{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,2]],"date-time":"2026-02-02T14:36:48Z","timestamp":1770043008480,"version":"3.49.0"},"reference-count":54,"publisher":"American Society for Clinical Investigation","issue":"11","funder":[{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["NSFC: 81671336"],"award-info":[{"award-number":["NSFC: 81671336"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["81271481"],"award-info":[{"award-number":["81271481"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["81171266"],"award-info":[{"award-number":["81171266"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["81500976"],"award-info":[{"award-number":["81500976"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["NSFS: 06ZR14147"],"award-info":[{"award-number":["NSFS: 06ZR14147"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["10PJ1408800"],"award-info":[{"award-number":["10PJ1408800"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["11140900400"],"award-info":[{"award-number":["11140900400"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100005326","name":"Yale University","doi-asserted-by":"crossref","award":["RO1 AI042310"],"award-info":[{"award-number":["RO1 AI042310"]}],"id":[{"id":"10.13039\/100005326","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100005326","name":"Yale University","doi-asserted-by":"crossref","award":["AR049610"],"award-info":[{"award-number":["AR049610"]}],"id":[{"id":"10.13039\/100005326","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100005326","name":"Yale University","doi-asserted-by":"crossref","award":["HL128069"],"award-info":[{"award-number":["HL128069"]}],"id":[{"id":"10.13039\/100005326","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100004921","name":"Shanghai Jiao Tong University","doi-asserted-by":"crossref","award":["14YF1413500"],"award-info":[{"award-number":["14YF1413500"]}],"id":[{"id":"10.13039\/501100004921","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100005616","name":"Memorial University of Newfoundland","doi-asserted-by":"crossref","award":["RDC 5404.1980.102,NSERC: RGPIN-2017-04542,CIHR Project Grant: PJT-156116"],"award-info":[{"award-number":["RDC 5404.1980.102,NSERC: RGPIN-2017-04542,CIHR Project Grant: PJT-156116"]}],"id":[{"id":"10.13039\/501100005616","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,8]]},"DOI":"10.1172\/jci93090","type":"journal-article","created":{"date-parts":[[2018,10,7]],"date-time":"2018-10-07T22:00:46Z","timestamp":1538949646000},"page":"4997-5007","source":"Crossref","is-referenced-by-count":40,"title":["Macrophage migration inhibitory factor mediates metabolic dysfunction induced by atypical antipsychotic therapy"],"prefix":"10.1172","volume":"128","author":[{"given":"Donghong","family":"Cui","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanmin","family":"Peng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengfang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zezhi","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yousong","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yadan","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengjuan","family":"Xing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jia","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Grace E.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin N.","family":"Su","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinjie","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Meiti","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenhua","family":"Ding","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Piecychna","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Leng","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiru","family":"Hirasawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kaida","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence","family":"Young","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yifeng","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dake","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Bucala","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"232","published-online":{"date-parts":[[2018,10,8]]},"reference":[{"issue":"5","key":"B1","first-page":"617","article-title":"Adverse effects of antipsychotic medications","volume":"81","author":"Muench","year":"2010","journal-title":"Am Fam Physician"},{"issue":"Suppl 1","key":"B2","first-page":"1","article-title":"Second-generation (atypical) antipsychotics and metabolic effects: a comprehensive literature review","volume":"19","author":"Newcomer","year":"2005","journal-title":"CNS Drugs"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-3421"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0022662"},{"issue":"1\u20133","key":"B5","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.schres.2008.06.006","article-title":"Insulin resistance following continuous, chronic olanzapine treatment: an animal model","volume":"104","author":"Chintoh","year":"2008","journal-title":"Schizophr Res"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-008-1415-1"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001948"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.8.5399"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.199166"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.2337\/diacare.29.02.06.dc05-1474"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2004-0436"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1038\/ijo.2009.106"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1038\/nature06504"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1002\/art.30624"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-005-2224-4"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1177\/026988110201600402"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2010.33"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.54.3.862"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.6.1055"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.108.137240"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1533295100"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2008.02.011"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(03)00481-9"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)63797-2"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00797-10"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1172\/JCI10583"},{"key":"B27","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/647476","article-title":"Risk of mortality (including sudden cardiac death) and major cardiovascular events in users of olanzapine and other antipsychotics: a study with the general practice research database","volume":"2013","author":"Jones","year":"2013","journal-title":"Cardiovasc Psychiatry Neurol"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.325.7358.243"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1677\/JOE-09-0342"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2014.01.018"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31516"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-002-0896-4"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1283150"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1038\/377068a0"},{"key":"B35","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2015.00308","article-title":"Role of macrophage migration inhibitory factor in obesity, insulin resistance, type 2 diabetes, and associated hepatic co-morbidities: a comprehensive review of human and rodent studies","volume":"6","author":"Morrison","year":"2015","journal-title":"Front Immunol"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1210\/en.2004-0924"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ijo.0802942"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.nutr.27.061406.093734"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2013.08.002"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.012511599"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20052398"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1301128110"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0113369"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gene.6363867"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1038\/oby.2006.6"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-006-0433-0"},{"key":"B47","article-title":"A murine model of atypical antipsychotic-induced weight gain and metabolic dysregulation","volume":"Chapter 9","author":"Coccurello","year":"2010","journal-title":"Curr Protoc Neurosci"},{"key":"B48","article-title":"Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway","volume":"4","author":"Gil","year":"2013","journal-title":"Nat Commun"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1002\/jmri.21090"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1038\/nm0397-320"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1021\/bi00251a025"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00238.2012"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2012.03.005"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1172\/JCI39738"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/93090\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:12:15Z","timestamp":1691082735000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/93090"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,8]]},"references-count":54,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2018,9,24]]},"published-print":{"date-parts":[[2018,9,24]]}},"alternative-id":["10.1172\/JCI93090"],"URL":"https:\/\/doi.org\/10.1172\/jci93090","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,8]]}}}