{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T22:01:41Z","timestamp":1793138501351,"version":"4.5.0"},"reference-count":59,"publisher":"American Psychiatric Association Publishing","issue":"3","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psych Res and Clin Practice"],"published-print":{"date-parts":[[2024,9]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Psychiatric disorders are associated with impairments in quality of life (QOL) and functioning. What remained to be investigated was the comparison of these constructs across psychiatric disorders in treatment\u2010seeking adults. It was hypothesized that mood disorder patients would endorse worse QOL and functioning at entry into psychiatric outpatient treatment compared to patients with other disorders, and that regardless of diagnosis, severe impairments in QOL and functioning would be endorsed by the majority of the sample (&gt;70%).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Data were collected for 2114 adults. Diagnostic and Statistical Manual of Mental Disorders diagnoses were obtained using the Mini International Neuropsychiatric Interview. Patients completed measures of QOL (Q\u2010LES\u2010Q), functioning (Work and Social Adjustment Scale [WSAS], Sheehan Disability Scale, Endicott Work Productivity Scale), and depression (Quick Inventory of Depressive Symptomatology\u2010Self Report).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Overall, 70.6% of patients with psychiatric disorders reported severe impairment in QOL and 59.6% of patients reported severe impairment in functioning (per the WSAS). Patients with mood disorders were more likely to report severe impairments in QOL and functioning, compared to patients with other psychiatric disorders. Analysis of variance revealed patients with mood disorders reported significantly lower QOL, worse functioning, and greater depressive symptom severity compared to patients without mood disorders (all\n                      <jats:italic>p<\/jats:italic>\n                      values\u00a0&lt;0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Patients with psychiatric conditions overwhelmingly reported severely impaired QOL and functioning at entry to outpatient treatment. Patients with mood disorders were disproportionately more likely to endorse severely impaired QOL and functioning, particularly those with Major Depressive Disorder, recurrent, and Bipolar Disorder I, depressive episode. Findings suggest that future treatment efforts should focus on interventions that restore QOL and functioning in psychiatric patients, particularly among those with mood disorders.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1176\/appi.prcp.20230064","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T12:13:16Z","timestamp":1712578396000},"page":"68-77","source":"Crossref","is-referenced-by-count":11,"title":["Quality of Life and Functioning Impairments Across Psychiatric Disorders in Adults Presenting for Outpatient Psychiatric Evaluation and Treatment"],"prefix":"10.1176","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1970-4756","authenticated-orcid":false,"given":"Waguih William","family":"IsHak","sequence":"first","affiliation":[{"name":"Department of Psychiatry and Behavioral Neurosciences Cedars\u2010Sinai Medical Center  Los Angeles California USA"},{"name":"Department of Psychiatry and Biobehavioral Sciences David Geffen School of Medicine University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James","family":"Mirocha","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neurosciences Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan","family":"Dang","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neurosciences Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Vanle","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neurosciences Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin","family":"Metrikin","sequence":"additional","affiliation":[{"name":"Kaiser Permanente Bernard J. Tyson School of Medicine  Pasadena California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaleab","family":"Tessema","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Biobehavioral Sciences David Geffen School of Medicine University of California Los Angeles  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5384-9970","authenticated-orcid":false,"given":"Alexander J.","family":"Steiner","sequence":"additional","affiliation":[{"name":"Executive Mental Health, Inc.  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Itai","family":"Danovitch","sequence":"additional","affiliation":[{"name":"Department of Psychiatry and Behavioral Neurosciences Cedars\u2010Sinai Medical Center  Los Angeles California USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"230","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/s1121189x00001421"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1097\/nmd.0b013e3181c81708"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.mp.4001777"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.61.11.1097"},{"key":"e_1_2_6_6_1","volume-title":"Measuring healthy days: population assessment of health\u2010related quality of life","author":"Centers for Disease Control and Prevention","year":"2000"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890423349"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.3310\/hta16280"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/mp.2008.13"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.psy.48.4.331"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100447.1996.tb10671.x"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1177\/2040622316639769"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2013.05.048"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/acps.12301"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2021.04.052"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11136\u2010020\u201002470\u20100"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1134032"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12955\u2010020\u201001310\u20106"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1159\/000437299"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.47102\/annals\u2010acadmedsg.v47n7p243"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1093\/schbul\/sbad075"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1017\/s2045796018000549"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1186\/1477\u20107525\u20103\u201072"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182212022"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.bp.114.157115"},{"key":"e_1_2_6_26_1","first-page":"34","article-title":"The Mini\u2010International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM\u2010IV and ICD\u201010","volume":"59","author":"Sheehan DV","year":"1998","journal-title":"J Clin Psychiatr"},{"key":"e_1_2_6_27_1","first-page":"321","article-title":"Quality of life enjoyment and satisfaction questionnaire: a new measure","volume":"29","author":"Endicott J","year":"1993","journal-title":"Psychopharmacol Bull"},{"key":"e_1_2_6_28_1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.ajp.162.6.1171"},{"key":"e_1_2_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2006.09.008"},{"key":"e_1_2_6_30_1","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.180.5.461"},{"key":"e_1_2_6_31_1","doi-asserted-by":"publisher","DOI":"10.1053\/comp.2003.50024"},{"key":"e_1_2_6_32_1","first-page":"13","article-title":"Endicott Work Productivity Scale (EWPS): a new measure to assess treatment effects","volume":"33","author":"Endicott J","year":"1997","journal-title":"Psychopharmacol Bull"},{"key":"e_1_2_6_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0006\u20103223(02)01866\u20108"},{"key":"e_1_2_6_34_1","first-page":"12","article-title":"The link between depression and physical symptoms","volume":"6","author":"Trivedi MH","year":"2004","journal-title":"Prim Care Companion J Clin Psychiatry"},{"key":"e_1_2_6_35_1","doi-asserted-by":"publisher","DOI":"10.1037\/\/0022\u2010006x.56.6.893"},{"key":"e_1_2_6_36_1","volume-title":"Beck Anxiety Inventory manual","author":"Beck AT","year":"1990"},{"key":"e_1_2_6_37_1","unstructured":"World Health Organization.Preamble to the constitution of the World Health Organization.1948[cited 2012 Oct 1]. 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