{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:52:07Z","timestamp":1792291927969,"version":"4.4.0"},"reference-count":57,"publisher":"American Society for Clinical Investigation","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"DOI":"10.1172\/jci35620","type":"journal-article","created":{"date-parts":[[2009,1,14]],"date-time":"2009-01-14T09:14:52Z","timestamp":1231924492000},"source":"Crossref","is-referenced-by-count":35,"title":["Regulator of G protein signaling 2 mediates cardiac compensation to pressure overload and antihypertrophic effects of PDE5 inhibition in mice"],"prefix":"10.1172","author":[{"given":"Eiki","family":"Takimoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimichi","family":"Koitabashi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elizabeth A.","family":"Ketner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manling","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Nagayama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Djahida","family":"Bedja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen L.","family":"Gabrielson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Blanton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David P.","family":"Siderovski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael E.","family":"Mendelsohn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Kass","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2009,1,5]]},"reference":[{"key":"B1","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1172\/JCI24178","volume":"115","author":"Dorn","year":"2005","journal-title":"J. Clin. Invest."},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1983"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.coph.2006.11.007"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2005.08.010"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000158287.49872.4e"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2006.04.003"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(02)00459-5"},{"key":"B8","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1161\/01.CIR.99.3.441","volume":"99","author":"Tamirisa","year":"1999","journal-title":"Circulation."},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.2000.1307"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.732990"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1172\/JCI6713"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.180984"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M910395199"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.26.14389"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1126\/science.280.5363.574"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/nm1101-1236"},{"key":"B17","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1172\/JCI15598","volume":"111","author":"Heximer","year":"2003","journal-title":"J. Clin. Invest."},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M507871200"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/nm958"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00103.2006"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1038\/nm1175"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/nm1215"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M506810200"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.15.8121"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00015.2005"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1124\/mol.65.5.1111"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000109415.17511.18"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1137"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90541-W"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1038\/nm805"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)80729-1"},{"key":"B32","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1172\/JCI200317700","volume":"112","author":"Yamamoto","year":"2003","journal-title":"J. Clin. Invest."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardiores.2004.03.015"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1006\/jmcc.1997.0591"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1053\/euhj.2000.2578"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-006-6066-y"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2005.08.010"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81573-1"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000033520.95242.A2"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2005.08.010"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.07.012"},{"key":"B42","doi-asserted-by":"crossref","first-page":"899","DOI":"10.5483\/BMBRep.2007.40.6.899","volume":"40","author":"Anger","year":"2007","journal-title":"J. Biochem. Mol. Biol."},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M604416200"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2008.08.012"},{"key":"B45","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.jacc.2008.08.069","volume":"53","author":"Nagayama","year":"2009","journal-title":"J. Am. Coll. Cardiol."},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2193"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.162100799"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M204491200"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.107.157677"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M603416200"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M706360200"},{"key":"B52","doi-asserted-by":"crossref","first-page":"5244","DOI":"10.1128\/MCB.17.9.5244","volume":"17","author":"Gudi","year":"1997","journal-title":"Mol. Cell. Biol."},{"key":"B53","doi-asserted-by":"crossref","first-page":"R1134","DOI":"10.1152\/ajpregu.00246.2004","volume":"288","author":"Gross","year":"2005","journal-title":"Am. J. Physiol. Regul. Integr. Comp. Physiol."},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.220414397"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.595231"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.275.18.13571"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000152262.22968.72"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jci.org\/articles\/view\/35620\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:09:52Z","timestamp":1691068192000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/35620"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,1,5]]},"references-count":57,"URL":"https:\/\/doi.org\/10.1172\/jci35620","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.1145244.602405","asserted-by":"object"},{"id-type":"doi","id":"10.3410\/f.1145244.604968","asserted-by":"object"}]},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2009,1,5]]}}}