{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T18:46:43Z","timestamp":1790275603054,"version":"4.1.0"},"reference-count":68,"publisher":"American Society for Clinical Investigation","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,4,24]]},"DOI":"10.1172\/jci91363","type":"journal-article","created":{"date-parts":[[2017,4,23]],"date-time":"2017-04-23T22:00:39Z","timestamp":1492984839000},"page":"2206-2221","source":"Crossref","is-referenced-by-count":80,"title":["The U2AF1S34F mutation induces lineage-specific splicing alterations in myelodysplastic syndromes"],"prefix":"10.1172","volume":"127","author":[{"given":"Bon Ham","family":"Yip","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5468-460X","authenticated-orcid":false,"given":"Violetta","family":"Steeples","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8085-0731","authenticated-orcid":false,"given":"Emmanouela","family":"Repapi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard N.","family":"Armstrong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miriam","family":"Llorian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swagata","family":"Roy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jacqueline","family":"Shaw","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4724-1720","authenticated-orcid":false,"given":"Hamid","family":"Dolatshad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Verma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0908-770X","authenticated-orcid":false,"given":"Matthias","family":"Bartenstein","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3931-0914","authenticated-orcid":false,"given":"Paresh","family":"Vyas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas C.P.","family":"Cross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1460-1611","authenticated-orcid":false,"given":"Luca","family":"Malcovati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6984-8817","authenticated-orcid":false,"given":"Mario","family":"Cazzola","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eva","family":"Hellstr\u00f6m-Lindberg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7778-5374","authenticated-orcid":false,"given":"Seishi","family":"Ogawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher W.J.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6122-0221","authenticated-orcid":false,"given":"Andrea","family":"Pellagatti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4330-2928","authenticated-orcid":false,"given":"Jacqueline","family":"Boultwood","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-09-381665"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-03-420489"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12515"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-03-209262"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-08-518886"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/nature10496"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1103283"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-12-399774"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-09-377275"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-09-377994"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-12-400994"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2016.149"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2015.04.006"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1038\/ng.259"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(88)90509-0"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/45590"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/ng.1031"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087361"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1002\/wrna.1222"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-015-4305-2"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.23541"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1101\/gad.267104.115"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1101\/gr.181016.114"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-01-480970"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2014.303"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2015.04.008"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1311055110"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12217"},{"issue":"2","key":"B29","first-page":"161","article-title":"Leukocyte CD11\/CD18 integrins: biological and clinical relevance","volume":"80","author":"Mazzone","year":"1995","journal-title":"Haematologica"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1002\/stem.5530130208"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1419161111"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2016.04.011"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2015.06.002"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2012.075325"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-03-0947"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2008.01950.x"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbior.2016.08.001"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.15252\/embr.201541116"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv194"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0408918102"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1186\/1756-8935-3-8"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.01.034"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4644(199704)65:1<107::AID-JCB11>3.0.CO;2-H"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.466144"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2009.26"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1388"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi343"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.4161\/15384101.2014.973310"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.2741\/3678"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.20.9.3157-3167.2000"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2933"},{"issue":"2","key":"B52","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1038\/nrd3625","article-title":"RNA therapeutics: beyond RNA interference and antisense oligonucleotides","volume":"11","author":"Kole","year":"2012","journal-title":"Nat Rev Drug Discov"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw533"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts635"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts196"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp352"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btt656"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt214"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp616"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1621"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1038\/nmeth.1528"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2010-11-2-r14"},{"key":"B63","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2105-10-2","article-title":"GenomeGraphs: integrated genomic data visualization with R","volume":"10","author":"Durinck","year":"2009","journal-title":"BMC Bioinformatics"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bti525"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1003118"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1101\/gr.849004"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1089\/1066527041410418"},{"key":"B68","article-title":"The impact of sequence length and number of sequences on promoter prediction performance","volume":"16 Suppl 19","author":"Carvalho","year":"2015","journal-title":"BMC Bioinformatics"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/91363\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:11:37Z","timestamp":1691082697000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/91363"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,24]]},"references-count":68,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2017,6,1]]}},"alternative-id":["10.1172\/JCI91363"],"URL":"https:\/\/doi.org\/10.1172\/jci91363","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,24]]}}}