{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T18:09:58Z","timestamp":1785607798290,"version":"3.56.0"},"reference-count":109,"publisher":"American Psychiatric Association Publishing","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2019,7]]},"DOI":"10.1176\/appi.focus.20190008","type":"journal-article","created":{"date-parts":[[2019,7,18]],"date-time":"2019-07-18T13:27:06Z","timestamp":1563456426000},"page":"218-231","source":"Crossref","is-referenced-by-count":12,"title":["Complex Combination Pharmacotherapy for Bipolar Disorder: Knowing When Less Is More or More Is Better"],"prefix":"10.1176","volume":"17","author":[{"given":"Joseph F.","family":"Goldberg","sequence":"first","affiliation":[{"name":"Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York City."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.158.3.420"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.06.005"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2014.01.038"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04301"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1080\/13651500510029200"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0028725"},{"key":"B7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1176\/appi.ajp.159.1.1","volume":"159","author":"American Psychiatric Association","year":"2002","journal-title":"Am J Psychiatry"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12609"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v66n0710"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1097\/YIC.0b013e3283639015"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.163.2.210"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.18m12200"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2017.12.071"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.13020185"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ps.201200529"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145713000953"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0000000000000175"},{"key":"B19","first-page":"72","volume":"40","author":"Dennehy EB","year":"2007","journal-title":"Psychopharmacol Bull"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1185\/030079906X167444"},{"key":"B21","first-page":"136","volume":"2","author":"Manji HK","year":"2003","journal-title":"World Psychiatry"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-013-0039-0"},{"key":"B23","first-page":"23","volume":"57","author":"Lenox RH","year":"1996","journal-title":"J Clin Psychiatry"},{"key":"B24","first-page":"123","volume":"48","author":"Morishita S","year":"1994","journal-title":"Jpn J Psychiatry Neurol"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v65n0610"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2009.01.028"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-008-9817-3"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145710001082"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2011.10.007"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1111\/pcn.12242"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0172270"},{"key":"B32","first-page":"82","volume":"61","author":"Manji HK","year":"2000","journal-title":"J Clin Psychiatry"},{"key":"B33","first-page":"3","volume":"64","author":"Gray NA","year":"2003","journal-title":"J Clin Psychiatry"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145712000429"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2004.02.064"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301527"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.16.8455"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(03)00187-4"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.neures.2011.08.010"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1093\/ijnp\/pyu099"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/0364-7722(81)90040-0"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0082(98)00075-6"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1007\/BF00964170"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopsych.2007.04.021"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2011.03.006"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1167.2007.01526.x"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcn.2013.07.006"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2007.08.018"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1007\/BF00228395"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3908(99)00058-1"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1111\/j.1528-1157.1997.tb01135.x"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1124\/mol.106.026419"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/S0893-133X(99)00042-1"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.07.025"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-008-9595-y"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2007.00530.x"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.10r06710"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.f3646"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.13m08413"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(17)30046-9"},{"key":"B61","first-page":"25","volume":"60","author":"Swann AC","year":"1999","journal-title":"J Clin Psychiatry"},{"key":"B62","volume":"17","author":"Goldberg JF","year":"2019","journal-title":"Focus"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.115.180281"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2008.07101560"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1097\/JCP.0b013e31823f872f"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12324"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.59.1.62"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04895yel"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.159.7.1146"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2004.00115.x"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1186\/s40345-014-0014-9"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.08.015"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.107.041301"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2010.09.011"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n1105"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.11m07388"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04152"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1016\/S2215-0366(15)00450-2"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2013.13070985"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05934"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2011.00898.x"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)61828-6"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2012.11.042"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.184.4.337"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2009.00761.x"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05482yel"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2017.06.013"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1017\/S1461145708008596"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1097\/WNF.0000000000000147"},{"key":"B90","doi-asserted-by":"publisher","DOI":"10.2147\/NDT.S100846"},{"key":"B91","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-36392"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.12060751"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05019yel"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1001\/jama.290.11.1467"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2007.05081484"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.v67n0401"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa064135"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2018.33.e290"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04942gre"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04912gre"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.09m05214yel"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12013"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04191"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04909gre"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.11.2152"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2015.158"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1038\/sj.npp.1301131"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1991.01810330075011"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2014.05.026"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.2012.12010112"}],"container-title":["Focus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.focus.20190008","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,31]],"date-time":"2024-07-31T00:36:18Z","timestamp":1722386178000},"score":1,"resource":{"primary":{"URL":"https:\/\/psychiatryonline.org\/doi\/10.1176\/appi.focus.20190008"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7]]},"references-count":109,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2019,7]]}},"alternative-id":["10.1176\/appi.focus.20190008"],"URL":"https:\/\/doi.org\/10.1176\/appi.focus.20190008","relation":{},"ISSN":["1541-4094","1541-4108"],"issn-type":[{"value":"1541-4094","type":"print"},{"value":"1541-4108","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7]]}}}