{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T03:30:02Z","timestamp":1790998202481,"version":"4.1.0"},"reference-count":50,"publisher":"American Society for Clinical Investigation","issue":"11","funder":[{"DOI":"10.13039\/501100000024","name":"Canadian Institutes for Health Research","doi-asserted-by":"crossref","award":["MOP-142281"],"award-info":[{"award-number":["MOP-142281"]}],"id":[{"id":"10.13039\/501100000024","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Canadian Cancer Society","award":["703811"],"award-info":[{"award-number":["703811"]}]},{"name":"National Centre for Research and Development, INNOTECH Program","award":["INNOTECH-K1\/HI1\/16\/157483\/NCBR\/12"],"award-info":[{"award-number":["INNOTECH-K1\/HI1\/16\/157483\/NCBR\/12"]}]},{"name":"Qu\u00e9bec\/Wallonie-Bruxelles International","award":["Qu\u00e9bec\/Wallonie-Bruxelles International"],"award-info":[{"award-number":["Qu\u00e9bec\/Wallonie-Bruxelles International"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10,16]]},"DOI":"10.1172\/jci91258","type":"journal-article","created":{"date-parts":[[2017,10,15]],"date-time":"2017-10-15T22:00:37Z","timestamp":1508104837000},"page":"4179-4192","source":"Crossref","is-referenced-by-count":70,"title":["MNK1\/2 inhibition limits oncogenicity and metastasis of KIT-mutant melanoma"],"prefix":"10.1172","volume":"127","author":[{"given":"Yao","family":"Zhan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christophe","family":"Goncalves","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomasz","family":"Rzymski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agnieszka","family":"Dreas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliza","family":"\u017by\u0142kiewicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maciej","family":"Mikulski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krzysztof","family":"Brz\u00f3zka","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aniela","family":"Golas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meng","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bonnie","family":"Huor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianyu","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sabrina Daniela","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose","family":"Torres","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutian","family":"Cai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan","family":"Topisirovic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krikor","family":"Bijian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moulay A.","family":"Alaoui-Jamali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidong","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabrice","family":"Journe","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghanem E.","family":"Ghanem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"Wilson H.","family":"Miller","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sonia V.","family":"del Rinc\u00f3n","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.10.650"},{"issue":"suppl 1","key":"B2","doi-asserted-by":"crossref","first-page":"S6","DOI":"10.1097\/SAP.0000000000000731","article-title":"Clinical patterns of melanoma in Asians: 11-year experience in a tertiary referral center","volume":"77","author":"Chan","year":"2016","journal-title":"Ann Plast Surg"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-2346"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2006.06.2984"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2011.746"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.33.9275"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2015.05.044"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2012.562"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1111\/pcmr.12107"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.01.042"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2014.552"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2015.450"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.8.1921"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.8.1909"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1005320107"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1008136107"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2014.146"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-04-2677"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1604407"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.453"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-3112"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.8.15.8960"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21834"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.47.7836"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-09-0459"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.4662"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-04-2245"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.3109\/10409238.2011.578612"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-642-54490-3_2"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.6904"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1038\/nature10912"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1068"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-013-1474-x"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.3357"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1159\/000111092"},{"issue":"2","key":"B36","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/leu.2010.215","article-title":"Management of adverse events associated with tyrosine kinase inhibitors in the treatment of chronic myeloid leukemia","volume":"25","author":"Jabbour","year":"2011","journal-title":"Leukemia"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.10796"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-16-0172"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1172\/JCI85183"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.4161\/cbt.10.7.12965"},{"issue":"9","key":"B41","first-page":"3614","article-title":"Levels of cyclin D1 and D3 in malignant melanoma: deregulated cyclin D3 expression is associated with poor clinical outcome in superficial melanoma","volume":"6","author":"Fl\u00f8renes","year":"2000","journal-title":"Clin Cancer Res"},{"issue":"3","key":"B42","doi-asserted-by":"crossref","first-page":"692","DOI":"10.1158\/0008-5472.692.65.3","article-title":"The low molecular weight cyclin E isoforms augment angiogenesis and metastasis of human melanoma cells in vivo","volume":"65","author":"Bales","year":"2005","journal-title":"Cancer Res"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25766"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.30259"},{"issue":"11","key":"B45","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a012252","article-title":"Regulation of mRNA translation by signaling pathways","volume":"4","author":"Roux","year":"2012","journal-title":"Cold Spring Harb Perspect Biol"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-15-0885"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2015.11"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-02-698704"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2016.01.024"},{"issue":"87","key":"B50","doi-asserted-by":"crossref","DOI":"10.3791\/51455","article-title":"Polysome fractionation and analysis of mammalian translatomes on a genome-wide scale","author":"Gandin","year":"2014","journal-title":"J Vis Exp"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/91258\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,4]],"date-time":"2022-08-04T17:12:33Z","timestamp":1659633153000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/91258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10,16]]},"references-count":50,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2017,11,1]]}},"alternative-id":["10.1172\/JCI91258"],"URL":"https:\/\/doi.org\/10.1172\/jci91258","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10,16]]}}}