{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T04:54:34Z","timestamp":1784350474158,"version":"3.55.0"},"reference-count":33,"publisher":"American Psychiatric Association Publishing","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["AJP"],"published-print":{"date-parts":[[2025,4,1]]},"DOI":"10.1176\/appi.ajp.20240321","type":"journal-article","created":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T08:00:42Z","timestamp":1739952042000},"page":"341-348","source":"Crossref","is-referenced-by-count":13,"title":["Continuous Dopamine D<sub>2<\/sub> Receptor Blockade and Long-Term Outcome in First-Episode Schizophrenia"],"prefix":"10.1176","volume":"182","author":[{"given":"Jari","family":"Tiihonen","sequence":"first","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antti","family":"Tanskanen","sequence":"additional","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4877-7233","authenticated-orcid":false,"given":"Marco","family":"Solmi","sequence":"additional","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose M.","family":"Rubio","sequence":"additional","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christoph U.","family":"Correll","sequence":"additional","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John M.","family":"Kane","sequence":"additional","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3281-934X","authenticated-orcid":false,"given":"Heidi","family":"Taipale","sequence":"additional","affiliation":[{"name":"Department of Forensic Psychiatry, University of Eastern Finland, and Niuvanniemi Hospital, Kuopio, Finland (Tiihonen, Tanskanen, Taipale); Department of Clinical Neuroscience, Karolinska Institutet, Stockholm (Tiihonen, Tanskanen, Taipale); Center for Psychiatry Research, Stockholm City Council, Stockholm (Tiihonen, Tanskanen, Taipale); SCIENCES Lab and Department of Psychiatry, University of Ottawa, Ottawa (Solmi); On Track: The Champlain First Episode Psychosis Program, and Regional Centre for the Treatment of Eating Disorders, Department of Mental Health, Ottawa Hospital, Ottawa (Solmi); Clinical Epidemiology Program, Ottawa Hospital Research Institute, Ottawa (Solmi); Department of Child and Adolescent Psychiatry, Charit\u00e9\u2013Universit\u00e4tsmedizin Berlin, Berlin (Solmi, Correll); Department of Psychiatry, Zucker Hillside Hospital, Northwell Health, Glen Oaks, NY (Rubio, Correll, Kane); Department of Psychiatry and Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra\/Northwell, Hempste..."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)02190-6"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbab094"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20972"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)01997-8"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1002\/wps.21089"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409766102"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1007\/s002130000532"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.5416-06.2007"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.116.182683"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1159\/000477313"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X14666160606093602"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1001\/jamapsychiatry.2013.19"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291714000610"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1002\/wps.20516"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852920001546"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(23)00258-4"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbs150"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291719001296"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2019.11.025"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(20)30264-9"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbad145"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1186\/s12911-015-0140-z"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(22)00015-3"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1017\/S1092852918001098"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.67"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S117321"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1002\/wps.21056"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1176\/ajp.137.1.16"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60239-6"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-020-00879-0"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2021.06.010"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2018.17091001"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1016\/j.schres.2011.11.021"}],"container-title":["American Journal of Psychiatry"],"original-title":[],"language":"en","deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T18:06:25Z","timestamp":1745431585000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.ajp.20240321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,1]]},"references-count":33,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2025,4,1]]}},"alternative-id":["10.1176\/appi.ajp.20240321"],"URL":"https:\/\/doi.org\/10.1176\/appi.ajp.20240321","relation":{},"ISSN":["0002-953X","1535-7228"],"issn-type":[{"value":"0002-953X","type":"print"},{"value":"1535-7228","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,4,1]]}}}