","year":"1997","journal-title":"Biophys. J."},{"key":"B22","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1212\/WNL.52.7.1447","volume":"52","author":"Hayward","year":"1999","journal-title":"Neurology."},{"key":"B23","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1016\/S0006-3495(93)81045-2","volume":"65","author":"Cannon","year":"1993","journal-title":"Biophys. J."},{"key":"B24","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1085\/jgp.107.5.559","volume":"107","author":"Hayward","year":"1996","journal-title":"J. Gen. Physiol."},{"key":"B25","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1002\/mus.880121103","volume":"12","author":"Ricker","year":"1989","journal-title":"Muscle Nerve."},{"key":"B26","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1093\/brain\/awh639","volume":"129","author":"Venance","year":"2006","journal-title":"Brain."},{"key":"B27","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1002\/ana.20241","volume":"56","author":"Fournier","year":"2004","journal-title":"Ann. Neurol."},{"key":"B28","doi-asserted-by":"crossref","first-page":"356","DOI":"10.1002\/ana.20905","volume":"60","author":"Fournier","year":"2006","journal-title":"Ann. Neurol."},{"key":"B29","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1046\/j.1365-201X.2003.01158.x","volume":"178","author":"Spangenburg","year":"2003","journal-title":"Acta Physiol. Scand."},{"key":"B30","doi-asserted-by":"crossref","first-page":"2239","DOI":"10.1242\/jeb.02149","volume":"209","author":"Fluck","year":"2006","journal-title":"J. Exp. Biol."},{"key":"B31","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1146\/annurev.biochem.75.103004.142622","volume":"75","author":"Bassel-Duby","year":"2006","journal-title":"Annu. Rev. Biochem."},{"key":"B32","doi-asserted-by":"crossref","first-page":"2499","DOI":"10.1101\/gad.12.16.2499","volume":"12","author":"Chin","year":"1998","journal-title":"Genes Dev."},{"key":"B33","doi-asserted-by":"crossref","first-page":"797","DOI":"10.1038\/nature00904","volume":"418","author":"Lin","year":"2002","journal-title":"Nature."},{"key":"B34","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1093\/hmg\/1.7.521","volume":"1","author":"McClatchey","year":"1992","journal-title":"Hum. Mol. Genet."},{"key":"B35","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1006\/dbio.1993.1178","volume":"158","author":"Hughes","year":"1993","journal-title":"Dev. Biol."},{"key":"B36","doi-asserted-by":"crossref","first-page":"502","DOI":"10.1002\/mus.880110514","volume":"11","author":"Ruff","year":"1988","journal-title":"Muscle Nerve."},{"key":"B37","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1152\/jappl.1998.84.4.1395","volume":"84","author":"Cairns","year":"1998","journal-title":"J. Appl. Physiol."},{"key":"B38","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1113\/jphysiol.2003.050658","volume":"554","author":"Nielsen","year":"2004","journal-title":"J. Physiol."},{"key":"B39","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1113\/jphysiol.1981.sp013623","volume":"312","author":"Almers","year":"1981","journal-title":"J. Physiol."},{"key":"B40","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/0896-6273(93)90321-H","volume":"10","author":"Cannon","year":"1993","journal-title":"Neuron."},{"key":"B41","doi-asserted-by":"crossref","first-page":"C1351","DOI":"10.1152\/ajpcell.2000.279.5.C1351","volume":"279","author":"Gong","year":"2000","journal-title":"Am. J. Physiol. Cell Physiol"},{"key":"B42","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1002\/ana.10257","volume":"52","author":"Chinnery","year":"2002","journal-title":"Ann. Neurol."},{"key":"B43","doi-asserted-by":"crossref","first-page":"328","DOI":"10.1016\/0002-9343(61)90122-X","volume":"31","author":"Poskanzer","year":"1961","journal-title":"Am. J. Med."},{"key":"B44","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0960-8966(96)00429-4","volume":"7","author":"Kelly","year":"1997","journal-title":"Neuromuscul. Disord."},{"key":"B45","doi-asserted-by":"crossref","first-page":"1151","DOI":"10.1212\/01.wnl.0000233841.75824.0f","volume":"67","author":"Weber","year":"2006","journal-title":"Neurology."},{"key":"B46","doi-asserted-by":"crossref","first-page":"R400","DOI":"10.1152\/ajpregu.2000.278.2.R400","volume":"278","author":"Juel","year":"2000","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"B47","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1093\/brain\/85.1.121","volume":"85","author":"McArdle","year":"1962","journal-title":"Brain."},{"key":"B48","doi-asserted-by":"crossref","first-page":"6528","DOI":"10.1073\/pnas.88.15.6528","volume":"88","author":"Armstrong","year":"1991","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"B49","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1098\/rstb.1975.0011","volume":"270","author":"Hille","year":"1975","journal-title":"Philos. Trans. R. Soc. Lond. B Biol. Sci."},{"key":"B50","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1111\/j.1469-7793.1997.571bg.x","volume":"503","author":"Nielsen","year":"1997","journal-title":"J. Physiol."},{"key":"B51","doi-asserted-by":"crossref","first-page":"1269","DOI":"10.1152\/physrev.00011.2003","volume":"83","author":"Clausen","year":"2003","journal-title":"Physiol. Rev."},{"key":"B52","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1113\/jphysiol.1993.sp019960","volume":"472","author":"Clausen","year":"1993","journal-title":"J. Physiol."},{"key":"B53","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1007\/BF01837404","volume":"430","author":"Cairns","year":"1995","journal-title":"Pflugers Arch."},{"key":"B54","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1113\/jphysiol.2004.080390","volume":"563","author":"Macdonald","year":"2005","journal-title":"J. Physiol."},{"key":"B55","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1111\/j.1469-7793.2000.00325.x","volume":"527","author":"Clausen","year":"2000","journal-title":"J. Physiol."},{"key":"B56","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1152\/physrev.2000.80.4.1411","volume":"80","author":"Sejersted","year":"2000","journal-title":"Physiol. Rev."},{"key":"B57","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1152\/japplphysiol.01037.2007","volume":"104","author":"McKenna","year":"2008","journal-title":"J. Appl. Physiol."},{"key":"B58","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.0001-6772.2003.01251.x","volume":"180","author":"Clausen","year":"2004","journal-title":"Acta Physiol. Scand."},{"key":"B59","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/S0092-8674(00)81410-5","volume":"92","author":"Puigserver","year":"1998","journal-title":"Cell."}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jci.org\/articles\/view\/32638\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:05:39Z","timestamp":1691082339000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/32638"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3,1]]},"references-count":59,"URL":"https:\/\/doi.org\/10.1172\/jci32638","relation":{},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3,1]]}}}