{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T17:06:34Z","timestamp":1791219994046,"version":"4.1.0"},"reference-count":49,"publisher":"American Society for Clinical Investigation","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,5,3]]},"DOI":"10.1172\/jci85782","type":"journal-article","created":{"date-parts":[[2016,5,2]],"date-time":"2016-05-02T22:00:33Z","timestamp":1462226433000},"page":"2151-2166","source":"Crossref","is-referenced-by-count":344,"title":["Alternatively activated macrophages determine repair of the infarcted adult murine heart"],"prefix":"10.1172","volume":"126","author":[{"given":"Manabu","family":"Shiraishi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasunori","family":"Shintani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuke","family":"Shintani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hidekazu","family":"Ishida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rie","family":"Saba","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Yamaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideo","family":"Adachi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenta","family":"Yashiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ken","family":"Suzuki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2009.199"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2013.11.015"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1126\/science.1200708"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.05.007"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1501441112"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009060615"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.303567"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.11.019"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070885"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.112.248732"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/nm.3816"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.07.057"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.300502"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-60327-360-2_13"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvu059"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/nature11930"},{"key":"B17","unstructured":"Nichols M et al European Cardiovascular Disease Statistics 2012 Brussels, Belgium: European Heart Network, Brussels, European Society of Cardiology, Sophia Antipolis; 2012 https:\/\/www.escardio.org\/static_file\/Escardio\/Press-media\/press-releases\/2013\/EU-cardiovascular-disease-statistics-2012.pdf April 4, 2016"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1015623108"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.303895"},{"issue":"1 suppl","key":"B20","first-page":"I94","article-title":"Ex vivo activated human macrophages improve healing, remodeling, and function of the infarcted heart","volume":"114","author":"Leor","year":"2006","journal-title":"Circulation"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60134-8"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1015623108"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1126\/science.1204351"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-02-408252"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-06-436212"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1172\/JCI59643"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2005.06.003"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1101841108"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1210\/me.2014-1092"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2015.01.003"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2013.04.023"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.188243"},{"issue":"12 suppl 1","key":"B33","doi-asserted-by":"crossref","first-page":"I308","DOI":"10.1161\/hc37t1.094871","article-title":"Overexpression of interleukin-1 receptor antagonist provides cardioprotection against ischemia-reperfusion injury associated with reduction in apoptosis","volume":"104","author":"Suzuki","year":"2001","journal-title":"Circulation"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2012.17"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2010.120"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2013.87"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1161\/hh1001.090842"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2009.06.015"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1038\/nature13807"},{"issue":"2","key":"B40","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1177\/039463201102400204","article-title":"Allergic inflammation: role of cytokines with special emphasis on IL-4","volume":"24","author":"Saggini","year":"2011","journal-title":"Int J Immunopathol Pharmacol"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvn120"},{"key":"B42","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.2119\/molmed.2012.00131","article-title":"MyD88 signaling pathway is involved in renal fibrosis by favoring a TH2 immune response and activating alternative M2 macrophages","volume":"18","author":"Braga","year":"2012","journal-title":"Mol Med"},{"issue":"12","key":"B43","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1016\/0959-8049(93)90108-R","article-title":"Recombinant human interleukin-4 (rhu IL-4) administered by the intravenous and subcutaneous routes in patients with advanced cancer \u2014 a phase I toxicity study and pharmacokinetic analysis","volume":"29A","author":"Prendiville","year":"1993","journal-title":"Eur J Cancer"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e3181f5dfc5"},{"issue":"10","key":"B45","doi-asserted-by":"crossref","first-page":"1864","DOI":"10.1038\/mt.2014.110","article-title":"Epicardial placement of mesenchymal stromal cell-sheets for the treatment of ischemic cardiomyopathy; in vivo proof-of-concept study","volume":"22","author":"Tano","year":"2014","journal-title":"Mol Ther"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1219243110"},{"key":"B47","doi-asserted-by":"crossref","DOI":"10.1002\/0471142735.im1401s83","article-title":"The isolation and characterization of murine macrophages","volume":"Chapter 14","author":"Zhang","year":"2008","journal-title":"Curr Protoc Immunol"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2012.09.081"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/S0008-6363(00)00170-X"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/85782\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:53:17Z","timestamp":1691085197000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/85782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5,3]]},"references-count":49,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2016,6,1]]}},"alternative-id":["10.1172\/JCI85782"],"URL":"https:\/\/doi.org\/10.1172\/jci85782","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,5,3]]}}}