{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T05:54:43Z","timestamp":1787637283020,"version":"build-2736575974"},"reference-count":31,"publisher":"American Society for Clinical Investigation","issue":"12","funder":[{"name":"NIAID\/NIH","award":["U19AI109711"],"award-info":[{"award-number":["U19AI109711"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,11,6]]},"DOI":"10.1172\/jci96185","type":"journal-article","created":{"date-parts":[[2017,11,5]],"date-time":"2017-11-05T23:00:28Z","timestamp":1509922828000},"page":"4437-4448","source":"Crossref","is-referenced-by-count":38,"title":["siRNA rescues nonhuman primates from advanced Marburg and Ravn virus disease"],"prefix":"10.1172","volume":"127","author":[{"given":"Emily P.","family":"Thi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad E.","family":"Mire","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy C.H.","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan B.","family":"Geisbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Raul","family":"Ursic-Bedoya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krystle N.","family":"Agans","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie","family":"Robbins","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel J.","family":"Deer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert W.","family":"Cross","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Kondratowicz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Karla A.","family":"Fenton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"MacLachlan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas W.","family":"Geisbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2015.01.014"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00069-06"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S106625"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60357-1"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1038\/nature14442"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1038\/nmicrobiol.2016.142"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1001997"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit465"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3009706"},{"key":"B10","doi-asserted-by":"crossref","first-page":"S372","DOI":"10.1086\/520608","article-title":"Marburg virus Angola infection of rhesus macaques: pathogenesis and treatment with recombinant nematode anticoagulant protein c2","volume":"196 Suppl 2","author":"Geisbert","year":"2007","journal-title":"J Infect Dis"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1404505"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(14)70034-9"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(06)68546-2"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.661"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1200409109"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2202"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/nature13027"},{"issue":"10","key":"B18","first-page":"457","article-title":"A hitherto unknown infectious disease contracted from monkeys. \u201cMarburg-virus\u201d disease","volume":"13","author":"Martini","year":"1968","journal-title":"Ger Med Mon"},{"issue":"8276","key":"B19","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/S0140-6736(82)91871-2","article-title":"Marburg-virus disease in Kenya","volume":"1","author":"Smith","year":"1982","journal-title":"Lancet"},{"issue":"384","key":"B20","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.aai8711","article-title":"Therapeutic treatment of Marburg and Ravn virus infection in nonhuman primates with a human monoclonal antibody","volume":"9","author":"Mire","year":"2017","journal-title":"Sci Transl Med"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa051465"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix201"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1038\/35078107"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1038\/nbt831"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkg147"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki312"},{"key":"B27","doi-asserted-by":"crossref","first-page":"S258","DOI":"10.1093\/infdis\/jiv182","article-title":"Comparison of the pathogenesis of the Angola and Ravn strains of Marburg virus in the outbred guinea pig model","volume":"212 Suppl 2","author":"Cross","year":"2015","journal-title":"J Infect Dis"},{"key":"B28","article-title":"Transdermal delivery of siRNA through microneedle array","volume":"6","author":"Deng","year":"2016","journal-title":"Sci Rep"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1021\/ja505986a"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.09.049"},{"key":"B31","doi-asserted-by":"crossref","first-page":"S1021","DOI":"10.1093\/infdis\/jir339","article-title":"Pathogenesis of Marburg hemorrhagic fever in cynomolgus macaques","volume":"204 Suppl 3","author":"Hensley","year":"2011","journal-title":"J Infect Dis"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/96185\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T17:13:44Z","timestamp":1691082824000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/96185"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,11,6]]},"references-count":31,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2017,10,23]]}},"alternative-id":["10.1172\/JCI96185"],"URL":"https:\/\/doi.org\/10.1172\/jci96185","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,11,6]]}}}