{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:14:08Z","timestamp":1792624448343,"version":"4.5.0"},"reference-count":86,"publisher":"American Society for Clinical Investigation","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"published-print":{"date-parts":[[2008,5,1]]},"DOI":"10.1172\/jci34192","type":"journal-article","created":{"date-parts":[[2008,4,15]],"date-time":"2008-04-15T14:54:04Z","timestamp":1208271244000},"page":"1899-1910","source":"Crossref","is-referenced-by-count":375,"title":["TRPA1 is a major oxidant sensor in murine airway sensory neurons"],"prefix":"10.1172","volume":"118","author":[{"given":"Bret F.","family":"Bessac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Sivula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian A.","family":"von Hehn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasmine","family":"Escalera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lauren","family":"Cohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sven-Eric","family":"Jordt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00222.2006"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1993.tb39148.x"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1097\/00063198-200303000-00009"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1378\/chest.109.2.331"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1007\/s00408-004-2530-3"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.3200\/AEOH.58.12.746-755"},{"key":"B7","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/S0300-483X(02)00286-X","volume":"181\u2013182","author":"Winterbourn","year":"2002","journal-title":"Toxicology."},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1126\/science.1130481"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2005-0329OC"},{"key":"B10","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1080\/00039896.1977.10667258","volume":"32","author":"Barrow","year":"1977","journal-title":"Arch. Environ. Health."},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1063\/1.332129"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(84)90013-9"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1002\/jat.2550140604"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfi038"},{"key":"B15","first-page":"79","volume":"23","author":"Rupp","year":"1967","journal-title":"Int. Arch. Arbeitsmed."},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70302-1"},{"key":"B17","first-page":"141","volume":"40","author":"Shusterman","year":"2002","journal-title":"Rhinology."},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1080\/713857302"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.npep.2004.08.002"},{"key":"B20","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1152\/jappl.1999.87.6.2073","volume":"87","author":"Nodelman","year":"1999","journal-title":"J. Appl. Physiol."},{"key":"B21","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1152\/jappl.1999.86.6.1984","volume":"86","author":"Nodelman","year":"1999","journal-title":"J. Appl. Physiol."},{"key":"B22","doi-asserted-by":"crossref","first-page":"1987","DOI":"10.1152\/japplphysiol.01047.2002","volume":"94","author":"Ruan","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2005.086181"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ph.56.030194.000441"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1063\/1.370830"},{"key":"B26","first-page":"585","volume":"109(Suppl. 4)","author":"Lee","year":"2001","journal-title":"Environ. Health Perspect."},{"key":"B27","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1152\/jappl.1998.85.2.442","volume":"85","author":"Takebayashi","year":"1998","journal-title":"J. Appl. Physiol."},{"key":"B28","doi-asserted-by":"crossref","first-page":"371","DOI":"10.1152\/jappl.2001.91.1.371","volume":"91","author":"Wu","year":"2001","journal-title":"J. Appl. Physiol."},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-002-0011-4"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1034\/j.1399-3003.2000.016003570.x"},{"key":"B31","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1183\/09031936.03.00049102","volume":"21","author":"Shusterman","year":"2003","journal-title":"Eur. Respir. J."},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(02)01130-3"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2006.06.014"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/nature04886"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(03)00074-6"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.02.023"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/nature02282"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(03)00158-2"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.03.042"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1021\/bi0610909"},{"key":"B41","unstructured":"Eaton, A.D., Franson, M.A.H., American Public Health Association., American Water Works Association., and Water Environment Federation. 2005. Standard methods for the examination of water and wastewater. 21st edition. American Public Health Association. Washington, DC, USA. 1368 pp."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/S0896-6273(04)00150-3"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1038\/39807"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.0013-05.2005"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-4388(03)00101-6"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/nature02196"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.29.051605.112958"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2005.04.018"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0505356102"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2005.12.009"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.2574-05.2005"},{"key":"B52","first-page":"167","volume":"2","author":"Blasco","year":"1992","journal-title":"J. Investig. Allergol. Clin. Immunol."},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1007\/s002040050101"},{"key":"B54","doi-asserted-by":"crossref","first-page":"1563","DOI":"10.1152\/japplphysiol.00572.2002","volume":"94","author":"Morris","year":"2003","journal-title":"J. Appl. Physiol."},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(73)90148-8"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.3109\/10408449209089882"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.3109\/10408449109089879"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1007\/BF01969919"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1063\/1.1389334"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0609598103"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1038\/nature05544"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1038\/nn1692"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1093\/chemse\/27.7.593"},{"key":"B64","doi-asserted-by":"crossref","first-page":"170","DOI":"10.1016\/0304-4165(73)90198-0","volume":"313","author":"Pereira","year":"1973","journal-title":"Biochim. Biophys. Acta."},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705923104"},{"key":"B66","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.bbadis.2004.07.003","volume":"1690","author":"Hammerschmidt","year":"2004","journal-title":"Biochim. Biophys. Acta."},{"key":"B67","doi-asserted-by":"crossref","first-page":"S18","DOI":"10.1038\/nrn1434","volume":"10(Suppl.)","author":"Andersen","year":"2004","journal-title":"Nat. Med."},{"key":"B68","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1172\/JCI200317863","volume":"111","author":"Feldman","year":"2003","journal-title":"J. Clin. Invest."},{"key":"B69","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/oxfordjournals.bmb.a072970","volume":"51","author":"Mapp","year":"1995","journal-title":"Br. Med. Bull."},{"key":"B70","doi-asserted-by":"crossref","first-page":"pe19","DOI":"10.1126\/stke.3322006pe19","volume":"2006","author":"Michel","year":"2006","journal-title":"Sci. STKE."},{"key":"B71","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1111\/j.1476-5381.1989.tb14623.x","volume":"98","author":"Petersson","year":"1989","journal-title":"Br. J. Pharmacol."},{"key":"B72","first-page":"L81","volume":"258","author":"Baraniuk","year":"1990","journal-title":"Am. J. Physiol."},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2004.12.002"},{"key":"B74","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1745-9974-2-10","volume":"2","author":"McLeod","year":"2006","journal-title":"Cough."},{"key":"B75","author":"McLeod","year":"2007","journal-title":"Lung."},{"key":"B76","doi-asserted-by":"crossref","first-page":"1877","DOI":"10.1152\/jappl.1999.87.5.1877","volume":"87","author":"Morris","year":"1999","journal-title":"J. Appl. Physiol."},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0705924104"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1111\/j.1460-9568.2007.05882.x"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1016\/0041-008X(85)90376-X"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.152002699"},{"key":"B81","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1152\/jappl.1989.66.1.171","volume":"66","author":"Leikauf","year":"1989","journal-title":"J. Appl. Physiol."},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2004.01.019"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30951"},{"key":"B84","doi-asserted-by":"crossref","first-page":"3440","DOI":"10.1016\/S0021-9258(19)83641-4","volume":"260","author":"Grynkiewicz","year":"1985","journal-title":"J. Biol. Chem."},{"key":"B85","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1113\/jphysiol.1993.sp019813","volume":"469","author":"Zhou","year":"1993","journal-title":"J. Physiol."},{"key":"B86","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/S0091-679X(08)61114-0","volume":"40","author":"Kao","year":"1994","journal-title":"Methods Cell Biol."}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jci.org\/articles\/view\/34192\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:07:35Z","timestamp":1691068055000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/34192"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,5,1]]},"references-count":86,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2008,5,1]]}},"URL":"https:\/\/doi.org\/10.1172\/jci34192","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1111088.567058","asserted-by":"object"}]},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2008,5,1]]}}}