{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T08:18:17Z","timestamp":1789460297706,"version":"build-2803163510"},"reference-count":5,"publisher":"American Psychiatric Association Publishing","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP"],"published-print":{"date-parts":[[2003,8,1]]},"DOI":"10.1176\/appi.ajp.160.8.1514","type":"journal-article","created":{"date-parts":[[2003,8,4]],"date-time":"2003-08-04T17:35:14Z","timestamp":1060018514000},"page":"1514-1516","source":"Crossref","is-referenced-by-count":47,"title":["Clozapine as a First Treatment for Schizophrenia"],"prefix":"10.1176","volume":"160","author":[{"given":"Margaret G.","family":"Woerner","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Delbert G.","family":"Robinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Ma. J.","family":"Alvir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian B.","family":"Sheitman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey A.","family":"Lieberman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Kane","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","reference":[{"key":"R1608CHDCHDFF","doi-asserted-by":"crossref","unstructured":"Wahlbeck K, Cheine M, Essali A, Adams C: Evidence of clozapine\u2019s effectiveness in schizophrenia: a systematic review and meta-analysis of randomized trials. Am J Psychiatry 1999; 156:990\u2013999","DOI":"10.1176\/ajp.156.7.990"},{"key":"R1608CHDIGHCB","doi-asserted-by":"crossref","unstructured":"Lieberman JA, Alvir JM, Woerner MG, Degreef G, Bilder R, Ashtari M, Bogerts B, Mayerhoff DI, Loebel A, Levy D, Hinrichsen G, Szymanski S, Chakos M, Borenstein M, Kane JM: Prospective study of psychobiology in first-episode schizophrenia at Hillside Hospital. Schizophr Bull 1992; 18:351\u2013371","DOI":"10.1093\/schbul\/18.3.351"},{"key":"R1608CHDBIIJB","doi-asserted-by":"crossref","unstructured":"Endicott J, Spitzer RL: A diagnostic interview: the Schedule for Affective Disorders and Schizophrenia. Arch Gen Psychiatry 1978; 35:837\u2013844","DOI":"10.1001\/archpsyc.1978.01770310043002"},{"key":"R1608CHDHFEDJ","doi-asserted-by":"crossref","unstructured":"Robinson DG, Woerner MG, Alvir JMJ, Geisler S, Koreen A, Sheitman B, Chakos M, Mayerhoff D, Bilder R, Goldman R, Lieberman JA: Predictors of treatment response from a first episode of schizophrenia or schizoaffective disorder. Am J Psychiatry 1999; 156:544\u2013549","DOI":"10.1176\/ajp.156.4.544"},{"key":"R1608CHDEDEGJ","doi-asserted-by":"crossref","unstructured":"Lieberman JA, Phillips M, Gu H, KStroup S, Zhang P, Kong L, Ji Z, Koch G, Hamer RM: Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52 week randomized trial of clozapine vs chlorpromazine. Neuropsychopharmacology 2003; 28:995\u20131993","DOI":"10.1038\/sj.npp.1300157"}],"container-title":["American Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/psychiatryonline.org\/doi\/10.1176\/appi.ajp.160.8.1514","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T19:50:45Z","timestamp":1721850645000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.ajp.160.8.1514"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8,1]]},"references-count":5,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2003,8,1]]}},"alternative-id":["10.1176\/appi.ajp.160.8.1514"],"URL":"https:\/\/doi.org\/10.1176\/appi.ajp.160.8.1514","relation":{},"ISSN":["0002-953X","1535-7228"],"issn-type":[{"value":"0002-953X","type":"print"},{"value":"1535-7228","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8,1]]}}}