{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T22:01:00Z","timestamp":1792706460196,"version":"4.5.0"},"reference-count":52,"publisher":"American Society for Clinical Investigation","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"published-print":{"date-parts":[[2010,11,1]]},"DOI":"10.1172\/jci43025","type":"journal-article","created":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T13:03:48Z","timestamp":1288616628000},"page":"4040-4054","source":"Crossref","is-referenced-by-count":322,"title":["Epithelial Notch signaling regulates interstitial fibrosis development in the kidneys of mice and humans"],"prefix":"10.1172","volume":"120","author":[{"given":"Bernhard","family":"Bielesz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasemin","family":"Sirin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Han","family":"Si","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thiruvur","family":"Niranjan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antje","family":"Gruenwald","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seonho","family":"Ahn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Kato","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Pullman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manfred","family":"Gessler","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker H.","family":"Haase","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katalin","family":"Susztak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","first-page":"918","volume":"53","year":"2004","journal-title":"MMWR Morb Mortal Wkly Rep."},{"key":"B2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0272-6386(12)80312-X","volume":"20","author":"Nath","year":"1992","journal-title":"Am J Kidney Dis."},{"key":"B3","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1159\/000025906","volume":"22","author":"Kriz","year":"1999","journal-title":"Kidney Blood Press Res."},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2009.314"},{"key":"B5","doi-asserted-by":"crossref","first-page":"1776","DOI":"10.1172\/JCI200320530","volume":"112","author":"Kalluri","year":"2003","journal-title":"J Clin Invest."},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7601421"},{"key":"B7","first-page":"3810","volume":"117","author":"Higgins","year":"2007","journal-title":"J Clin Invest."},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2008.01.014"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2008.080433"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/S1567-133X(03)00114-5"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1523-1755.2005.00627.x"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007040453"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1038\/nm1731"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2007050596"},{"key":"B15","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.bbadis.2007.09.005","volume":"1782","author":"Walsh","year":"2008","journal-title":"Biochim Biophys Acta."},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1159\/000209207"},{"key":"B17","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1097\/01.ASN.0000017905.77985.4A","volume":"13","author":"Morrissey","year":"2002","journal-title":"J Am Soc Nephrol."},{"key":"B18","doi-asserted-by":"crossref","first-page":"F431","DOI":"10.1152\/ajprenal.0009.2001","volume":"282","author":"Surendran","year":"2002","journal-title":"Am J Physiol Renal Physiol."},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/nm1217"},{"key":"B20","doi-asserted-by":"crossref","first-page":"3291","DOI":"10.1242\/dev.121.10.3291","volume":"121","author":"Oka","year":"1995","journal-title":"Development."},{"key":"B21","doi-asserted-by":"crossref","first-page":"4133","DOI":"10.1242\/dev.124.20.4133","volume":"124","author":"Kato","year":"1997","journal-title":"Development."},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1865"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0505690102"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-01-0355"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39675"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1101\/gad.276304"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200710067"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq006"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6793-4-10"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.111614398"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200612129"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/nm888"},{"key":"B33","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1172\/JCI0215518","volume":"110","author":"Iwano","year":"2002","journal-title":"J Clin Invest."},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200601018"},{"key":"B35","unstructured":"Nephromine. Nephromine Research Web site. http:\/\/www.nephromine.org . Accessed September 1, 2010."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.090517"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-0974"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2009.05.016"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1172\/JCI30070"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0709663105"},{"key":"B41","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1172\/JCI200319270","volume":"112","author":"Sato","year":"2003","journal-title":"J Clin Invest."},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1038\/sj.emboj.7600069"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2005.09.010"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0802047105"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0903458106"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2009.498"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2144"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2853"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0020045"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32086"},{"key":"B51","doi-asserted-by":"crossref","first-page":"1240","DOI":"10.1038\/ki.2008.74","volume":"73","author":"Kobayashi","year":"2008","journal-title":"Kidney Int."},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1002\/dvdy.21000"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jci.org\/articles\/view\/43025\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:18:43Z","timestamp":1691083123000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/43025"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11,1]]},"references-count":52,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2010,11,1]]}},"URL":"https:\/\/doi.org\/10.1172\/jci43025","relation":{},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2010,11,1]]}}}