{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:45Z","timestamp":1779148845537,"version":"3.51.4"},"reference-count":14,"publisher":"American Psychiatric Association Publishing","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP"],"published-print":{"date-parts":[[1970,11]]},"DOI":"10.1176\/ajp.127.5.671","type":"journal-article","created":{"date-parts":[[2014,12,17]],"date-time":"2014-12-17T18:38:23Z","timestamp":1418841503000},"page":"671-677","source":"Crossref","is-referenced-by-count":23,"title":["The Lesch-Nyhan Syndrome"],"prefix":"10.1176","volume":"127","author":[{"given":"LARRY H.","family":"DIZMANG","sequence":"first","affiliation":[{"name":"Coordinator of intramural research in the center for studies of suicide prevention, National Institute of Mental Health, 5454 Wisconsin Ave., Chevy Chase, Md. 20015"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"CLAUDIA F.","family":"CHEATHAM","sequence":"additional","affiliation":[{"name":"Coordinator of intramural research in the center for studies of suicide prevention, National Institute of Mental Health, 5454 Wisconsin Ave., Chevy Chase, Md. 20015"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"230","reference":[{"key":"p_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(64)90104-4"},{"key":"p_2","first-page":"1047","volume":"27","author":"Kelley WN","year":"1968","journal-title":"Fed Proc"},{"key":"p_3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196507152730303"},{"key":"p_4","first-page":"1067","volume":"27","author":"Balis ME","year":"1968","journal-title":"Fed Proc"},{"key":"p_5","first-page":"1053","volume-title":"Ibid","author":"Henderson F"},{"key":"p_6","unstructured":"Henderson iF: Possible functions of hypoxanthineguanine phosphonibosyltransferase and their relation to the biochemical pathology of the Lesch-Nyhan syndrome. Ibid. pp1075-1077"},{"key":"p_7","unstructured":"Henderson iF: Inheritance of hypoxanthineguanine phosphoribosyltransferase deficiency and detection of heterozygotes. Ibid. pp1085-1086"},{"key":"p_8","unstructured":"Hoefnagel D: Lesch-Nyhan syndrome: pathology and pathologic physiology. Ibid. pp1042-1046"},{"key":"p_9","unstructured":"Howell RR: Hyperuricemia in childhood. Ibid. pp1078-1082"},{"key":"p_10","unstructured":"Nyhan WL: Clinical features of the Lesch-Nyhan syndrome. Ibid. pp1027-1041"},{"key":"p_11","unstructured":"Rosenbloom FM: Possible mechanism for increased purine biosynthesis de novo in Lesch-Nyhan syndrome. Ibid. pp1063-1066"},{"key":"p_12","unstructured":"Seegmiller JE Lesch-Nyhan syndrome: management and treatment. Ibid. pp1097-1104"},{"key":"p_13","unstructured":"Sweetman L: Urinary and cerebrospinal fluid oxypurine levels and allopuninol metabolism in the Lesch-Nyhan syndrome. Ibid. pp1055-1059"},{"key":"p_14","first-page":"171","volume":"19","author":"Green AH","year":"1968","journal-title":"ArchGenPsychiat"}],"container-title":["American Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/psychiatryonline.org\/doi\/10.1176\/ajp.127.5.671","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T20:50:16Z","timestamp":1722372616000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/ajp.127.5.671"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1970,11]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1970,11]]}},"alternative-id":["10.1176\/ajp.127.5.671"],"URL":"https:\/\/doi.org\/10.1176\/ajp.127.5.671","relation":{},"ISSN":["0002-953X","1535-7228"],"issn-type":[{"value":"0002-953X","type":"print"},{"value":"1535-7228","type":"electronic"}],"subject":[],"published":{"date-parts":[[1970,11]]}}}