{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T03:18:57Z","timestamp":1792725537989,"version":"4.5.0"},"reference-count":43,"publisher":"American Psychiatric Association Publishing","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP"],"published-print":{"date-parts":[[2016,3,1]]},"DOI":"10.1176\/appi.ajp.2015.15020164","type":"journal-article","created":{"date-parts":[[2015,11,6]],"date-time":"2015-11-06T03:03:15Z","timestamp":1446778995000},"page":"271-281","source":"Crossref","is-referenced-by-count":173,"title":["An 8-Week Randomized, Double-Blind, Placebo-Controlled Evaluation of the Safety and Efficacy of Cariprazine in Patients With Bipolar I Depression"],"prefix":"10.1176","volume":"173","author":[{"given":"Suresh","family":"Durgam","sequence":"first","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Willie","family":"Earley","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Lipschitz","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Guo","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Istv\u00e1n","family":"Laszlovszky","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gy\u00f6rgy","family":"N\u00e9meth","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Vieta","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joseph R.","family":"Calabrese","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lakshmi N.","family":"Yatham","sequence":"additional","affiliation":[{"name":"From Forest Research Institute, Jersey City, N.J.; Gedeon Richter, Budapest; Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain; University Hospitals Case Medical Center, Case Western Reserve School of Medicine, Cleveland; and University of British Columbia, Vancouver."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3109\/10673221003747955"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2010.00812.x"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.109.160432"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2011.07.002"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1001\/archgenpsychiatry.2009.43"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2011.05.005"},{"key":"B9","first-page":"S520","volume":"38","author":"Slifstein M","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-clinpsy-050212-185606"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.07.022"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2014.07.055"},{"key":"B13","first-page":"S84","volume":"38","author":"Duman RS","year":"2012","journal-title":"Neuropsychopharmacol."},{"key":"B14","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1097\/FBP.0000000000000070","volume":"25","author":"Papp M","year":"2014","journal-title":"Behav Pharmacol"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(96)00242-4"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14m09081"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12238"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.11.018"},{"key":"B19","unstructured":"Ahuja S, Bose A, Lu K, et al: A multicenter, randomized, double-blind trial to evaluate the effect of cariprazine in bipolar depression. Poster presented at the Autumn Conference of the International Society for CNS Clinical Trials and Methodology, Amelia Island, Fla, Oct 3\u20134, 2011"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.23.1.56"},{"key":"B21","doi-asserted-by":"crossref","unstructured":"Guy W: ECDEU Assessment Manual for Psychopharmacology. Publication ADM 76-338. Washington, DC, US Department of Health, Education, and Welfare, 1976, pp 218\u2013222","DOI":"10.1037\/e591322011-001"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.134.4.382"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.133.5.429"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2011.10111704"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.154.5.672"},{"key":"B26","doi-asserted-by":"crossref","unstructured":"Guy W: ECDEU Assessment Manual for Psychopharmacology: Publication ADM 76-338. Washington, DC, US Department of Health, Education, and Welfare, 1976, pp 534\u2013537","DOI":"10.1037\/e591322011-001"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.1970.tb02066.x"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1093\/biomet\/90.1.53"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-002-1147-6"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1002\/sim.2005"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-0327(99)00162-7"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.7.1351"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1097\/01.jcp.0000248603.76231.b7"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04995gre"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04942gre"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.10.007"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.13070984"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.112.108357"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.60.11.1079"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1177\/0269881111408461"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145709990344"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e31825ccde5"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1097\/jcp.0b013e3181618eb4"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.13020185"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2008.00625.x"}],"container-title":["American Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ajp.psychiatryonline.org\/doi\/10.1176\/appi.ajp.2015.15020164","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T12:57:23Z","timestamp":1722344243000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.ajp.2015.15020164"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,3,1]]},"references-count":43,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,3,1]]}},"alternative-id":["10.1176\/appi.ajp.2015.15020164"],"URL":"https:\/\/doi.org\/10.1176\/appi.ajp.2015.15020164","relation":{},"ISSN":["0002-953X","1535-7228"],"issn-type":[{"value":"0002-953X","type":"print"},{"value":"1535-7228","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,3,1]]}}}