{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T13:32:59Z","timestamp":1762176779223},"reference-count":21,"publisher":"American Psychiatric Association Publishing","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP"],"published-print":{"date-parts":[[1963,7]]},"DOI":"10.1176\/ajp.120.1.80","type":"journal-article","created":{"date-parts":[[2014,12,17]],"date-time":"2014-12-17T18:27:07Z","timestamp":1418840827000},"page":"80-81","source":"Crossref","is-referenced-by-count":28,"title":["GILLES DE LA TOURETTE'S DISEASE"],"prefix":"10.1176","volume":"120","author":[{"given":"K.","family":"SINGER","sequence":"first","affiliation":[{"name":"Specialist (Psychiatry), Government of Hong Kong, Castle Peak Hospital, Hong Kong."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"230","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.2.5204.1019"},{"key":"p_3","first-page":"377","volume":"35","author":"Babiak W.","year":"1961","journal-title":"Canad. Med. Ass. J."},{"key":"p_4","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.107.446.100"},{"key":"p_5","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.24.2.90"},{"key":"p_6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(62)92173-6"},{"key":"p_7","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.119.10.994"},{"key":"p_10","unstructured":"The syndrome is characterised by the appearance in childhood and in chronological order of compulsive phenomenatics, obsessions, coprolalia, copropraxia, echolalia, echokinesis and automatic obedience. It is often associated with anxiety and other neurotic features which may be crippling. The disorder is progressive and may lead to a psychosis resembling schizophrenia. It has rarely responded to treatment and the considerable improvement obtained with chiordiazepoxide (Librium) and isocarboxazid (Marplan) in the present case is of interest. A 15-year-old Chinese boy was seen in Dec. 1960 because of multiple tics and semi-articu"},{"volume-title":"reduction of environmental stresses and supportive psychotherapy. Chlorpromazine (Thorazine) and trifluoperazine (Stelazine) reduced the tics slightly but made the patient even more apathetic","year":"1961","author":"Treatment","key":"p_16"},{"volume-title":"Within one week there was considerable overall improvement. The drugs were withdrawn","year":"1962","key":"p_18"},{"issue":"19","key":"p_20","first-page":"159","volume":"9","author":"Tourette","year":"1885","journal-title":"Arch. NeuroL (Paris)"},{"key":"p_22","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.105.4.267"},{"volume-title":"ibid., 115: 715","year":"1959","author":"Eisenberg L.","key":"p_23"},{"key":"p_24","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.105.441.1078"},{"key":"p_25","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.116.2.177"},{"key":"p_26","doi-asserted-by":"publisher","DOI":"10.1097\/00005053-196004000-00008"},{"key":"p_27","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.116.10.935"},{"volume-title":"ibid., 117: 78","year":"1960","author":"Schneck J. M.","key":"p_28"},{"key":"p_29","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1961.tb01767.x"},{"volume-title":"Psychotherapy by Reciprocal Inhibition","year":"1958","author":"Wolpe J.","key":"p_31"},{"volume-title":"Ther. Res., 4 (SuppL)","year":"1962","author":"Fogel E. J.","key":"p_36"},{"volume-title":"the treatment drug was discontinued on June 5th. Three days later, she developed edema of the face which extended to the scalp and marked puffiness of the eyelids","author":"Because","key":"p_40"}],"container-title":["American Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/psychiatryonline.org\/doi\/10.1176\/ajp.120.1.80","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T14:06:11Z","timestamp":1722348371000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/ajp.120.1.80"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1963,7]]},"references-count":21,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1963,7]]}},"alternative-id":["10.1176\/ajp.120.1.80"],"URL":"https:\/\/doi.org\/10.1176\/ajp.120.1.80","relation":{},"ISSN":["0002-953X","1535-7228"],"issn-type":[{"type":"print","value":"0002-953X"},{"type":"electronic","value":"1535-7228"}],"subject":[],"published":{"date-parts":[[1963,7]]}}}