{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:39:43Z","timestamp":1792190383571,"version":"4.4.0"},"reference-count":17,"publisher":"American Society for Clinical Investigation","issue":"10","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,9,18]]},"DOI":"10.1172\/jci93094","type":"journal-article","created":{"date-parts":[[2017,9,17]],"date-time":"2017-09-17T18:00:30Z","timestamp":1505671230000},"page":"3861-3865","source":"Crossref","is-referenced-by-count":68,"title":["Increased intracellular proteolysis reduces disease severity in an ER stress\u2013associated dwarfism"],"prefix":"10.1172","volume":"127","author":[{"given":"Lorna A.","family":"Mullan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ewa J.","family":"Mularczyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Louise H.","family":"Kung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mitra","family":"Forouhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan M.A.","family":"Wragg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Royston","family":"Goodacre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John F.","family":"Bateman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eileithyia","family":"Swanton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael D.","family":"Briggs","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raymond P.","family":"Boot-Handford","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/ng0993-79"},{"issue":"2","key":"B2","first-page":"169","article-title":"Amino acid substitutions of conserved residues in the carboxyl-terminal domain of the alpha 1(X) chain of type X collagen occur in two unrelated families with metaphyseal chondrodysplasia type Schmid","volume":"54","author":"Wallis","year":"1994","journal-title":"Am J Hum Genet"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/humu.20183"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M410758200"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0050044"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1000691"},{"key":"B7","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1111\/j.1528-1167.2012.03712.x","article-title":"Why are antiepileptic drugs used for nonepileptic conditions?","volume":"53 Suppl 7","author":"Bialer","year":"2012","journal-title":"Epilepsia"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200504035"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-010-0651-y"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1126\/science.1190354"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1126\/science.1128294"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1354.070"},{"issue":"2 Pt 1","key":"B13","doi-asserted-by":"crossref","first-page":"C599","DOI":"10.1152\/ajpcell.1998.275.2.C599","article-title":"Activation of DeltaF508 CFTR in an epithelial monolayer","volume":"275","author":"Beb\u00f6k","year":"1998","journal-title":"Am J Physiol"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.201889"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2009.01.021"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.E08-11-1092"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.4103\/0976-0105.177703"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/93094\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:12:15Z","timestamp":1691068335000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/93094"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,9,18]]},"references-count":17,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10,2]]}},"alternative-id":["10.1172\/JCI93094"],"URL":"https:\/\/doi.org\/10.1172\/jci93094","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,9,18]]}}}