{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T08:12:54Z","timestamp":1776240774856,"version":"3.50.1"},"reference-count":58,"publisher":"American Society for Clinical Investigation","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2016,9,12]]},"DOI":"10.1172\/jci88546","type":"journal-article","created":{"date-parts":[[2016,9,11]],"date-time":"2016-09-11T22:00:27Z","timestamp":1473631227000},"page":"3942-3960","source":"Crossref","is-referenced-by-count":23,"title":["Aging promotes acquisition of naive-like CD8+ memory T cell traits and enhanced functionalities"],"prefix":"10.1172","volume":"126","author":[{"given":"Jens","family":"Eberlein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bennett","family":"Davenport","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tom","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco","family":"Victorino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelsey","family":"Haist","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Jhun","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anis","family":"Karimpour-Fard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Hunter","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ross","family":"Kedl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric T.","family":"Clambey","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Homann","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2007.08.007"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/nri2251"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.10.008"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2010.00926.x"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.coi.2011.05.002"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/nri2959"},{"key":"B7"},{"key":"B8","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2013.00271","article-title":"Human T cell aging and the impact of persistent viral infections","volume":"4","author":"F\u00fcl\u00f6p","year":"2013","journal-title":"Front Immunol"},{"key":"B9","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2013.00121","article-title":"T cell aging: a review of the transcriptional changes determined from genome-wide analysis","volume":"4","author":"Chen","year":"2013","journal-title":"Front Immunol"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1401174"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/90950"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/ni889"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20070322"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20050137"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2007.09.006"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1101579"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005219"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1172\/JCI40645"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1000041"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.03.020"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1003054"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1101098"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.173.8.4779"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.177.2.831"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/nm1492"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2009.06.015"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1126\/science.1208421"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3322"},{"issue":"1","key":"B29","doi-asserted-by":"crossref","first-page":"236","DOI":"10.1002\/1521-4141(200001)30:1<236::AID-IMMU236>3.0.CO;2-X","article-title":"Memory CD8 T lymphocytes express inhibitory MHC-specific Ly49 receptors","volume":"30","author":"Coles","year":"2000","journal-title":"Eur J Immunol"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-032712-095954"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(02)01139-X"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.04.008"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.22.012703.104702"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2079"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0060420"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.174.6.3757"},{"key":"B37","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms9306","article-title":"Functional classification of memory CD8(+) T cells by CX3CR1 expression","volume":"6","author":"B\u00f6ttcher","year":"2015","journal-title":"Nat Commun"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.171.1.27"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-032414-112014"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.10.6704"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2009.05126.x"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1002145"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005199"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.11.4106-4114.2000"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20081829"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1038\/nri3173"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0501437102"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.175.9.5895"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2446"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20131271"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12132"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.05.017"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.05.009"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2013.07.003"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.06.014"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2008.02.020"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2014.10.026"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2012.01.002"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/88546\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:09:54Z","timestamp":1691082594000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/88546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,9,12]]},"references-count":58,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,10,3]]}},"alternative-id":["10.1172\/JCI88546"],"URL":"https:\/\/doi.org\/10.1172\/jci88546","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,9,12]]}}}