{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T04:12:06Z","timestamp":1791000726442,"version":"4.1.0"},"reference-count":70,"publisher":"American Society for Clinical Investigation","issue":"12","funder":[{"name":"NIH","award":["HL072166"],"award-info":[{"award-number":["HL072166"]}]},{"name":"NIH","award":["HL085629"],"award-info":[{"award-number":["HL085629"]}]},{"name":"NIH","award":["HL131667"],"award-info":[{"award-number":["HL131667"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,10,22]]},"DOI":"10.1172\/jci98287","type":"journal-article","created":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T16:03:42Z","timestamp":1536681822000},"page":"5294-5306","source":"Crossref","is-referenced-by-count":37,"title":["Inadequate ubiquitination-proteasome coupling contributes to myocardial ischemia-reperfusion injury"],"prefix":"10.1172","volume":"128","author":[{"given":"Chengjun","family":"Hu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yihao","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongxin","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5705-5446","authenticated-orcid":false,"given":"Bo","family":"Pan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erin M.","family":"Terpstra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Penglong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmin","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9954-095X","authenticated-orcid":false,"given":"Faqian","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinbao","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9267-1343","authenticated-orcid":false,"given":"Xuejun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"232","published-online":{"date-parts":[[2018,10,22]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.04.023"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000252342.61447.a2"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1126\/science.279.5348.242"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.112.270207"},{"key":"B5","doi-asserted-by":"crossref","DOI":"10.1186\/s13059-015-0861-4","article-title":"FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy","volume":"17","author":"Al-Yacoub","year":"2016","journal-title":"Genome Biol"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1172\/JCI66339"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1172\/JCI74994"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.09.004"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611726104"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1172\/JCI32827"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.109.194928"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000259559.48597.32"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31757"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1172\/JCI93445"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.113.001971"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1172\/JCI45709"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4011"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1522332112"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3531"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2012.09.012"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.11.012"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1016\/j.dnarep.2009.01.005"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.4.1233-1245.2002"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0087513"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1096\/fj.05-4869fje"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000189262.92896.0b"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.637827"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2015.06.014"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvp309"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1119(00)00122-0"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1007\/s13361-013-0619-8"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.12.029"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2004.04.031"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2013.09.018"},{"issue":"6","key":"B35","first-page":"343","article-title":"Roles for the sarco-\/endoplasmic reticulum in cardiac myocyte contraction, protein synthesis, and protein quality control","volume":"27","author":"Glembotski","year":"2012","journal-title":"Physiology (Bethesda)"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200903024"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2016.05.020"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.112.270983"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000237386.98506.f7"},{"issue":"Pt 19","key":"B40","doi-asserted-by":"crossref","first-page":"4011","DOI":"10.1242\/jcs.03163","article-title":"Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation","volume":"119","author":"Liang","year":"2006","journal-title":"J Cell Sci"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119509"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1096\/fj.05-3973fje"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3541-13.2014"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117815"},{"issue":"5","key":"B45","doi-asserted-by":"crossref","first-page":"e39","DOI":"10.1161\/RES.0000000000000110","article-title":"Measurement of reactive oxygen species, reactive nitrogen species, and redox-dependent signaling in the cardiovascular system: a scientific statement from the American Heart Association","volume":"119","author":"Griendling","year":"2016","journal-title":"Circ Res"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01233.2003"},{"issue":"3","key":"B47","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1096\/fj.10-160895","article-title":"Enhancement of proteasome function by PA28α overexpression protects against oxidative stress","volume":"25","author":"Li","year":"2011","journal-title":"FASEB J"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303787"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.219485"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2017.04.024"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-016-2255-5"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1038\/nature10353"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.08.020"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2005.09.022"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2005.7.538"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00604.2012"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2007.04.006"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.06.097"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddl017"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-016-0451-3"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.310266"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000220643.65941.8d"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1172\/JCI70877"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0706802105"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000261924.76669.36"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.041814"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq231"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1119167109"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.230607"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.048934"}],"container-title":["Journal of Clinical Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.jci.org\/articles\/view\/98287\/files\/pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,3]],"date-time":"2023-08-03T13:15:00Z","timestamp":1691068500000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.jci.org\/articles\/view\/98287"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,10,22]]},"references-count":70,"journal-issue":{"issue":"12","published-online":{"date-parts":[[2018,10,22]]},"published-print":{"date-parts":[[2018,10,22]]}},"alternative-id":["10.1172\/JCI98287"],"URL":"https:\/\/doi.org\/10.1172\/jci98287","relation":{},"ISSN":["0021-9738","1558-8238"],"issn-type":[{"value":"0021-9738","type":"print"},{"value":"1558-8238","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,10,22]]}}}