{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T20:57:26Z","timestamp":1791406646188,"version":"4.3.3"},"reference-count":119,"publisher":"American Society for Clinical Investigation","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J. Clin. Invest."],"published-print":{"date-parts":[[2011,6,1]]},"DOI":"10.1172\/jci57132","type":"journal-article","created":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T08:00:46Z","timestamp":1306915246000},"page":"2111-2117","source":"Crossref","is-referenced-by-count":2066,"title":["Inflammatory links between obesity and metabolic disease"],"prefix":"10.1172","volume":"121","author":[{"given":"Carey N.","family":"Lumeng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan R.","family":"Saltiel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05485"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00329.2010"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-2182"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI42845"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1042\/BST0350466"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.201"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1471"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/nature06757"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1038\/nature06758"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117936"},{"key":"B11","doi-asserted-by":"crossref","first-page":"1595","DOI":"10.1161\/01.ATV.20.6.1595","volume":"20","author":"Hotta","year":"2000","journal-title":"Arterioscler. Thromb Vasc Biol."},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.2337\/db08-0872"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2002"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.90885.2008"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.2337\/db09-0016"},{"key":"B16","doi-asserted-by":"crossref","first-page":"16","DOI":"10.2337\/db06-1076","volume":"6","author":"Lumeng","year":"2007","journal-title":"Diabetes."},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.04.003"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2004.09.015"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1402"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2010.103"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2009-0925"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1172\/JCI29881"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.08.015"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-011110-130138"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/nature05894"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.04.002"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1126\/science.1201475"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/nature08636"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2001"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.07.041"},{"key":"B31","doi-asserted-by":"crossref","first-page":"1821","DOI":"10.1172\/JCI200319451","volume":"112","author":"Xu","year":"2003","journal-title":"J Clin Invest."},{"key":"B32","doi-asserted-by":"crossref","first-page":"1796","DOI":"10.1172\/JCI200319246","volume":"112","author":"Weisberg","year":"2003","journal-title":"J Clin Invest."},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1042\/BST0360340"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2009.12.010"},{"key":"B35","doi-asserted-by":"crossref","first-page":"851","DOI":"10.1172\/JCI200215318","volume":"110","author":"Maedler","year":"2002","journal-title":"J Clin Invest."},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.2337\/db06-1650"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31021"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.2337\/db10-0113"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009997"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2009.133"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.2337\/db07-0767"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.2337\/db06-0911"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1126\/science.1103160"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1964"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/nm.1994"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.109.198614"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0904944106"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20826"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21221"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2009.03.008"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.2337\/db09-1403"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118504"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00307.2009"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.2337\/db08-1261"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070075"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1038\/ng.686"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-0336"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1172\/JCI43378"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1172\/JCI36714"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.07.043"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2009.08.013"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.12.004"},{"key":"B63","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1093\/cvr\/cvp073","volume":"82","author":"Kang","year":"2009","journal-title":"Cardiovasc Res."},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.173021"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1006875108"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00301.2010"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1016\/j.yfrne.2009.10.002"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000465"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1111\/j.1467-789X.2010.00735.x"},{"key":"B70","doi-asserted-by":"crossref","first-page":"176","DOI":"10.7326\/0003-4819-133-3-200008010-00008","volume":"133","author":"Forsen","year":"2000","journal-title":"Ann Intern Med."},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e31816339c6"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1177\/1933719108329095"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2010.215"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1210\/en.2010-1332"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1097\/MED.0b013e328013da8e"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.2337\/db08-1266"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.2337\/db10-0367"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.12.008"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1038\/nature09491"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2006.02.010"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0b013e32832fa5c4"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1172\/JCI28898"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2009.09.006"},{"key":"B84","doi-asserted-by":"crossref","first-page":"823486","DOI":"10.1155\/2010\/823486","volume":"2010","author":"Poulain-Godefroy","year":"2010","journal-title":"Mediators Inflamm."},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-141929"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1126\/science.1179721"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pathol.4.110807.092239"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1126\/science.1184003"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1831"},{"key":"B90","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1038\/nm.2279","volume":"17","author":"Vandanmagsar","year":"2011","journal-title":"Nat Med."},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0012537"},{"key":"B92","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1038\/nm1185","volume":"11","author":"Arkan","year":"2005","journal-title":"Nat Med."},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1038\/nm1166"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1126\/science.1061620"},{"key":"B95","doi-asserted-by":"crossref","first-page":"346","DOI":"10.7326\/0003-4819-152-6-201003160-00004","volume":"152","author":"Goldfine","year":"2010","journal-title":"Ann Intern Med."},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2010.12.008"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.06.046"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00776.2009"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2329"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1097\/MOL.0b013e3283373b66"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.01.002"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2277"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2011.02.010"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-151340"},{"key":"B105","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1038\/nature01137","volume":"420","author":"Hirosumi","year":"2002","journal-title":"Nature."},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0603509103"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1001796107"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2007.09.011"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003151"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.034"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1126\/science.1128294"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.01.001"},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.224766"},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1111\/j.1752-8062.2008.00026.x"},{"key":"B115","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31561"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa065213"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1159\/000088261"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2010-1170"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1000021"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.jci.org\/articles\/view\/57132\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:09:53Z","timestamp":1691068193000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.jci.org\/articles\/view\/57132"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6,1]]},"references-count":119,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6,1]]}},"URL":"https:\/\/doi.org\/10.1172\/jci57132","relation":{},"ISSN":["0021-9738"],"issn-type":[{"value":"0021-9738","type":"print"}],"subject":[],"published":{"date-parts":[[2011,6,1]]}}}