{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T18:28:17Z","timestamp":1793125697628,"version":"4.5.0"},"reference-count":94,"publisher":"American Psychiatric Association Publishing","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP"],"published-print":{"date-parts":[[2022,2]]},"DOI":"10.1176\/appi.ajp.2021.21030320","type":"journal-article","created":{"date-parts":[[2021,12,8]],"date-time":"2021-12-08T08:00:47Z","timestamp":1638950447000},"page":"98-109","source":"Crossref","is-referenced-by-count":86,"title":["Risks and Benefits of Cannabis and Cannabinoids in Psychiatry"],"prefix":"10.1176","volume":"179","author":[{"given":"Kevin P.","family":"Hill","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark S.","family":"Gold","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7867-1160","authenticated-orcid":false,"given":"Charles B.","family":"Nemeroff","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William","family":"McDonald","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5952-6953","authenticated-orcid":false,"given":"Adrienne","family":"Grzenda","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8510-341X","authenticated-orcid":false,"given":"Alik S.","family":"Widge","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolyn","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nina V.","family":"Kraguljac","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Krystal","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Linda L.","family":"Carpenter","sequence":"additional","affiliation":[{"name":"Department of Psychiatry, Harvard Medical School, Boston, andBeth Israel Deaconess Medical Center, Boston (Hill);Department of Psychiatry, School of Medicine, Washington University in St. Louis (Gold);Department of Psychiatry, Dell Medical School, University of Texas at Austin (Nemeroff);Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta (McDonald);Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles (Grzenda..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","reference":[{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.18900"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1080\/10826084.2019.1664591"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(16)30208-5"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.11868"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2020.116717"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27740"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1300496"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1089\/can.2016.0034"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1211204110"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-019-00983-5"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1002\/j.2051-5545.2008.tb00158.x"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000883"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1402309"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.7982"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2015.1858"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1001\/jamapediatrics.2018.3096"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.3998\/2027.42\/162579"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.7326\/M20-1212"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0233147"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.2648"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-020-00880-7"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.7326\/M18-2809"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2012.08.023"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1097\/ADM.0b013e31820cdd57"},{"key":"B26","first-page":"199253","volume":"11","author":"Casey JL","year":"2020","journal-title":"Addict Behav Rep"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2012.01.039"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2021.1258"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2008.10.021"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/j.addbeh.2014.01.019"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1111\/j.1369-1600.2007.00074.x"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/aws136"},{"key":"B33","first-page":"642","volume":"17","author":"Meier MH","year":"2012","journal-title":"Proc Natl Acad Sci USA"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.0335"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.02.065"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1920866117"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugpo.2014.07.011"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2016.01.014"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0153327"},{"key":"B40","first-page":"169","volume":"17","author":"Zehra A","year":"2019","journal-title":"Focus Am Psychiatr Publ"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1002\/hup.1048"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.10.006"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291713001438"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1046\/j.1360-0443.2003.00437.x"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.13025"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(19)30048-3"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2021.1471"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbt181"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(20)30339-4"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(19)30401-8"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1016\/j.smrv.2007.12.004"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1007\/s13181-016-0595-z"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.12962"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1007\/s11883-019-0783-9"},{"key":"B57","first-page":"e3195","volume":"10","author":"Desai R","year":"2018","journal-title":"Cureus"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1097\/JU.0000000000000248"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2015.01.004"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.8734"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1300\/J069v22n03_05"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1611618"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30136-3"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.6199"},{"key":"B68","volume-title":"The Health Effects of Cannabis and Cannabinoids: The Current State of Evidence and Recommendations for Research.","author":"National Academies of Sciences, Engineering, and Medicine","year":"2017"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.6358"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.7326\/M17-0155"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1097\/j.pain.0000000000001293"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2018.3485"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000250"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2018.2503"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1186\/s12954-019-0278-6"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1016\/j.psyneuen.2014.11.002"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.14m09475"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0246990"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1016\/j.drugalcdep.2010.12.010"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1111\/ajad.12622"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-009-1506-7"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1038\/nn.3540"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2019.18101191"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1111\/add.13693"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2014.4005"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1903434116"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2017.02.041"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2019.4157"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.11909"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1159\/000489287"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1186\/s12888-019-2022-x"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1111\/bcp.14399"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1038\/tp.2012.15"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2017.17030325"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-018-4885-9"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1007\/s11606-020-06504-8"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.2071"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2019.19010035"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1111\/add.14984"},{"key":"B101","first-page":"410","volume":"117","author":"Gold MS","year":"2020","journal-title":"Missouri Medicine"}],"container-title":["American Journal of Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/ajp.psychiatryonline.org\/doi\/10.1176\/appi.ajp.2021.21030320","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,30]],"date-time":"2024-07-30T13:41:07Z","timestamp":1722346867000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.ajp.2021.21030320"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2]]},"references-count":94,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2]]}},"alternative-id":["10.1176\/appi.ajp.2021.21030320"],"URL":"https:\/\/doi.org\/10.1176\/appi.ajp.2021.21030320","relation":{},"ISSN":["0002-953X","1535-7228"],"issn-type":[{"value":"0002-953X","type":"print"},{"value":"1535-7228","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2]]}}}